-
1
-
-
0346780250
-
Directed evolution of enzymes: New biocatalysts for asymmetric synthesis
-
Alexeeva M, Carr R and Turner N J 2003 Directed evolution of enzymes: new biocatalysts for asymmetric synthesis Org. Biomol. Chem. 1 4133-7
-
(2003)
Org. Biomol. Chem.
, vol.1
, pp. 4133-4137
-
-
Alexeeva, M.1
Carr, R.2
Turner, N.J.3
-
2
-
-
0029055551
-
Isolation of high-affinity RNA ligands to HIV-1 integrase from a random pool
-
Allen P, Worland S and Gold L 1995 Isolation of high-affinity RNA ligands to HIV-1 integrase from a random pool Virology 209 327-36
-
(1995)
Virology
, vol.209
, pp. 327-336
-
-
Allen, P.1
Worland, S.2
Gold, L.3
-
3
-
-
1842429724
-
In vitro selection of DNA aptamers on chips using a method for generating point mutations
-
London: Taylor and Francis
-
Asai R, Nishimura S I, Aita T and Takahashi K 2005 In vitro selection of DNA aptamers on chips using a method for generating point mutations Analytical Letters (London: Taylor and Francis) pp 645-56
-
(2005)
Analytical Letters
, pp. 645-656
-
-
Asai, R.1
Nishimura, S.I.2
Aita, T.3
Takahashi, K.4
-
5
-
-
67649982744
-
Diversity and complexity in DNA recognition by transcription factors
-
Badis G et al 2009 Diversity and complexity in DNA recognition by transcription factors Science 324 1720-3
-
(2009)
Science
, vol.324
, pp. 1720-1723
-
-
Badis, G.1
-
8
-
-
0035478854
-
Random forests
-
Breiman L 2001 Random forests Mach. Learn. 45 5-32
-
(2001)
Mach. Learn
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
10
-
-
0002796814
-
Understanding interactions among genetic algorithm parameters
-
Deb K and Agrawal S 1999 Understanding interactions among genetic algorithm parameters Found. Genet. Algorithms 5 265-86
-
(1999)
Found. Genet. Algorithms
, vol.5
, pp. 265-286
-
-
Deb, K.1
Agrawal, S.2
-
11
-
-
77649260489
-
Reengineering orthogonally selective riboswitches
-
Dixon N, Duncan J N, Geerlings T, Dunstan M S, McCarthy J E G, Leys D and Micklefield J 2010 Reengineering orthogonally selective riboswitches Proc. Natl Acad. Sci. USA 107 2830-5
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2830-2835
-
-
Dixon, N.1
Duncan, J.N.2
Geerlings, T.3
Dunstan, M.S.4
McCarthy, J.E.G.5
Leys, D.6
Micklefield, J.7
-
12
-
-
0003309776
-
On evolutionary exploration and exploitation
-
Eiben A E and Schippers C A 1998 On evolutionary exploration and exploitation Fundam. Inform. 35 35-50
-
(1998)
Fundam. Inform.
, vol.35
, pp. 35-50
-
-
Eiben, A.E.1
Schippers, C.A.2
-
13
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington A D and Szostak J W 1990 In vitro selection of RNA molecules that bind specific ligands Nature 346 818-22
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
14
-
-
33947095042
-
Improving catalytic function by ProSAR-driven enzyme evolution
-
Fox R J et al 2007 Improving catalytic function by ProSAR-driven enzyme evolution Nat. Biotechnol. 25 338-44
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 338-344
-
-
Fox, R.J.1
-
18
-
-
0033930772
-
Replicability and recurrence in the experimental evolution of a group I ribozyme
-
Hanczyc M M and Dorit R L 2000 Replicability and recurrence in the experimental evolution of a group I ribozyme Mol. Biol. Evol. 17 1050-60
-
(2000)
Mol. Biol. Evol.
