메뉴 건너뛰기




Volumn 9, Issue 3, 1998, Pages 195-204

Analysis of the site-specific asparagine-linked glycosylation of recombinant human coagulation factor VIIa by glycosidase digestions, liquid chromatography, and mass spectrometry

Author keywords

Carbohydrate characterization; Coagulation factor VII; Exoglycosidases; Liquid chromatography; MALDI MS

Indexed keywords

ASPARAGINE LINKED OLIGOSACCHARIDE; CARBOHYDRATE; GALACTOSE; GLYCOSIDASE; N ACETYLGALACTOSAMINE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SIALIC ACID;

EID: 0031655586     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02915793     Document Type: Article
Times cited : (30)

References (32)
  • 1
    • 0023784390 scopus 로고
    • Amino acid sequence and posttranslational modifications of human factor Vila from plasma and transfected baby hamster kidney cells
    • Thim, L., Bjoern, S., Christensen, M., Nicolaisen, E. M., Lund-Hansen, T., Pedersen, A. H., and Hedner, U. (1988) Amino acid sequence and posttranslational modifications of human factor Vila from plasma and transfected baby hamster kidney cells. Biochemistry 27, 7785-7793.
    • (1988) Biochemistry , vol.27 , pp. 7785-7793
    • Thim, L.1    Bjoern, S.2    Christensen, M.3    Nicolaisen, E.M.4    Lund-Hansen, T.5    Pedersen, A.H.6    Hedner, U.7
  • 2
    • 0025764566 scopus 로고
    • Human plasma and recombinant factor VII. Characterization of O-glycosylations at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine
    • Bjoern, S., Foster, D.C., Thim, L., Wiberg, F., Christensen, M., Komiyama, Y., Pedersen, A. H., and Kisiel, W. (1991) Human plasma and recombinant factor VII. Characterization of O-glycosylations at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine. J. Biol. Chem. 266, 11051-11057.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11051-11057
    • Bjoern, S.1    Foster, D.C.2    Thim, L.3    Wiberg, F.4    Christensen, M.5    Komiyama, Y.6    Pedersen, A.H.7    Kisiel, W.8
  • 3
    • 0028889070 scopus 로고
    • Characterization of glycopeptides from recombinant coagulation factor Vila by high-performance liquid chromatography and capillary zone electrophoresis using ultraviolet and pulsed electrochemical detection
    • Weber, P. L., Kornfelt, T., Klausen, N. K., and Lunte, S. M. (1995) Characterization of glycopeptides from recombinant coagulation factor Vila by high-performance liquid chromatography and capillary zone electrophoresis using ultraviolet and pulsed electrochemical detection. Anal. Biochem. 225, 135-142.
    • (1995) Anal. Biochem. , vol.225 , pp. 135-142
    • Weber, P.L.1    Kornfelt, T.2    Klausen, N.K.3    Lunte, S.M.4
  • 4
    • 0028839675 scopus 로고
    • Analysis of the glycoforms of human recombinant factor Vila by capillary electrophoresis and high-performance liquid chromatography
    • Klausen, N. K. and Kornfelt, T. (1995) Analysis of the glycoforms of human recombinant factor Vila by capillary electrophoresis and high-performance liquid chromatography. J. Chromatogr. 718, 195-202.
    • (1995) J. Chromatogr. , vol.718 , pp. 195-202
    • Klausen, N.K.1    Kornfelt, T.2
  • 5
    • 0026793042 scopus 로고
    • The asparagine-linked oligosaccharides at individual glycosylation sites in human thyrotrophin
    • Hiyama, J., Weisshaar, G., and Renwick, A. G. C. (1992) The asparagine-linked oligosaccharides at individual glycosylation sites in human thyrotrophin. Glycobiology 2, 401-409.
    • (1992) Glycobiology , vol.2 , pp. 401-409
    • Hiyama, J.1    Weisshaar, G.2    Renwick, A.G.C.3
  • 6
    • 0028957067 scopus 로고
    • Structural analysis of the sialylated N- and O-linked carbohydrate chains of recombinant human erythropoitin expressed in chinese hamster ovary cells. Sialylation patterns and branch location of dimeric N-acetyllactosamine units
    • Hokke, C. H., Bergwerff, A. A., Van Dedem, G. W. K., Kamerling, J. P., and Vliegenthart, J. F. G. (1995) Structural analysis of the sialylated N-and O-linked carbohydrate chains of recombinant human erythropoitin expressed in chinese hamster ovary cells. Sialylation patterns and branch location of dimeric N-acetyllactosamine units. Eur. J. Biochem. 228, 981-1008.
    • (1995) Eur. J. Biochem. , vol.228 , pp. 981-1008
    • Hokke, C.H.1    Bergwerff, A.A.2    Van Dedem, G.W.K.3    Kamerling, J.P.4    Vliegenthart, J.F.G.5
  • 8
    • 0026908629 scopus 로고
