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Volumn 70, Issue 21, 2010, Pages 8748-8759

Tumor cell kill by c-MYC depletion: Role of MYC-regulated genes that control DNA double-strand break repair

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DOUBLE STRANDED DNA; GREEN FLUORESCENT PROTEIN; KU ANTIGEN; MITOMYCIN C; MYC PROTEIN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN KINASE C; RAD50 PROTEIN; RAD51 PROTEIN; RAD51B PROTEIN; RAD51C PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; XRCC2 PROTEIN; XRCC4 PROTEIN;

EID: 78449286445     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0944     Document Type: Article
Times cited : (82)

References (47)
  • 1
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008;8:976-90.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 3
    • 53349103292 scopus 로고    scopus 로고
    • Modelling Myc inhibition as a cancer therapy
    • Soucek L, Whitfield J, Martins CP, et al. Modelling Myc inhibition as a cancer therapy. Nature 2008;455:679-83.
    • (2008) Nature , vol.455 , pp. 679-683
    • Soucek, L.1    Whitfield, J.2    Martins, C.P.3
  • 4
    • 0023954113 scopus 로고
    • An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation
    • Holt JT, Redner RL, Nienhuis AW. An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation. Mol Cell Biol 1988;8:963-73.
    • (1988) Mol Cell Biol , vol.8 , pp. 963-973
    • Holt, J.T.1    Redner, R.L.2    Nienhuis, A.W.3
  • 5
    • 0028935119 scopus 로고
    • Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells
    • Kimura S, Maekawa T, Hirakawa K, Murakami A, Abe T. Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res 1995;55:1379-84.
    • (1995) Cancer Res , vol.55 , pp. 1379-1384
    • Kimura, S.1    Maekawa, T.2    Hirakawa, K.3    Murakami, A.4    Abe, T.5
  • 6
    • 23844448634 scopus 로고    scopus 로고
    • Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo
    • Wang YH, Liu S, Zhang G, et al. Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo. Breast Cancer Res 2005;7:R220-8.
    • (2005) Breast Cancer Res , vol.7
    • Wang, Y.H.1    Liu, S.2    Zhang, G.3
  • 7
    • 0037479844 scopus 로고    scopus 로고
    • Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a phase I safety study in humans
    • Iversen PL, Arora V, Acker AJ, Mason DH, Devi GR. Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a phase I safety study in humans. Clin Cancer Res 2003;9:2510-9.
    • (2003) Clin Cancer Res , vol.9 , pp. 2510-2519
    • Iversen, P.L.1    Arora, V.2    Acker, A.J.3    Mason, D.H.4    Devi, G.R.5
  • 8
    • 0037805645 scopus 로고    scopus 로고
    • c-Myc directly regulates the transcription of the NBS1 gene involved in DNA doublestrand break repair
    • Chiang YC, Teng SC, Su YN, Hsieh FJ, Wu KJ. c-Myc directly regulates the transcription of the NBS1 gene involved in DNA doublestrand break repair. J Biol Chem 2003;278:19286-91.
    • (2003) J Biol Chem , vol.278 , pp. 19286-19291
    • Chiang, Y.C.1    Teng, S.C.2    Su, Y.N.3    Hsieh, F.J.4    Wu, K.J.5
  • 9
    • 0037718341 scopus 로고    scopus 로고
    • Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
    • Mao DY, Watson JD, Yan PS, et al. Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression. Curr Biol 2003;13:882-6.
    • (2003) Curr Biol , vol.13 , pp. 882-886
    • Mao, D.Y.1    Watson, J.D.2    Yan, P.S.3
  • 10
    • 0038185378 scopus 로고    scopus 로고
    • Genomic targets of the human c-Myc protein
    • Fernandez PC, Frank SR, Wang L, et al. Genomic targets of the human c-Myc protein. Genes Dev 2003;17:1115-29.
    • (2003) Genes Dev , vol.17 , pp. 1115-1129
    • Fernandez, P.C.1    Frank, S.R.2    Wang, L.3
  • 12
    • 20244377520 scopus 로고    scopus 로고
    • Myc down-regulation sensitizes melanoma cells to radiotherapy by inhibiting MLH1 and MSH2 mismatch repair proteins
    • Bucci B, D'Agnano I, Amendola D, et al. Myc down-regulation sensitizes melanoma cells to radiotherapy by inhibiting MLH1 and MSH2 mismatch repair proteins. Clin Cancer Res 2005;11:2756-67.