, vol.17
, pp. 1050-1060
-
-
Hanczyc, M.M.1
Dorit, R.L.2
-
19
-
-
0003463297
-
An introduction with application to biology, control and artificial intelligence
-
Cambridge, MA: MIT Press
-
Holland J H 1975 An introduction with application to biology, control and artificial intelligence Adaptation in Natural and Artificial System (Cambridge, MA: MIT Press)
-
(1975)
Adaptation in Natural and Artificial System
-
-
Holland, J.H.1
-
21
-
-
84897557400
-
Fitness uniform selection to preserve genetic diversity
-
Hutter M 2002 Fitness uniform selection to preserve genetic diversity E-Commerce Technology, IEEE Int. Conf. pp 783-8
-
(2002)
E-Commerce Technology, IEEE Int. Conf.
, pp. 783-788
-
-
Hutter, M.1
-
23
-
-
3042732096
-
Directed evolution of nucleic acid enzymes
-
Joyce G F 2004 Directed evolution of nucleic acid enzymes Annu. Rev. Biochem. 73 791-836
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 791-836
-
-
Joyce, G.F.1
-
24
-
-
38049048268
-
Exploring the sequence space of a DNA aptamer using microarrays
-
Katilius E, Flores C and Woodbury N W 2007 Exploring the sequence space of a DNA aptamer using microarrays Nucleic Acids Res. 35 7626-35
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7626-7635
-
-
Katilius, E.1
Flores, C.2
Woodbury, N.W.3
-
25
-
-
0023647382
-
Towards a general-theory of adaptive walks on rugged landscapes
-
Kauffman S and Levin S 1987 Towards a general-theory of adaptive walks on rugged landscapes J. Theor. Biol. 128 11-45
-
(1987)
J. Theor. Biol.
, vol.128
, pp. 11-45
-
-
Kauffman, S.1
Levin, S.2
-
26
-
-
33751356224
-
Systems biology, metabolic modelling and metabolomics in drug discovery and development
-
Kell D B 2006 Systems biology, metabolic modelling and metabolomics in drug discovery and development Drug Discov. Today 11 1085-92
-
(2006)
Drug Discov. Today
, vol.11
, pp. 1085-1092
-
-
Kell, D.B.1
-
27
-
-
58549109637
-
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape
-
Knight C G, Platt M, Rowe W, Wedge D C, Khan F, Day P J, McShea A, Knowles J and Kell D B 2009 Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape Nucleic Acids Res. 37 e6
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Knight, C.G.1
Platt, M.2
Rowe, W.3
Wedge, D.C.4
Khan, F.5
Day, P.J.6
McShea, A.7
Knowles, J.8
Kell, D.B.9
-
28
-
-
78649310027
-
From aptamer-based biomarker discovery to diagnostic and clinical applications: An aptamer-based, streamlined multiplex proteomic assay available from
-
Kraemer S et al 2010 From aptamer-based biomarker discovery to diagnostic and clinical applications: an aptamer-based, streamlined multiplex proteomic assay available from Nature Precedings http://hdl.handle.net/10101/npre.2010. 4642.1
-
(2010)
Nature Precedings
-
-
Kraemer, S.1
-
29
-
-
36448991500
-
Clustal W and Clustal X
-
version 2.0
-
Larkin M A et al 2007 Clustal W and Clustal X version 2.0 Bioinformatics 23 2947-8
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
-
30
-
-
1142277795
-
Assessing the likelihood of recurrence during RNA evolution in vitro
-
Lehman N 2004 Assessing the likelihood of recurrence during RNA evolution in vitro Artif. Life 10 1-22
-
(2004)
Artif. Life
, vol.10
, pp. 1-22
-
-
Lehman, N.1
-
31
-
-
84934438960
-
UNAFold: Software for nucleic acid folding and hybridization
-
Markham N R and Zuker M 2008 UNAFold: software for nucleic acid folding and hybridization Methods Mol. Biol. 453 3-31
-
(2008)
Methods Mol. Biol.
