Manganese induces oxidative impairment in cultured rat astrocytes

Toxicological Sciences

Volumn 98, Issue 1, 2007, Pages 198-205

  Milatovic, Dejan ^a   Yin, Zhaobao ^a   Gupta, Ramesh C ^b   Sidoryk, Marta ^c   Albrecht, Jan ^c   Aschner, Judy L ^a   Aschner, Michael ^a,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MURRAY STATE UNIVERSITY   (United States)

^c MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

m; Astrocyte; ATP; F2 isoprostanes; Glutamine; Manganese; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ASCT2 PROTEIN; CARRIER PROTEIN; GLUTAMIC ACID; GLUTAMINE; GLUTAMINE TRANSPORTER; ISOPROSTANE DERIVATIVE; MANGANESE; MESSENGER RNA; SNAT1 PROTEIN; SNAT3 PROTEIN; TETRAMETHYLRHODAMINE ETHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POTENTIOMETRY; QUANTITATIVE ANALYSIS; RAT;

ADENOSINE TRIPHOSPHATE; AMINO ACID TRANSPORT SYSTEM ASC; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; EXTRACELLULAR SPACE; F2-ISOPROSTANES; GLUTAMINE; L-LACTATE DEHYDROGENASE; MANGANESE POISONING; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES;

RATTUS;

EID: 34447581172     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm095     Document Type: Article

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