    • (2005) Clin Cancer Res , vol.11 , pp. 2756-2767
    • Bucci, B.1    D'Agnano, I.2    Amendola, D.3
  • 13
    • 34248385293 scopus 로고    scopus 로고
    • Co-repression of mismatch repair gene expression by hypoxia in cancer cells: Role of the Myc/Max network
    • Bindra RS, Glazer PM. Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network. Cancer Lett 2007;252:93-103.
    • (2007) Cancer Lett , vol.252 , pp. 93-103
    • Bindra, R.S.1    Glazer, P.M.2
  • 14
    • 0037197962 scopus 로고    scopus 로고
    • Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes
    • Menssen A, Hermeking H. Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes. Proc Natl Acad Sci U S A 2002;99:6274-9.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6274-6279
    • Menssen, A.1    Hermeking, H.2
  • 15
    • 34250343422 scopus 로고    scopus 로고
    • Homologous recombination and prostate cancer: A model for novel DNA repair targets and therapies
    • Bristow RG, Ozcelik H, Jalali F, Chan N, Vesprini D. Homologous recombination and prostate cancer: a model for novel DNA repair targets and therapies. Radiother Oncol 2007;83:220-30.
    • (2007) Radiother Oncol , vol.83 , pp. 220-230
    • Bristow, R.G.1    Ozcelik, H.2    Jalali, F.3    Chan, N.4    Vesprini, D.5
  • 16
    • 28244443670 scopus 로고    scopus 로고
    • Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo
    • Al Rashid ST, Dellaire G, Cuddihy A, et al. Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo. Cancer Res 2005;65:10810-21.
    • (2005) Cancer Res , vol.65 , pp. 10810-10821
    • Al Rashid, S.T.1    Dellaire, G.2    Cuddihy, A.3
  • 17
    • 39049163047 scopus 로고    scopus 로고
    • Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
    • Chan N, Koritzinsky M, Zhao H, et al. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res 2008;68:605-14.
    • (2008) Cancer Res , vol.68 , pp. 605-614
    • Chan, N.1    Koritzinsky, M.2    Zhao, H.3
  • 18
    • 28444478320 scopus 로고    scopus 로고
    • Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells
    • Meng AX, Jalali F, Cuddihy A, et al. Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. Radiother Oncol 2005;76:168-76.
    • (2005) Radiother Oncol , vol.76 , pp. 168-176
    • Meng, A.X.1    Jalali, F.2    Cuddihy, A.3
  • 19
    • 10944230682 scopus 로고    scopus 로고
    • The interaction of p53 with replication protein A mediates suppression of homologous recombination
    • Romanova LY, Willers H, Blagosklonny MV, Powell SN. The interaction of p53 with replication protein A mediates suppression of homologous recombination. Oncogene 2004;23:9025-33.
    • (2004) Oncogene , vol.23 , pp. 9025-9033
    • Romanova, L.Y.1    Willers, H.2    Blagosklonny, M.V.3    Powell, S.N.4
  • 20
    • 0025317564 scopus 로고
    • Negative autoregulation of c-myc transcription
    • Penn LJ, Brooks MW, Laufer EM, Land H. Negative autoregulation of c-myc transcription. EMBO J 1990;9:1113-21.
    • (1990) EMBO J , vol.9 , pp. 1113-1121
    • Penn, L.J.1    Brooks, M.W.2    Laufer, E.M.3    Land, H.4
  • 21
    • 0037248566 scopus 로고    scopus 로고
    • Cell death in irradiated prostate epithelial cells: Role of apoptotic and clonogenic cell kill
    • Bromfield GP, Meng A, Warde P, Bristow RG. Cell death in irradiated prostate epithelial cells: role of apoptotic and clonogenic cell kill. Prostate Cancer Prostatic Dis 2003;6:73-85.
    • (2003) Prostate Cancer Prostatic Dis , vol.6 , pp. 73-85
    • Bromfield, G.P.1    Meng, A.2    Warde, P.3    Bristow, R.G.4
  • 22
    • 0347986759 scopus 로고    scopus 로고
    • Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer
    • Ma N, Szmitko P, Brade A, et al. Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer. Cancer Gene Ther 2004;11:52-60.
