-
1
-
-
0032904412
-
An evaluation of the role of mitochondria in neurodegenerative disease: Mitochondrial mutations and oxidative pathology, protective nuclear response, and cell death in neurodegeneration
-
CASSARINO DS, BENNETT JP, Jr. An evaluation of the role of mitochondria in neurodegenerative disease: mitochondrial mutations and oxidative pathology, protective nuclear response, and cell death in neurodegeneration. Brain Res Rev 1999; 29:1-25.
-
(1999)
Brain Res Rev
, vol.29
, pp. 1-25
-
-
Cassarino, D.S.1
Bennett Jr., J.P.2
-
2
-
-
0037417220
-
Apoptosis and caspases in neurodegenerative diseases
-
FRIEDLANDER RM. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 2003; 348:1365-1375.
-
(2003)
N Engl J Med
, vol.348
, pp. 1365-1375
-
-
Friedlander, R.M.1
-
3
-
-
0242364751
-
Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats
-
NISHIDA S, SATO R, MURAI I et al. Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats. J Pineal Res 2003; 35:251-256.
-
(2003)
J Pineal Res
, vol.35
, pp. 251-256
-
-
Nishida, S.1
Sato, R.2
Murai, I.3
-
4
-
-
13744255848
-
Retinal network adaptation to bright light requires tyrosinase
-
PAGE-MCCAW PS, CHUNG SC, MUTO A et al. Retinal network adaptation to bright light requires tyrosinase. Nat Neurosci 2004; 7:1329-1336.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1329-1336
-
-
Page-Mccaw, P.S.1
Chung, S.C.2
Muto, A.3
-
5
-
-
0002979059
-
Melatonin: A potent, endogenous hydroxyl radical scavenger
-
TAN DX, CHEN LD, POEGGELER B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1993; 1:57-60.
-
(1993)
Endocr J
, vol.1
, pp. 57-60
-
-
Tan, D.X.1
Chen, L.D.2
Poeggeler, B.3
-
6
-
-
1242314788
-
Caspase-3 and heat shock protein-70 in rat liver treated with aflatoxin B1: Effect of melatonin
-
MEKI AR, ESMAIL EEL D, HUSSEIN AA et al. Caspase-3 and heat shock protein-70 in rat liver treated with aflatoxin B1: effect of melatonin. Toxicon 2004; 43:93-100.
-
(2004)
Toxicon
, vol.43
, pp. 93-100
-
-
Meki, A.R.1
Esmail Eel, D.2
Hussein, A.A.3
-
7
-
-
22044448363
-
+-induced mitochondrial DNA oxidative damage in vivo and in vitro
-
+-induced mitochondrial DNA oxidative damage in vivo and in vitro. J Pineal Res 2005; 39:34-42.
-
(2005)
J Pineal Res
, vol.39
, pp. 34-42
-
-
Chen, L.J.1
Gao, Y.Q.2
Li, X.J.3
-
8
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
-
BLUM D, TORCH S, LAMBENG N et al. Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 2001; 65:135-172.
-
(2001)
Prog Neurobiol
, vol.65
, pp. 135-172
-
-
Blum, D.1
Torch, S.2
Lambeng, N.3
-
9
-
-
0033782296
-
Mitochondrial participation in ischemic and traumatic neural cell death
-
FISKUM G. Mitochondrial participation in ischemic and traumatic neural cell death. J Neurotrauma 2000; 17:843-855.
-
(2000)
J Neurotrauma
, vol.17
, pp. 843-855
-
-
Fiskum, G.1
-
10
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
CHAN PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 2001; 21:2-14.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
11
-
-
0040204710
-
Study of gene regulation by NF-kappa B and AP-1 in response to reactive oxygen intermediates
-
MULLER JM, RUPEC RA, BAEUERLE PA. Study of gene regulation by NF-kappa B and AP-1 in response to reactive oxygen intermediates. Methods 1997; 11:301-312.