, vol.453
, pp. 3-31
-
-
Markham, N.R.1
Zuker, M.2
-
32
-
-
0014935646
-
Natural selection and the concept of a protein space
-
Maynard Smith J 1970 Natural selection and the concept of a protein space Nature 225 563-4
-
(1970)
Nature
, vol.225
, pp. 563-564
-
-
Maynard Smith, J.1
-
34
-
-
0002091030
-
How genetic algorithms really work: I. Mutation and hillclimbing
-
Mühlenbein H 1992 How genetic algorithms really work: I. Mutation and hillclimbing Parallel Problem Solving from Nature vol 2 pp 15-25
-
(1992)
Parallel Problem Solving From Nature
, vol.2
, pp. 15-25
-
-
Mühlenbein, H.1
-
35
-
-
0014757386
-
A general method applicable to the search for similarities in the amino acid sequence of two proteins
-
Needleman S B and Wunsch C D 1970 A general method applicable to the search for similarities in the amino acid sequence of two proteins J. Mol. Biol. 48 443-53
-
(1970)
J. Mol. Biol.
, vol.48
, pp. 443-453
-
-
Needleman, S.B.1
Wunsch, C.D.2
-
36
-
-
57349117629
-
Assessment of additive/nonadditive effects in structure-activity relationships: Implications for iterative drug design
-
Patel Y, Gillet V J, Howe T, Pastor J, Oyarzabal J and Willett P 2008 Assessment of additive/nonadditive effects in structure-activity relationships: implications for iterative drug design J. Med. Chem. 51 7552-62
-
(2008)
J. Med. Chem.
, vol.51
, pp. 7552-7562
-
-
Patel, Y.1
Gillet, V.J.2
Howe, T.3
Pastor, J.4
Oyarzabal, J.5
Willett, P.6
-
37
-
-
65849401380
-
Analysis of aptamer sequence activity relationships
-
Platt M, Rowe W, Knowles J, Day P J and Kell D B 2009 Analysis of aptamer sequence activity relationships Integr. Biol. 1 116-22
-
(2009)
Integr. Biol.
, vol.1
, pp. 116-122
-
-
Platt, M.1
Rowe, W.2
Knowles, J.3
Day, P.J.4
Kell, D.B.5
-
38
-
-
65849377316
-
Aptamer evolution for array-based diagnostics
-
Platt M, Rowe W, Wedge D C, Kell D B, Knowles J and Day P J 2009 Aptamer evolution for array-based diagnostics Anal. Biochem. 390 203-5
-
(2009)
Anal. Biochem.
, vol.390
, pp. 203-205
-
-
Platt, M.1
Rowe, W.2
Wedge, D.C.3
Kell, D.B.4
Knowles, J.5
Day, P.J.6
-
39
-
-
33846551980
-
Empirical fitness landscapes reveal accessible evolutionary paths
-
Poelwijk F J, Kiviet D J, Weinreich D M and Tans S J 2007 Empirical fitness landscapes reveal accessible evolutionary paths Nature 445 383-6
-
(2007)
Nature
, vol.445
, pp. 383-386
-
-
Poelwijk, F.J.1
Kiviet, D.J.2
Weinreich, D.M.3
Tans, S.J.4
-
40
-
-
70450242805
-
Exploring protein fitness landscapes by directed evolution
-
Romero P A and Arnold F H 2009 Exploring protein fitness landscapes by directed evolution Nat. Rev. Mol. Cell Biol. 10 866-76
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, pp. 866-876
-
-
Romero, P.A.1
Arnold, F.H.2
-
41
-
-
0041324888
-
A comparison of directed evolution approaches using the beta-glucuronidase model system
-
Rowe L A, Geddie M L, Alexander O B and Matsumura I 2003 A comparison of directed evolution approaches using the beta-glucuronidase model system J. Mol. Biol. 332 851-60
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 851-860
-
-
Rowe, L.A.1
Geddie, M.L.2
Alexander, O.B.3
Matsumura, I.4
-
42
-
-
77949312446
-
Advances and perspectives in aptamer arrays
-
Rowe W, Platt M and Day P J 2009 Advances and perspectives in aptamer arrays Integr. Biol. 1 53-8
-
(2009)
Integr. Biol.
