Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer

Cancer Gene Therapy

Volumn 11, Issue 1, 2004, Pages 52-60

  Ma, Nancy ^a,b   Szmitko, Paul ^a   Brade, Anthony ^a,b   Chu, Isabel ^b,c   Lo, Alex ^a   Woodgett, Jim ^a,b   Klamut, Henry ^a,b   Liu, Fei Fei ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Sunnybrook Health Sciences Centre   (Canada)

Author keywords

Adenovirus vectors; Breast; Cancer gene therapy; Hyperthermia; PKB

Indexed keywords

ADENOVIRUS VECTOR; MUTANT PROTEIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FORKHEAD; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER CELL CULTURE; CELL STRAIN MCF 7; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FETUS; GENE INSERTION; HEAT; HEAT SENSITIVITY; HEAT TREATMENT; HUMAN; HUMAN CELL; HYPERTHERMIA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; THERMAL EXPOSURE; VIRAL GENE THERAPY; VIRUS INFECTION;

ADENOVIRIDAE; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; GENE THERAPY; GENETIC VECTORS; GLYCOGEN SYNTHASE KINASE 3; HEAT; HUMANS; HYPERTHERMIA, INDUCED; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT;

ADENOVIRIDAE; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; INSERTION SEQUENCES; MINK CELL FOCUS-FORMING VIRUS;

EID: 0347986759     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700655     Document Type: Article

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