-
(1997)
Methods
, vol.11
, pp. 301-312
-
-
Muller, J.M.1
Rupec, R.A.2
Baeuerle, P.A.3
-
12
-
-
0036260697
-
Cellular response to oxidative stress: Signaling for suicide and survival
-
MARTINDALE JL, HOLBROOK NJ. Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 2002; 192:1-15.
-
(2002)
J Cell Physiol
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
13
-
-
1342268351
-
Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1
-
BENI SM, KOHEN R, REITER RJ et al. Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J 2004; 18:149-151.
-
(2004)
FASEB J
, vol.18
, pp. 149-151
-
-
Beni, S.M.1
Kohen, R.2
Reiter, R.J.3
-
14
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
BAEUERLE PA, HENKEL T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994; 12:141-179.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
15
-
-
0036805108
-
Signaling from toxic metals to NF-kappaB and beyond: Not just a matter of reactive oxygen species
-
CHEN F, SHI X. Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species. Environ Health Perspect 2002; 110:807-811.
-
(2002)
Environ Health Perspect
, vol.110
, pp. 807-811
-
-
Chen, F.1
Shi, X.2
-
17
-
-
0032409781
-
Bcl-2 family proteins
-
REED JC. Bcl-2 family proteins. Oncogene 1998; 17:3225-3236.
-
(1998)
Oncogene
, vol.17
, pp. 3225-3236
-
-
Reed, J.C.1
-
18
-
-
14344254373
-
Melatonin prevents hydrogen peroxide-induced Bax expression in cultured rat astrocytes
-
JUKNAT AA, MENDEZ MDEL V, QUAGLINO A et al. Melatonin prevents hydrogen peroxide-induced Bax expression in cultured rat astrocytes. J Pineal Res 2005; 38:84-92.
-
(2005)
J Pineal Res
, vol.38
, pp. 84-92
-
-
Juknat, A.A.1
Mendez, M.D.V.2
Quaglino, A.3
-
19
-
-
3343017533
-
Oxidative stress: A theoretical model or a biological reality?
-
SORG O. Oxidative stress: a theoretical model or a biological reality? C R Biol 2004; 327:649-662.
-
(2004)
C R Biol
, vol.327
, pp. 649-662
-
-
Sorg, O.1
-
20
-
-
0036262303
-
Antioxidant therapy in acute central nervous system injury: Current state
-
GILGUN-SHERKI Y, ROSENBAUM Z, MELAMED E et al. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol Rev 2002; 54:271-284.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 271-284
-
-
Gilgun-Sherki, Y.1
Rosenbaum, Z.2
Melamed, E.3
-
21
-
-
0037237927
-
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
-
ISCHIROPOULOS H, BECKMAN JS. Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 2003; 111:163-169.
-
(2003)
J Clin Invest
, vol.111
, pp. 163-169
-
-
Ischiropoulos, H.1
Beckman, J.S.2
-
22
-
-
0026484388
-
The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
-
FAHN S, COHEN G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 1992; 32:804-812.
-
(1992)
Ann Neurol
, vol.32
, pp. 804-812
-
-
Fahn, S.1
Cohen, G.2
-
23
-
-
0037085072
-
2), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors
-
2), caspase-3, and nuclear factor kappa-B (NF-kappaB), p53, c-Jun transcription factors. Biochem Pharmacol 2002; 63:677-688.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 677-688
-
-
Del Rio, M.J.1
Velez-Pardo, C.2
-
24
-
-
0034672108
-
Evidence of prooxidant and antioxidant action of melatonin on human liver cell line HepG2
-
OSSENI RA, RAT P, BOGDAN A et al. Evidence of prooxidant and antioxidant action of melatonin on human liver cell line HepG2. Life Sci 2000; 68:387-399.
