Sequence-selective and hydrolytic cleavage of DNA by zinc finger mutants

Journal of the American Chemical Society

Volumn 126, Issue 47, 2004, Pages 15374-15375

  Nomura, Akiko ^a   Sugiura, Yukio ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ZINC FINGER PROTEIN;

ARTICLE; CATALYSIS; DNA BINDING; DNA CLEAVAGE; DNA SEQUENCE; ELECTRICITY; HYDROLYSIS; MOLECULAR RECOGNITION; MUTANT; ZINC FINGER MOTIF;

EID: 7644223349     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045663l     Document Type: Article

References (38)

1. For reviews, see: (a) Long, E. C. Acc. Chem. Res. 1999, 32, 827-836. (b) Sreedhara, A.; Cowan, J. A. J. Biol. Inorg. Chem. 2001, 6, 337-347. (c) Franklin, S. J. Curr. Opin. Chem. Biol. 2001, 5, 201-208.
2. For reviews, see: (a) Long, E. C. Acc. Chem. Res. 1999, 32, 827-836. (b) Sreedhara, A.; Cowan, J. A. J. Biol. Inorg. Chem. 2001, 6, 337-347. (c) Franklin, S. J. Curr. Opin. Chem. Biol. 2001, 5, 201-208.
3. For reviews, see: (a) Long, E. C. Acc. Chem. Res. 1999, 32, 827-836. (b) Sreedhara, A.; Cowan, J. A. J. Biol. Inorg. Chem. 2001, 6, 337-347. (c) Franklin, S. J. Curr. Opin. Chem. Biol. 2001, 5, 201-208.
4. For recent examples, see: (a) Sissi, C.; Rossi, P.; Felluga, F.; Formaggio, F.; Palumbo, M.; Tecilla, P.; Tonioli, C.; Scrimin, P. J. Am. Chem. Soc. 2001, 123, 3169-3170. (b) Bibikova, M.; Carroll, D.; Segal, D. J.; Trautman, J. K.; Smith, J.; Kim, Y. G.; Chandrasegaran, S. Mol. Cell. Biol. 2001, 21, 289-297. (c) Copeland, K. D.; Fitzsimons, M. P.; Houser, R. P.; Barton, J. K. Biochemistry 2002, 41, 343-356. (d) Boseggia, E.; Gatos, M.; Lucatello, L.; Mancin, F.; Moro, S.; Palumbo, M.; Sissi, C.; Tecilla, P.; Tonellato, U.; Zagotto, G. J. Am. Chem. Soc. 2004, 126, 4543-4549.
5. For recent examples, see: (a) Sissi, C.; Rossi, P.; Felluga, F.; Formaggio, F.; Palumbo, M.; Tecilla, P.; Tonioli, C.; Scrimin, P. J. Am. Chem. Soc. 2001, 123, 3169-3170. (b) Bibikova, M.; Carroll, D.; Segal, D. J.; Trautman, J. K.; Smith, J.; Kim, Y. G.; Chandrasegaran, S. Mol. Cell. Biol. 2001, 21, 289-297. (c) Copeland, K. D.; Fitzsimons, M. P.; Houser, R. P.; Barton, J. K. Biochemistry 2002, 41, 343-356. (d) Boseggia, E.; Gatos, M.; Lucatello, L.; Mancin, F.; Moro, S.; Palumbo, M.; Sissi, C.; Tecilla, P.; Tonellato, U.; Zagotto, G. J. Am. Chem. Soc. 2004, 126, 4543-4549.
6. For recent examples, see: (a) Sissi, C.; Rossi, P.; Felluga, F.; Formaggio, F.; Palumbo, M.; Tecilla, P.; Tonioli, C.; Scrimin, P. J. Am. Chem. Soc. 2001, 123, 3169-3170. (b) Bibikova, M.; Carroll, D.; Segal, D. J.; Trautman, J. K.; Smith, J.; Kim, Y. G.; Chandrasegaran, S. Mol. Cell. Biol. 2001, 21, 289-297. (c) Copeland, K. D.; Fitzsimons, M. P.; Houser, R. P.; Barton, J. K. Biochemistry 2002, 41, 343-356. (d) Boseggia, E.; Gatos, M.; Lucatello, L.; Mancin, F.; Moro, S.; Palumbo, M.; Sissi, C.; Tecilla, P.; Tonellato, U.; Zagotto, G. J. Am. Chem. Soc. 2004, 126, 4543-4549.
7. For recent examples, see: (a) Sissi, C.; Rossi, P.; Felluga, F.; Formaggio, F.; Palumbo, M.; Tecilla, P.; Tonioli, C.; Scrimin, P. J. Am. Chem. Soc. 2001, 123, 3169-3170. (b) Bibikova, M.; Carroll, D.; Segal, D. J.; Trautman, J. K.; Smith, J.; Kim, Y. G.; Chandrasegaran, S. Mol. Cell. Biol. 2001, 21, 289-297. (c) Copeland, K. D.; Fitzsimons, M. P.; Houser, R. P.; Barton, J. K. Biochemistry 2002, 41, 343-356. (d) Boseggia, E.; Gatos, M.; Lucatello, L.; Mancin, F.; Moro, S.; Palumbo, M.; Sissi, C.; Tecilla, P.; Tonellato, U.; Zagotto, G. J. Am. Chem. Soc. 2004, 126, 4543-4549.
