Melatonin inhibits postischemic matrix metalloproteinase-9 (MMP-9) activation via dual modulation of plasminogen/plasmin system and endogenous MMP inhibitor in mice subjected to transient focal cerebral ischemia

Journal of Pineal Research

Volumn 49, Issue 4, 2010, Pages 332-341

  Tai, Shih Huang ^a   Chen, Hung Yi ^a,b   Lee, E Jian ^a   Chen, Tsung Ying ^a,c   Lin, Hsiao Wen ^a   Hung, Yu Chang ^a   Huang, Sheng Yang ^a   Chen, Ying Hsin ^a   Lee, Wei Ting ^a   Wu, Tian Shung ^a,b,d  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

matrix metalloproteinase; melatonin; plasminogen plasmin system; stroke; tissue inhibitor of metalloproteinases

Indexed keywords

CASEIN; GELATIN; GELATINASE A; GELATINASE B; LAMININ; MELATONIN; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN PROTECTION; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; MALE; MIDDLE CEREBRAL ARTERY; MOUSE; NONHUMAN; PRESERVATION; PROTEIN EXPRESSION; REPERFUSION; TRANSIENT ISCHEMIC ATTACK; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBRINOLYSIN; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELATONIN; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 78349240002     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00797.x     Document Type: Article

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