Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice

Toxicological Sciences

Volumn 50, Issue 1, 1999, Pages 82-89

  Peters, J M ^a   Morishima, H ^a   Ward, J M ^a   Coakley, C J ^a   Kimura, S ^a   Gonzalez, F J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Carcinogenicity; CYP1A2; Cytochrome P 450 (CYP); Phenacetin; Toxicity

Indexed keywords

PARACETAMOL; PHENACETIN; PHENACETIN O DEETHYLASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CARCINOGENICITY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME METABOLISM; HEPATOMEGALY; HISTOPATHOLOGY; KIDNEY CARCINOMA; MALE; MOUSE; NONHUMAN; ORGAN WEIGHT; SPLENOMEGALY;

ACETAMINOPHEN; ANIMALS; CARCINOGENS; CARCINOMA; CYTOCHROME P-450 CYP1A2; FEMALE; KIDNEY NEOPLASMS; MALE; MICE; ORGAN SIZE; PHENACETIN; SURVIVAL RATE; TIME FACTORS; URINARY BLADDER;

ANIMALIA;

EID: 0032789454     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/50.1.82     Document Type: Article

References (19)

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