    • (2004) Cancer Gene Ther , vol.11 , pp. 52-60
    • Ma, N.1    Szmitko, P.2    Brade, A.3
  • 23
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003;30:256-68.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 24
    • 37349131080 scopus 로고    scopus 로고
    • Cytoplasmic p53 is not required for PUMA-induced apoptosis
    • Callus BA, Ekert PG, Heraud JE, et al. Cytoplasmic p53 is not required for PUMA-induced apoptosis. Cell Death Differ 2008;15:213-5.
    • (2008) Cell Death Differ , vol.15 , pp. 213-215
    • Callus, B.A.1    Ekert, P.G.2    Heraud, J.E.3
  • 26
    • 29244439933 scopus 로고    scopus 로고
    • Hypoxia-induced down-regulation of BRCA1 expression by E2Fs
    • Bindra RS, Gibson SL, Meng A, et al. Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res 2005;65:11597-604.
    • (2005) Cancer Res , vol.65 , pp. 11597-11604
    • Bindra, R.S.1    Gibson, S.L.2    Meng, A.3
  • 27
    • 42249093482 scopus 로고    scopus 로고
    • WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells
    • Cuddihy AR, Jalali F, Coackley C, Bristow RG. WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells. Mol Cancer Ther 2008;7:980-92.
    • (2008) Mol Cancer Ther , vol.7 , pp. 980-992
    • Cuddihy, A.R.1    Jalali, F.2    Coackley, C.3    Bristow, R.G.4
  • 28
    • 58149490629 scopus 로고    scopus 로고
    • Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity
    • Choudhury A, Zhao H, Jalali F, et al. Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity. Mol Cancer Ther 2009;8:203-13.
    • (2009) Mol Cancer Ther , vol.8 , pp. 203-213
    • Choudhury, A.1    Zhao, H.2    Jalali, F.3
  • 29
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce AJ, Johnson RD, Thompson LH, Jasin M. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev 1999;13:2633-8.
    • (1999) Genes Dev , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3    Jasin, M.4
  • 30
    • 78449302790 scopus 로고    scopus 로고
    • Cold Spring Harbor (NY): Cold Spring Harbor Laboratory
    • Transcriptional regulatory element database. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory; 2008.
    • (2008) Transcriptional Regulatory Element Database
  • 31
    • 57549089243 scopus 로고    scopus 로고
    • Using TESS to predict transcription factor binding sites in DNA sequence
    • Chapter 2:Unit 2.6
    • Schug J. Using TESS to predict transcription factor binding sites in DNA sequence. Curr Protoc Bioinformatics 2008;Chapter 2:Unit 2.6.
    • (2008) Curr Protoc Bioinformatics
    • Schug, J.1
  • 32
    • 0031860393 scopus 로고    scopus 로고
    • Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
    • Heinemeyer T, Wingender E, Reuter I, et al. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 1998;26:362-7.
    • (1998) Nucleic Acids Res , vol.26 , pp. 362-367
    • Heinemeyer, T.1    Wingender, E.2    Reuter, I.3
  • 33
    • 33845187907 scopus 로고    scopus 로고
    • Global mapping of c-Myc binding sites and target gene networks in human B cells
    • Zeller KI, Zhao X, Lee CW, et al. Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A 2006;103:17834-9.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17834-17839
    • Zeller, K.I.1    Zhao, X.2    Lee, C.W.3
  • 34
    • 9244234509 scopus 로고    scopus 로고
    • Defective DNA strand break repair after DNA damage in prostate cancer cells: Implications for genetic instability and prostate cancer progression
    • Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG. Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression. Cancer Res 2004;64:8526-33.
    • (2004) Cancer Res , vol.64 , pp. 8526-8533
    • Fan, R.1    Kumaravel, T.S.2    Jalali, F.3    Marrano, P.4    Squire, J.A.5    Bristow, R.G.6
  • 35
    • 0035542961 scopus 로고    scopus 로고
    • TGFβ and PTHrP control chondrocyte proliferation by activating cyclin D1 expression
    • Beier F, Ali Z, Mok D, et al. TGFβ and PTHrP control chondrocyte proliferation by activating cyclin D1 expression. Mol Biol Cell 2001; 12:3852-63.
