A facile 1,3-dipolar cycloaddition of azomethine ylides to 2-arylidene-1,3-indanediones: Synthesis of dispiro-oxindolylpyrrolothiazoles and their antimycobacterial evaluation

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 24, 2010, Pages 7278-7282

  Maheswari, Shanmugavel Uma ^a   Balamurugan, Kamaraj ^a   Perumal, Subbu ^a   Yogeeswari, Perumal ^b   Sriram, Dharmarajan ^b  

^a MADURAI KAMARAJ UNIVERSITY   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

1,3 Dipolar cycloaddition; 2 Arylidene 1,3 indanediones; Antitubercular activity; Azomethine ylide; Dispiro oxindolylpyrrolothiazoles; Mycobacterium tuberculosis

Indexed keywords

ANTIMYCOBACTERIAL AGENT; AZOMETHINE YLIDE; CARBOXYLIC ACID DERIVATIVE; CIPROFLOXACIN; ETHAMBUTOL; INDAN DERIVATIVE; ISATIN; SPIRO[5.3']5' NITROOXINDOLESPIRO [6.3''] 1H INDEN 1'',3''(2H) DIONE 7 (4 BROMOPHENYL)TETRAHYDRO 1H PYRROLO[1,2 C][1,3]THIAZOLE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CYCLOADDITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANTITUBERCULAR AGENTS; AZO COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; INDANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MYCOBACTERIUM TUBERCULOSIS; SPIRO COMPOUNDS; STEREOISOMERISM; THIAZOLES; THIOSEMICARBAZONES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 78449282828     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.10.080     Document Type: Article

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