Some new 2,3,6-trisubstituted quinazolinones as potent anti-inflammatory, analgesic and COX-II inhibitors

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 23, 2003, Pages 5293-5299

  Kumar, Ashok ^a   Sharma, Shalabh ^a   Archana, ^a   Bajaj, Kiran ^a   Sharma, Shipra ^a   Panwar, Hemant ^a   Singh, Tripti ^a   Srivastava, V K ^a  

^a LLRM MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 CHLOROPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (2'' METHYLINDOL 3'' YL) 4(3H) QUINAZOLINONE; 2 (2 CHLOROPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 4(3H) QUINAZOLINONE; 2 (2 CHLOROPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 6 BROMO 4(3H) QUINAZOLINONE; 2 (2 METHOXYPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (INDOL 3'' YL) 4(3H) QUINAZOLINONE; 2 (2 METHOXYPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (INDOL 3'' YL) 6 IODO 4(3H) QUINAZOLINONE; 2 (2 METHOXYPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 4(3H) QUINAZOLINONE; 2 (2 METHOXYPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (INDOL 3' YL) 6 IODO 4(3H) QUINAZOLINONE; 2 (4 CHLOROPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (INDOL 3'' YL) 6 IODO 4(3H) QUINAZOLINONE; 2 (4 DIMETHYLAMINOPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (2'' METHYLINDOL 3' YL) 6 BROMO 4(3H) QUINAZOLINONE; 2 (4 DIMETHYLAMINOPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 6 BROMO 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (2'' METHYLINDOL 3'' YL) 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (2'' METHYLINDOL 3'' YL) 6 BROMO 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLAMINOMETHYLACETYL 4' OXO 1' THIAZOLIDINYL) 3 (INDOL 3'' YL) 6 IODO 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (2' METHYLINDOL 3' YL) 6 BROMO 4(3H) QUINAZOLINONE; 2 (4 METHOXYPHENYLMETHYLENEIMINO)AMINOACETYLMETHYLENE 3 (INDOL 3' YL) 6 IODO 4(3H) QUINAZOLINONE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CARBON; CYCLOOXYGENASE 2 INHIBITOR; HYDROGEN; INDOMETACIN; NITROGEN; PHENYLBUTAZONE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; INFRARED SPECTROMETRY; LETHAL DOSE; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ANALYSIS; ULCEROGENESIS;

EID: 0242298226     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00501-7     Document Type: Article

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