    • High-performance anion-exchange chromatography coupled with mass spectrometry for the determination of carbohydrates
    • Conboy, J. J. and Henion, J. D. (1992) High-performance anion-exchange chromatography coupled with mass spectrometry for the determination of carbohydrates. Biol. Mass Spectrom. 21, 397-407.
    • (1992) Biol. Mass Spectrom. , vol.21 , pp. 397-407
    • Conboy, J.J.1    Henion, J.D.2
  • 9
    • 0030014292 scopus 로고    scopus 로고
    • Rapid monitoring of site-specific glycosylation microheterogeneity of recombinant human interferon-γ
    • Harmon, B. J., Gu, X., and Wang, D. I. C. (1996) Rapid monitoring of site-specific glycosylation microheterogeneity of recombinant human interferon-γ. Anal. Chem. 68, 1465-1473.
    • (1996) Anal. Chem. , vol.68 , pp. 1465-1473
    • Harmon, B.J.1    Gu, X.2    Wang, D.I.C.3
  • 10
    • 0025677742 scopus 로고
    • Linkage analysis using Lindberg method
    • (McCloskey, J. A., ed.), Academic Press, San Diego
    • Hellerqvist, C. G. (1990) Linkage analysis using Lindberg method, in Methods in Enzymology, vol. 193 (McCloskey, J. A., ed.), Academic Press, San Diego, pp. 554-573.
    • (1990) Methods in Enzymology , vol.193 , pp. 554-573
    • Hellerqvist, C.G.1
  • 12
    • 0028787776 scopus 로고
    • An integrated strategy for structural characterization of the protein and carbohydrate components of monoclonal antibodies: Application to anti-respiratory syncytial virus MAb
    • Roberts, G. D., Johnson, W. P., Burman, S., Anumula, K. R., and Carr, S. A. (1995) An integrated strategy for structural characterization of the protein and carbohydrate components of monoclonal antibodies: Application to anti-respiratory syncytial virus MAb. Anal. Chem. 67, 3613-3625.
    • (1995) Anal. Chem. , vol.67 , pp. 3613-3625
    • Roberts, G.D.1    Johnson, W.P.2    Burman, S.3    Anumula, K.R.4    Carr, S.A.5
  • 14
    • 0028349781 scopus 로고
    • Site-specific characterization of glycoprotein carbohydrates by exoglycosidase digestion and laser desorption mass spectrometry
    • Sutton, C. W., O'Neill, J. A., and Cottrell, J. S. (1994) Site-specific characterization of glycoprotein carbohydrates by exoglycosidase digestion and laser desorption mass spectrometry. Anal. Biochem. 218, 34-46.
    • (1994) Anal. Biochem. , vol.218 , pp. 34-46
    • Sutton, C.W.1    O'Neill, J.A.2    Cottrell, J.S.3
  • 15
    • 84989028063 scopus 로고
    • Examination of complex oligosaccharides by matrix-assisted laser desorption/ionization mass spectrometry on time-of-flight and magnetic sector instruments
    • Harvey, D. J., Rudd, P. M., Bateman, R. H., Bordoli, R. S., Howes, K., Hoyes, J. B., and Vickers, R. G. (1994) Examination of complex oligosaccharides by matrix-assisted laser desorption/ionization mass spectrometry on time-of-flight and magnetic sector instruments. Organic Mass Spectrometry 29, 753-765.
    • (1994) Organic Mass Spectrometry , vol.29 , pp. 753-765
    • Harvey, D.J.1    Rudd, P.M.2    Bateman, R.H.3    Bordoli, R.S.4    Howes, K.5    Hoyes, J.B.6    Vickers, R.G.7
  • 16
    • 12044253267 scopus 로고
    • From ions in solution to ions in the gas phase - the mechanism of electrospray mass spectrometry
    • Kebarle, P. and Tang, L. (1993) From ions in solution to ions in the gas phase - the mechanism of electrospray mass spectrometry. Anal. Chem. 65, 972A-986A.
    • (1993) Anal. Chem. , vol.65
    • Kebarle, P.1    Tang, L.2
  • 17
    • 0001061864 scopus 로고
    • Analysis of neutral oligosaccharides by matrix-assisted laser desorption/ionisation mass spectrometry
    • Stahl, B., Steup, M., Karas, M., and Hillenkamp, F. (1991) Analysis of neutral oligosaccharides by matrix-assisted laser desorption/ionisation mass spectrometry. Anal. Chem. 63, 1463-1466.
    • (1991) Anal. Chem. , vol.63 , pp. 1463-1466
    • Stahl, B.1    Steup, M.2    Karas, M.3    Hillenkamp, F.4
  • 18
    • 0027318961 scopus 로고
    • Biological roles of oligosaccharides: All of the theories are correct
    • Varki, A. (1993) Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 3 97-130.
    • (1993) Glycobiology , vol.3 , pp. 97-130
    • Varki, A.1
  • 19
    • 0027944498 scopus 로고
    • The major form of the murine asialoglycoprotein receptor: CDNA sequence and expression in liver, testis and epididymis
    • Monroe, R. S. and Huber, B. E. (1994) The major form of the murine asialoglycoprotein receptor: cDNA sequence and expression in liver, testis and epididymis. Gene 148 237-244.
