Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells

Brain Research

Volumn 897, Issue 1-2, 2001, Pages 175-179

  Zheng, Wei ^a,b   Zhao, Qiuqu ^a  

^a Columbia University ^*  (United States)

^b New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

Astrocyte; Iron; Manganese; PC12 cell; Transferrin receptor; Transferrin receptor mRNA; Uptake

Indexed keywords

ACONITATE HYDRATASE; IRON; IRON 59; MANGANESE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRAIN; CYTOTOXICITY; ENZYME ACTIVITY; EXPOSURE; GLIA CELL; HOMEOSTASIS; INTOXICATION; IRON OVERLOAD; IRON TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ASTROCYTES; GENE EXPRESSION; HOMEOSTASIS; IRON; IRON OVERLOAD; IRON RADIOISOTOPES; MANGANESE; NEURONS; PC12 CELLS; RATS; RECEPTORS, TRANSFERRIN; RNA, MESSENGER;

EID: 0035815544     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02049-2     Document Type: Article

References (21)

1. Manganese poisoning and the attack of trivalent manganese upon catecholamines
2. Manganese uptake and efflux in cultured rat astrocytes
3. Manganese uptake and distribution in the central nervous system (CNS)
4. Aconitase, a two-faced protein: Enzyme and iron regulatory factor
5. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
6. Altered cellular distribution of iron in the central nervous system of myelin deficient rats
7. Differentiation of astrocytes and oligodendrocytes from germinal matrix cells in primary culture
8. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
9. Iron regulatory proteins 1 and 2
10. New insights into the cause of Parkinson's disease
11. Regulating the fate of mRNA: The control of cellular iron metabolism
12. Immunohistochemical localization of intraneuronal transferrin receptor immunoreactivity in the adult mouse central nervous system
13. Determinants of reactivity in metal toxicology
14. Characterization of rat transferrin receptor cDNA: The regulation of transferrin receptor mRNA in testes and in Sertoli cells in culture
15. Protein oxidation and aging
16. Glutamine synthetase: The major Mn (II) enzyme in mammalian brain
17. The possible role of iron in the etiopathology of Parkinson's disease
18. Manganese inhibits mitochondrial aconitase: A mechanism of manganese neurotoxicity
19. Alteration of iron homeostasis following chronic exposure to manganese in rats
20. Comparative toxicokinetics of manganese chloride and methylcyclo-pentadienyl manganese tricarbonyl (MMT) in male Sprague-Dawley rats