Melatonin reduces hyperalgesia associated with inflammation

Journal of Pineal Research

Volumn 49, Issue 4, 2010, Pages 321-331

  Esposito, Emanuela ^a,b   Paterniti, Irene ^b   Mazzon, Emanuela ^a   Bramanti, Placido ^a   Cuzzocrea, Salvatore ^a,b  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

antinociceptive activity; hyperalgesia; melatonin; mitogen activated protein kinases; NF kB

Indexed keywords

3 NITROTYROSINE; CYCLOOXYGENASE 2; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PEROXYNITRITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HYPERALGESIA; INFLAMMATION; MALE; NITRATION; NONHUMAN; PAW EDEMA; PROTEIN EXPRESSION; RAT; TISSUE INJURY;

ANIMALS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELATONIN; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PEROXYNITROUS ACID; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; SUPEROXIDES; TYROSINE;

EID: 78349278027     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00796.x     Document Type: Article

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