8. (a) Huang, X.; Pieczko, M. E.; Long, E. C. Biochemistry 1999, 38, 2160-2166.
9. (b) Ananias, D. C.; Long, E. C. Inorg. Chem. 1997, 36, 2469-2471.
10. (a) Mack, D. P.; Iverson, B. L.; Dervan, P. B. J. Am. Chem. Soc. 1988, 110, 7572-7574.
11. (b) Nagaoka, M.; Hagihara, M.; Kuwahara, J.; Sugiura, Y. J. Am. Chem. Soc. 1994, 116, 4085-4086.
12. (c) Harford, C.; Narindrasorasak, S.; Sarkar, B. Biochemistry 1996, 35, 4271-4278.
13. (a) Welch, J. T.; Sirish, M.; Lindstrom, K. M.; Franklin, S. J. Inorg. Chem. 2001, 40, 1982-1984.
14. (b) Kovacic, R. T.; Welch, J. T.; Franklin, S. J. J. Am. Chem. Soc. 2003, 125, 6656-6662.
15. Nomura, A.; Sugiura, Y. Inorg. Chem. 2004, 43, 1708-1713.
16. (a) Laity, J. H.; Lee, B. M.; Wright, P. E. Curr. Opin. Struct. Biol. 2001, 11, 39-46.
17. (b) Wolfe, S. A.; Nekludova, L.; Pabo, C. O. Annu. Rev. Biophys. Biomol. Struct. 2000, 29, 183-212.
18. Kamiuchi, T.; Abe, E.; Imanishi, M.; Kaji, T.; Nagaoka, M.; Sugiura, Y. Biochemistry 1998, 37, 13827-13834.
19. Nagaoka, M.; Doi, Y.; Kuwahara, J.; Sugiura, Y. J. Am. Chem. Soc. 2002, 124, 6526-6527.
20. (a) Segal, D. J.; Beerli, R. R.; Blancafort, P.; Dreier, B.; Effertz, K.; Huber, A.; Koksch, B.; Lund, C. V.; Magnenat, L.; Valente, D.; Barbas, C. F., III. Biochemistry 2003, 42, 2137-2148.
21. (b) Beerli, R. R.; Barbas, C. F., III. Nat. Biotechnol. 2002, 20, 135-141.
22. (c) Segal, D. J.; Barbas, C. F., III. Curr. Opin. Biotechnol. 2001, 12, 632-637.
23. (d) Sera, T.; Uranga, C. Biochemistry 2002, 41, 7074-7081.
24. (a) Koike, f.; Kimura, E. J. Am. Chem. Soc. 1991, 113, 8935-8941.
25. (b) Kimura, E.; Kodama, Y.; Koike, T.; Shiro, M. J. Am. Chem. Soc. 1995, 117, 8304-8311.
26. (c) Hettich, R.; Schneider, H.-J. J. Am. Chem. Soc. 1997, 119, 5638-5647.
27. (d) Deck, K. M.; Tseng, T. A.; Burstyn, J. N. Inorg. Chem. 2002, 41, 669-677.
28. 18 therefore, only the degradation of BNP proceeded under our experimental conditions (ref 11a).
29. (a) Koike, T.; Takamura, M.; Kimura, E. J. Am. Chem. Soc. 1994, 116, 8443-8449.
30. (b) Kimura, E. Acc. Chem. Res. 2001, 34, 171-179.
31. (c) Jang. B.-B.; Lee, K. P.; Min, D. H.; Suh, J. J. Am. Chem. Soc. 1998, 120, 12008-12016.
32. (a) Kadonaga, J. T.; Jones, K. A.; Tjian, R. Trends Biochem, Sci. 1986, 11, 20-23.
33. (b) Kriwacki, R. W.; Schultz, S. C.; Steitz, T. A.; Caradonna, J. P. Proc. Natl. Acad. Sci. U.S.A. 1992, 89, 9759-9763.
34. (c) Kuwahara, J.; Yonezawa, A.; Futamura, M.; Sugiura, Y. Biochemistry 1993, 32, 5994-6001.
35. The present DNA cleavage did not change in anaerobic conditions, indicating that the possibility of a metal ion-driven oxidative cleavage process can be ruled out.
36. Yokono, M.; Saegusa, N.; Matsushita, K.; Sugiura, Y. Biochemistry 1998, 37, 6824-6832.
37. Hori, Y.; Suzuki, K.; Okuno, Y.; Nagaoka, M.; Futaki, S.; Sugiura, Y. J. Am. Chem. Soc. 2000, 122, 7648-7653.
38. Kirby, A. J.; Jencks, W. P. J. Am. Chem. Soc. 1965, 87, 3209-3216.