Silymarin, a natural antioxidant, protects cerebral cortex against manganese-induced neurotoxicity in adult rats

BioMetals

Volumn 23, Issue 6, 2010, Pages 985-996

  Chtourou, Yassine ^a   Fetoui, Hamadi ^a   Sefi, Mediha ^a   Trabelsi, Khaled ^b   Barkallah, Mohamed ^a   Boudawara, Tahia ^c   Kallel, Héla ^b   Zeghal, Najiba ^a  

^a UNIVERSITY OF SFAX   (Tunisia)

^b PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^c HABIB BOURGUIBA HOSPITAL   (Tunisia)

Author keywords

Cerebral cortex; Manganese toxicity; Oxidative stress; Silymarin

Indexed keywords

ACETYLCHOLINESTERASE; ADVANCED OXIDATION PROTEIN PRODUCT; ASCORBIC ACID; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MANGANESE CHLORIDE; NITRIC OXIDE; SILYMARIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN METABOLISM; RAT; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CEREBRAL CORTEX; CHLORIDES; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALE; MANGANESE COMPOUNDS; NEUROTOXICITY SYNDROMES; NITRITES; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; SILYMARIN; SUPEROXIDE DISMUTASE;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 78349312428     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10534-010-9345-x     Document Type: Article

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