, vol.1
, pp. 53-58
-
-
Rowe, W.1
Platt, M.2
Day, P.J.3
-
43
-
-
84944486544
-
Prediction and entropy of printed English
-
Shannon C E 1951 Prediction and entropy of printed English Bell Syst. Tech. J. 30 50-64
-
(1951)
Bell Syst. Tech. J.
, vol.30
, pp. 50-64
-
-
Shannon, C.E.1
-
44
-
-
0028110130
-
DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution
-
Stemmer W P 1994 DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution Proc. Natl Acad. Sci. USA 91 10747-51
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10747-10751
-
-
Stemmer, W.P.1
-
45
-
-
0002881568
-
Uniform crossover in genetic algorithms
-
George Mason University, USA, San Mateo, CA: Morgan Kaufmann Publishers
-
Sywerda G 1989 Uniform crossover in genetic algorithms Proc. 3rd Int. Conf. on Genetic Algorithms, George Mason University, USA (San Mateo, CA: Morgan Kaufmann Publishers)
-
(1989)
Proc. 3rd Int. Conf. on Genetic Algorithms
-
-
Sywerda, G.1
-
46
-
-
0036137323
-
A higher-order background model improves the detection of promoter regulatory elements by Gibbs sampling
-
Thijs G, Lescot M, Marchal K, Rombauts S, De Moor B, Rouze P and Moreau Y 2001 A higher-order background model improves the detection of promoter regulatory elements by Gibbs sampling Bioinformatics 17 1113-22
-
(2001)
Bioinformatics
, vol.17
, pp. 1113-1122
-
-
Thijs, G.1
Lescot, M.2
Marchal, K.3
Rombauts, S.4
De Moor, B.5
Rouze, P.6
Moreau, Y.7
-
47
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk C and Gold L 1990 Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249 505-10
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
48
-
-
0033770580
-
Rational evolutionary design: The theory of in vitro protein evolution
-
Voigt C A, Kauffman S and Wang Z G 2000 Rational evolutionary design: the theory of in vitro protein evolution Adv. Protein Chem. 55 79-160
-
(2000)
Adv. Protein Chem.
, vol.55
, pp. 79-160
-
-
Voigt, C.A.1
Kauffman, S.2
Wang, Z.G.3
-
49
-
-
59649088235
-
In silico modelling of directed evolution: Implications for experimental design and stepwise evolution
-
Wedge D C, Rowe W, Kell D B and Knowles J 2009 In silico modelling of directed evolution: implications for experimental design and stepwise evolution J. Theor. Biol. 257 131-41
-
(2009)
J. Theor. Biol.
, vol.257
, pp. 131-141
-
-
Wedge, D.C.1
Rowe, W.2
Kell, D.B.3
Knowles, J.4
-
50
-
-
12144282243
-
Directed evolution of enzymes for biocatalysis and the life sciences
-
Williams G J, Nelson A S and Berry A 2004 Directed evolution of enzymes for biocatalysis and the life sciences Cell. Mol. Life Sci. 61 3034-46
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 3034-3046
-
-
Williams, G.J.1
Nelson, A.S.2
Berry, A.3
-
52
-
-
19344368565
-
Screening and characterization of aptamers of hepatitis C virus NS3 helicase
-
Zhan L-S, Zhuo H-L and Wang H-Z 2005 Screening and characterization of aptamers of hepatitis C virus NS3 helicase Prog. Biochem. Biophys. 32 245-50
-
(2005)
Prog. Biochem. Biophys.
, vol.32
, pp. 245-250
-
-
Zhan, L.-S.1
Zhuo, H.-L.2
Wang, H.-Z.3
-
53
-
-
77949405042
-
A light-driven DNA nanomachine for the efficient photoswitching of RNA digestion
-
Zhou M G, Liang X G, Mochizuki T and Asanuma H 2010 A light-driven DNA nanomachine for the efficient photoswitching of RNA digestion Angew. Chem., Int. Ed. 49 2167-70
-
(2010)
Angew. Chem., Int. Ed.
, vol.49
, pp. 2167-2170
-
-
Zhou, M.G.1
Liang, X.G.2
Mochizuki, T.3
Asanuma, H.4
|