    • (2001) Mol Biol Cell , vol.12 , pp. 3852-3863
    • Beier, F.1    Ali, Z.2    Mok, D.3
  • 36
    • 0036772554 scopus 로고    scopus 로고
    • Analysis of mouse Rad54 expression and its implications for homologous recombination
    • Amst
    • Essers J, Hendriks RW, Wesoly J, et al. Analysis of mouse Rad54 expression and its implications for homologous recombination. DNA Repair (Amst) 2002;1:779-93.
    • (2002) DNA Repair , vol.1 , pp. 779-793
    • Essers, J.1    Hendriks, R.W.2    Wesoly, J.3
  • 37
    • 0026605974 scopus 로고
    • Cyclin A is required in S phase in normal epithelial cells
    • Zindy F, Lamas E, Chenivesse X, et al. Cyclin A is required in S phase in normal epithelial cells. Biochem Biophys Res Commun 1992;182: 1144-54.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1144-1154
    • Zindy, F.1    Lamas, E.2    Chenivesse, X.3
  • 40
    • 41149113439 scopus 로고    scopus 로고
    • c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle
    • Wang H, Mannava S, Grachtchouk V, et al. c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle. Oncogene 2008;27:1905-15.
    • (2008) Oncogene , vol.27 , pp. 1905-1915
    • Wang, H.1    Mannava, S.2    Grachtchouk, V.3
  • 41
    • 34249028744 scopus 로고    scopus 로고
    • c-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-κB activity in pancreatic cancer cells
    • Biliran H, Jr., Banerjee S, Thakur A, et al. c-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-κB activity in pancreatic cancer cells. Clin Cancer Res 2007;13:2811-21.
    • (2007) Clin Cancer Res , vol.13 , pp. 2811-2821
    • Biliran Jr., H.1    Banerjee, S.2    Thakur, A.3
  • 42
    • 58149083526 scopus 로고    scopus 로고
    • Reversing cancer from inside and out: Oncogene addiction, cellular senescence, and the angiogenic switch
    • Felsher DW. Reversing cancer from inside and out: oncogene addiction, cellular senescence, and the angiogenic switch. Lymphat Res Biol 2008;6:149-54.
    • (2008) Lymphat Res Biol , vol.6 , pp. 149-154
    • Felsher, D.W.1
  • 44
    • 0025730938 scopus 로고
    • Modulation of cis-platinum resistance in Friend erythroleukemia cells by c-myc
    • Sklar MD, Prochownik EV. Modulation of cis-platinum resistance in Friend erythroleukemia cells by c-myc. Cancer Res 1991;51: 2118-23.
    • (1991) Cancer Res , vol.51 , pp. 2118-2123
    • Sklar, M.D.1    Prochownik, E.V.2
  • 45
    • 0035217986 scopus 로고    scopus 로고
    • Modification of the sensitivity to cisplatin with c-myc over-expression or down-regulation in colon cancer cells
    • Funato T, Kozawa K, Kaku M, Sasaki T. Modification of the sensitivity to cisplatin with c-myc over-expression or down-regulation in colon cancer cells. Anticancer Drugs 2001;12:829-34.
    • (2001) Anticancer Drugs , vol.12 , pp. 829-834
    • Funato, T.1    Kozawa, K.2    Kaku, M.3    Sasaki, T.4
  • 46
    • 61849158867 scopus 로고    scopus 로고
    • RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells
    • von Bueren AO, Shalaby T, Oehler-Janne C, et al. RNA interference- mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells. BMC Cancer 2009;9:10.
    • (2009) BMC Cancer , vol.9 , pp. 10
    • Von Bueren, A.O.1    Shalaby, T.2    Oehler-Janne, C.3
  • 47
    • 42249115685 scopus 로고    scopus 로고
    • The consequences of Rad51 overexpression for normal and tumor cells
    • Amst
    • Klein HL. The consequences of Rad51 overexpression for normal and tumor cells. DNA Repair (Amst) 2008;7:686-93.
    • (2008) DNA Repair , vol.7 , pp. 686-693
    • Klein, H.L.1


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