Exendin-4 protects oxidative stress-induced β-cell apoptosis through reduced JNK and GSK3β activity

Journal of Korean Medical Science

Volumn 25, Issue 11, 2010, Pages 1626-1632

  Kim, Ju Young ^a   Lim, Dong Mee ^a   Moon II, Chan ^b   Jo, Kyung Jin ^c   Lee, Seong Kyu ^c   Baik, Haing Woon ^c   Lee, Ki Ho ^c   Lee, Kang Woo ^a   Park, Keun Young ^a   Kim, Byung Joon ^a  

^a Konyang University   (South Korea)

^b Gachon University College of Medicine   (South Korea)

^c Eulji University School of Medicine   (South Korea)

Author keywords

Apoptosis; Exendin 4; Glucagon like peptide 1; Insulin secreting cells; Oxidative stress

Indexed keywords

CASPASE 3; CASPASE 9; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE RECEPTOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HYDROGEN PEROXIDE; INSULIN; PEPTIDE; STRESS ACTIVATED PROTEIN KINASE; VENOM;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; FLOW CYTOMETRY; GENETICS; HAMSTER; HUMAN; METABOLISM; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 9; CELLS, CULTURED; CRICETINAE; FLOW CYTOMETRY; GLUCAGON-LIKE PEPTIDE 1; GLYCOGEN SYNTHASE KINASE 3; HUMANS; HYDROGEN PEROXIDE; INSULIN; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PEPTIDES; PHOSPHORYLATION; RECEPTORS, GLUCAGON; SIGNAL TRANSDUCTION; VENOMS;

EID: 78449267308     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2010.25.11.1626     Document Type: Article

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