Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility

Biochemistry

Volumn 49, Issue 45, 2010, Pages 9739-9745

  Mosbæk, Charlotte Rode ^a   Nolan, David ^b   Persson, Egon ^b   Svergun, Dmitri I ^c   Bukrinsky, Jens Thostrup ^b   Vestergaard, Bente ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BLOOD COAGULATION; COMPLEX FORMATIONS; EXPERIMENTAL CONDITIONS; INTER-DOMAIN; PHARMACEUTICAL PRODUCTS; SMALL ANGLE X-RAY SCATTERING; SMALL-ANGLE SCATTERING; SOLUTION BEHAVIOR; STRUCTURAL REARRANGEMENT; TISSUE FACTORS;

BLOOD; COAGULATION; CONFORMATIONS; ISOMERS; OLIGOMERS; X RAY SCATTERING;

SCATTERING;

BLOOD CLOTTING FACTOR 7A; DIMER; THROMBOPLASTIN;

ARTICLE; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

CRYSTALLIZATION; FACTOR VIIA; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SECRETORY VESICLES; THROMBOPLASTIN; X-RAY DIFFRACTION;

EID: 78149463930     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1011207     Document Type: Article

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