A microwave-assisted, facile, regioselective Friedländer synthesis and antitubercular evaluation of 2,9-diaryl-2,3-dihydrothieno-[3,2-b]quinolines

European Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2010, Pages 682-688

  Balamurugan, Kamaraj ^a   Jeyachandran, Veerappan ^a   Perumal, Subbu ^a   Manjashetty, Thimmappa H ^b   Yogeeswari, Perumal ^b   Sriram, Dharmarajan ^b  

^a MADURAI KAMARAJ UNIVERSITY   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

2 Aminobenzophenone; 5 Aryldihydro 3(2H) thiophenone; Antimycobacterial activity; Friedl nder annulation; Multi drug resistant Mycobacterium tuberculosis; Mycobacterium tuberculosis; Thienoquinoline

Indexed keywords

2 (2,4 DICHLOROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 2 (3 NITROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 7 CHLORO 2 (2 CHLOROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 7 CHLORO 2 (2,4 DICHLOROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 7 CHLORO 2 (3 NITROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 7 CHLORO 2 (4 CHLOROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; 7 CHLORO 2 (4 FLUOROPHENYL) 9 PHENYL 2,3 DIHYDROTHIENO[3,2 B]QUINOLINE; CIPROFLOXACIN; ETHAMBUTOL; ISONIAZID; QUINOLINE DERIVATIVE; RIFAMPICIN; TRIFLUOROACETIC ACID; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANNULATION REACTION; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; FRIEDLANDER SYNTHESIS; IN VITRO STUDY; MICROWAVE RADIATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; TEMPERATURE;

ANTITUBERCULAR AGENTS; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MICROWAVES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; QUINOLINES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 73549093364     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.11.011     Document Type: Article

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