    • (1994) Gene , vol.148 , pp. 237-244
    • Monroe, R.S.1    Huber, B.E.2
  • 21
    • 0027441378 scopus 로고
    • Use of hydrazine to release in intact and unreduced form both N-and O-linked oligosaccharides form glycoproteins
    • Patel, T., Bruce, J., Merry, A., Bigge, C., Wormald, M., Jaques, A., and Parekh, R. (1993) Use of hydrazine to release in intact and unreduced form both N-and O-linked oligosaccharides form glycoproteins. Biochem. 32, 679-693.
    • (1993) Biochem. , vol.32 , pp. 679-693
    • Patel, T.1    Bruce, J.2    Merry, A.3    Bigge, C.4    Wormald, M.5    Jaques, A.6    Parekh, R.7
  • 22
    • 0029164230 scopus 로고
    • Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid
    • Bigge, J. C., Patel, T. P., Bruce, J. A., Goulding, P. N., Charles, S. M., and Parekh, R. B. (1995) Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. Anal. Biochem. 230, 229-238.
    • (1995) Anal. Biochem. , vol.230 , pp. 229-238
    • Bigge, J.C.1    Patel, T.P.2    Bruce, J.A.3    Goulding, P.N.4    Charles, S.M.5    Parekh, R.B.6
  • 23
    • 0342976375 scopus 로고
    • Separation of positional isomers of oligosaccharides and glycopeptides by high-performance union-exchange chromatography with pulsed amperometric detection
    • Hardy, M. R. and Townsend, R. R. (1988) Separation of positional isomers of oligosaccharides and glycopeptides by high-performance union-exchange chromatography with pulsed amperometric detection. Proc. Natl. Acad. Sci. USA 85 3289-3293.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 3289-3293
    • Hardy, M.R.1    Townsend, R.R.2
  • 24
    • 0030030482 scopus 로고    scopus 로고
    • Oligosaccharide sequencing based on exo- And endoglycosidase digestion and liquid chromatographic analysis of the products
    • Prime, S., Dearnley, J., Ventom, A. M., Parekh, R. B., and Edge, C. J. (1996) Oligosaccharide sequencing based on exo-and endoglycosidase digestion and liquid chromatographic analysis of the products. J. Chrom. A 720, 263-274.
    • (1996) J. Chrom. A , vol.720 , pp. 263-274
    • Prime, S.1    Dearnley, J.2    Ventom, A.M.3    Parekh, R.B.4    Edge, C.J.5
  • 25
    • 0029175060 scopus 로고
    • Matrix assisted laser desorption ionisation mass spectrometry - improved matrix for oligosaccharides
    • Mohr, M. D., Bornsen, K. O., and Widmer, H. M. (1995) Matrix assisted laser desorption ionisation mass spectrometry - improved matrix for oligosaccharides. Rapid Comm. Mass Spectrometry 9, 809-814.
    • (1995) Rapid Comm. Mass Spectrometry , vol.9 , pp. 809-814
    • Mohr, M.D.1    Bornsen, K.O.2    Widmer, H.M.3
  • 26
    • 0028869433 scopus 로고
    • A cluster of basic amino acids within an α-helix is essential for α-subunit recognition by the glycohormone N-acetylgalactosaminyltransferase
    • Mengeling, B. J., Manzella, S. M., and Baenziger, J. U. (1995) A cluster of basic amino acids within an α-helix is essential for α-subunit recognition by the glycohormone N-acetylgalactosaminyltransferase. Proc. Natl. Acad. Sci. USA 92, 502-506.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 502-506
    • Mengeling, B.J.1    Manzella, S.M.2    Baenziger, J.U.3
  • 28
    • 0030937062 scopus 로고    scopus 로고
    • Glycosylation: Heterogeneity and the 3D structure of proteins
    • Rudd, P. M. and Dwek, R. A. (1997) Glycosylation: Heterogeneity and the 3D structure of proteins. Crit. Rev. Biochem. Mol. Biol. 32, 1-100.
    • (1997) Crit. Rev. Biochem. Mol. Biol. , vol.32 , pp. 1-100
    • Rudd, P.M.1    Dwek, R.A.2
  • 30
    • 0029841498 scopus 로고    scopus 로고
    • Differential ligand binding by two subunits of the rat liver asialoglycoprotein receptor
    • Ruiz, N. I. and Drickamer, K. (1996) Differential ligand binding by two subunits of the rat liver asialoglycoprotein receptor. Glycobiology 6, 551-559.
    • (1996) Glycobiology , vol.6 , pp. 551-559
    • Ruiz, N.I.1    Drickamer, K.2
  • 31
    • 0029935180 scopus 로고    scopus 로고
    • Selective sugar binding to the carbohydrate recognition domains of the rat hepatic and macrophage asialoglycoprotein receptors
    • Iobst, S. T. and Drickamer, K. (1996) Selective sugar binding to the carbohydrate recognition domains of the rat hepatic and macrophage asialoglycoprotein receptors. J. Biol. Chem. 271, 6686-6693.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6686-6693
    • Iobst, S.T.1    Drickamer, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.