-
(2000)
Life Sci
, vol.68
, pp. 387-399
-
-
Osseni, R.A.1
Rat, P.2
Bogdan, A.3
-
25
-
-
0034564392
-
Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
-
TAN DX, MANCHESTER LC, REITER RJ et al. Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free Radic Biol Med 2000; 29:1177-1185.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 1177-1185
-
-
Tan, D.X.1
Manchester, L.C.2
Reiter, R.J.3
-
26
-
-
1642562820
-
Regulation of antioxidant enzymes: A significant role for melatonin
-
RODRIGUEZ C, MAYO JC, SAINZ RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36:1-9.
-
(2004)
J Pineal Res
, vol.36
, pp. 1-9
-
-
Rodriguez, C.1
Mayo, J.C.2
Sainz, R.M.3
-
27
-
-
23744513206
-
A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes
-
TOMAS-ZAPICO C, COTO-MONTES A. A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes. J Pineal Res 2005; 39:99-104.
-
(2005)
J Pineal Res
, vol.39
, pp. 99-104
-
-
Tomas-Zapico, C.1
Coto-Montes, A.2
-
28
-
-
0033382517
-
Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative stress
-
GARCIA JJ, REITER RJ, PIE J et al. Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative stress. J Bioenerg Biomembr 1999; 31:609-616.
-
(1999)
J Bioenerg Biomembr
, vol.31
, pp. 609-616
-
-
Garcia, J.J.1
Reiter, R.J.2
Pie, J.3
-
29
-
-
0037404895
-
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical
-
TAN DX, HARDELAND R, MANCHESTER LC et al. Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical. J Pineal Res 2003; 34:249-259.
-
(2003)
J Pineal Res
, vol.34
, pp. 249-259
-
-
Tan, D.X.1
Hardeland, R.2
Manchester, L.C.3
-
30
-
-
4644244154
-
Oxidation of melatonin and its catabolites, N1-acetyl-N2-formyl-5- methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes
-
SILVA SO, RODRIGUES MR, CARVALHO SR et al. Oxidation of melatonin and its catabolites, N1-acetyl-N2-formyl-5-methoxykynuramine and N1-acetyl-5- methoxykynuramine, by activated leukocytes. J Pineal Res 2004; 37:171-175.
-
(2004)
J Pineal Res
, vol.37
, pp. 171-175
-
-
Silva, S.O.1
Rodrigues, M.R.2
Carvalho, S.R.3
-
31
-
-
14344265259
-
Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol
-
ONUKI J, ALMEIDA EA, MEDEIROS MH et al. Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol. J Pineal Res 2005; 38:107-115.
-
(2005)
J Pineal Res
, vol.38
, pp. 107-115
-
-
Onuki, J.1
Almeida, E.A.2
Medeiros, M.H.3
-
32
-
-
25144447579
-
Reaction of the melatonin metabolite AMK (N1-acrtyl-5-methoxykynuramine) with reactive nitrogen species: Formation of novel compound, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK
-
GUENTHER AL, SCHMIDT SI, LAATSCH H et al. Reaction of the melatonin metabolite AMK (N1-acrtyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compound, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK. J Pineal Res 2005; 39:251-260.
-
(2005)
J Pineal Res
, vol.39
, pp. 251-260
-
-
Guenther, A.L.1
Schmidt, S.I.2
Laatsch, H.3
-
33
-
-
0029874138
-
The NF-κB and IkB proteins: New discoveries and insights
-
BALDWIN AS, Jr. The NF-κB and IkB proteins: new discoveries and insights. Annu Rev Immunol 1996; 14:649-681.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-681
-
-
Baldwin Jr., A.S.1
-
34
-
-
19644375686
-
Molecular mechanism of TNF signaling and beyond
-
LIU ZG. Molecular mechanism of TNF signaling and beyond. Cell Res 2005; 15:24-27.
