Synthesis, antimicrobial evaluation, and docking studies of novel 4-substituted quinazoline derivatives as DNA-gyrase inhibitors

Archiv der Pharmazie

Volumn 343, Issue 10, 2010, Pages 570-576

  Boyapati, Shireesha ^a   Kulandaivelu, Umasankar ^a   Sangu, Srinivas ^a   Vanga, Malla Reddy ^a  

^a Vaagdevi College of Pharmacy   (India)

Author keywords

4 Substituted quinazolines; Antimicrobial activity; DNA Gyrase inhibitors

Indexed keywords

1,3 BENZOXAZIN 4 ONE; 4 (1,3,4 OXADIAZOL 2 YLMETHOXY) 2 PHENYLQUINAZOLINE; 4 QUINAZOLINONE; 5 [[(2 PHENYLQUINAZOLIN 4 YL)OXY]METHYL]1,3,4 OXADIAZOL 2(3H)THIONE; 5 [[(6 BROMO 2 PHENYLQUINAZOLIN 4 YL)OXY]METHYL] 1,3,4 OXADIAZOL 2(3H)THIONE; 6 BROMO 4 (1,3,4 OXADIAZOL 2 YLMETHOXY) 2 PHENYLQUINAZOLINE; [(2 PHENYL 4 QUINAZOLINYL) OXY]ACETYL 3 METHYL PYRAZOL 5 ONE; [(2 PHENYL 4 QUINAZOLINYL)OXY]ACETYL HYDRAZINE; [(2 PHENYL 6 BROMO 4 QUINAZOLINYL)OXY]ACETYL 3 METHYLPYRAZOL 5 ONE; [(6 BROMO 2 PHENYL 4 QUINAZOLINYL)OXY]ACETYL HYDRAZINE; AMPHOTERICIN B; ANTHRANILIC ACID; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CIPROFLOXACIN; GYRASE INHIBITOR; OXADIAZOLYL METHYLOXY QUINAZOLINE; PYRAZOLYL ACETOXY METHYL QUINAZOLINE; QUINAZOLINE DERIVATIVE; QUINAZOLINYL 4 OXY ETHYLACETATE; QUINAZOLINYL 4 OXYACETYL HYDRAZINE; TRIAZOLYLMETHYLOXY QUINAZOLINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; BACILLUS SUBTILIS; CANDIDA ALBICANS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; ESCHERICHIA COLI; HYDROGEN BOND; IN VITRO STUDY; INFRARED RADIATION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; SUBSTITUTION REACTION;

ANTHRANILIC ACIDS; ANTI-INFECTIVE AGENTS; BACTERIA; DNA GYRASE; DRUG RESISTANCE, MICROBIAL; ENZYME INHIBITORS; FUNGI; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; QUINAZOLINES; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78349269505     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201000065     Document Type: Article

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