Zinc-finger hydrolase: Computational selection of a linker and a sequence towards metal activation with a synthetic αββ protein

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 23, 2010, Pages 8270-8276

  Patel, Kirti ^a   Srivastava, Kinshuk Raj ^a   Durani, Susheel ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

Author keywords

interactions; Cholinesterase; Enzyme catalysis; Protein design; Protein stereochemistry; Zinc binding sites

Indexed keywords

ALANINE; ASPARTIC ACID; HISTIDINE; HYDROLASE; LEUCINE; POLYPEPTIDE; PROLINE; SERINE; TYROSINE; ZINC; ZINC FINGER PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; CIRCULAR DICHROISM; ENZYME ACTIVITY; ISOTHERMAL TITRATION CALORIMETRY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; HYDROLASES; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; ZINC; ZINC FINGERS;

EID: 78249234713     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.10.003     Document Type: Article

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