-
(2005)
Cell Res
, vol.15
, pp. 24-27
-
-
Liu, Z.G.1
-
35
-
-
5644235488
-
NF-kappaB: A multifaceted transcription factor regulated at several levels
-
SCHMITZ ML, MATTIOLI I, BUSS H et al. NF-kappaB: a multifaceted transcription factor regulated at several levels. Chembiochem 2004; 5:1348-1358.
-
(2004)
Chembiochem
, vol.5
, pp. 1348-1358
-
-
Schmitz, M.L.1
Mattioli, I.2
Buss, H.3
-
36
-
-
18844412788
-
Reactive oxygen species and the modulation of stroke
-
CRACK PJ, TAYLOR JM. Reactive oxygen species and the modulation of stroke. Free Radic Biol Med 2005; 38:1433-1444.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 1433-1444
-
-
Crack, P.J.1
Taylor, J.M.2
-
37
-
-
1842735408
-
A novel mechanism for pergolide-induced neuroprotection: Inhibition of NF-kappaB nuclear translocation
-
UBERTI D, CARSANA T, FRANCISCONI S et al. A novel mechanism for pergolide-induced neuroprotection: inhibition of NF-kappaB nuclear translocation. Biochem Pharmacol 2004; 67:1743-1750.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1743-1750
-
-
Uberti, D.1
Carsana, T.2
Francisconi, S.3
-
38
-
-
11144238299
-
Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators
-
WU KK. Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators. Prostaglandins Leukot Essent Fatty Acids 2005; 72:89-93.
-
(2005)
Prostaglandins Leukot Essent Fatty Acids
, vol.72
, pp. 89-93
-
-
Kk, W.U.1
-
39
-
-
23744455613
-
NF-kappaB and NOS may play a role in human RPMI-8402 cell apoptosis
-
TRUBIANI O, SALVOLINI E, VIGNINI A et al. NF-kappaB and NOS may play a role in human RPMI-8402 cell apoptosis. Cell Biol Int 2005; 29:529-536.
-
(2005)
Cell Biol Int
, vol.29
, pp. 529-536
-
-
Trubiani, O.1
Salvolini, E.2
Vignini, A.3
-
40
-
-
0346059342
-
Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats
-
BRUCK R, AEED H, AVNI Y et al. Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats. J Hepatol 2004; 40:86-93.
-
(2004)
J Hepatol
, vol.40
, pp. 86-93
-
-
Bruck, R.1
Aeed, H.2
Avni, Y.3
-
41
-
-
0033119372
-
Bcl-2 gene family and the regulation of programmed cell death
-
KORSMEYER SJ. Bcl-2 gene family and the regulation of programmed cell death. Cancer Res Suppl 1999; 59:1693-1700.
-
(1999)
Cancer Res Suppl
, vol.59
, pp. 1693-1700
-
-
Korsmeyer, S.J.1
-
42
-
-
18044386381
-
Melatonin attenuates amyloid beta25-35-induced apoptosis in mouse microglial BV2 cells
-
JANG MH, JUNG SB, LEE MH et al. Melatonin attenuates amyloid beta25-35-induced apoptosis in mouse microglial BV2 cells. Neurosci Lett 2005; 380:26-31.
-
(2005)
Neurosci Lett
, vol.380
, pp. 26-31
-
-
Jang, M.H.1
Jung, S.B.2
Lee, M.H.3
-
43
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
LI P, NIJHAWAN D, BUDIHARDJO I et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
44
-
-
0034727885
-
Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway
-
LOPEZ E, FERRER I. Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway. Brain Res Mol Brain Res 2000; 85:61-67.
-
(2000)
Brain Res Mol Brain Res
, vol.85
, pp. 61-67
-
-
Lopez, E.1
Ferrer, I.2
-
45
-
-
3242664824
-
Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes
-
JOU MJ, PENG TI, REITER RJ et al. Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J Pineal Res 2004; 37:55-70.
-
(2004)
J Pineal Res
, vol.37
, pp. 55-70
-
-
Jou, M.J.1
Peng, T.I.2
Reiter, R.J.3
|