CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity

Circulation Research

Volumn 107, Issue 9, 2010, Pages 1083-1093

  Cheng, Min ^a,b   Zhou, Junlan ^a   Wu, Min ^a,d   Boriboun, Chan ^a   Thorne, Tina ^a   Liu, Ting ^a   Xiang, Zhifu ^b,d   Zeng, Qiutang ^f   Tanaka, Toshikazu ^a   Tang, Yao Liang ^e   Kishore, Raj ^a   Tomasson, Michael H ^c   Miller, Richard J ^a   Losordo, Douglas W ^a   Qin, Gangjian ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Union Hospital   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

bone marrow; c kit; CXCR4; mobilization; stem cells

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; PLERIXAFOR; STEM CELL FACTOR; STEROID RECEPTOR COACTIVATOR 1; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL CULTURE; CELL FUNCTION; CELL INTERACTION; CELL MIGRATION; ENZYME ACTIVITY; GENE DELETION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; MALE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION;

ANIMALS; BONE MARROW CELLS; CELL LINE; CELL MOVEMENT; CHEMOKINE CXCL12; ENZYME ACTIVATION; HETEROCYCLIC COMPOUNDS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTORS, CXCR4; SRC-FAMILY KINASES; STEM CELLS;

EID: 78349309965     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.220970     Document Type: Article

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