Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes

Drug Metabolism and Disposition

Volumn 37, Issue 6, 2009, Pages 1305-1311

  Mathijs, Karen ^a   Kienhuis, Anne S ^a   Brauers, Karen J J ^a   Jennen, Danyel G J ^a   Lahoz, Agustin ^b   Kleinjans, Jos C S ^a   Van Delft, Joost H M ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4' HYDROXYMEPHENYTOIN; 6 HYDROXYCHLORZOXAZONE; ACYLTRANSFERASE; ALPHA HYDROXYMIDAZOLAM; AMFEBUTAMONE; BUFURALOL; CHLORZOXAZONE; COLLAGEN; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2B9; CYTOCHROME P450 2E1; CYTOCHROME P450 3A11; CYTOCHROME P450 3A4; DICLOFENAC; DRUG METABOLITE; EPOXIDE HYDROLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MEPHENYTOIN; MIDAZOLAM; PARACETAMOL; PHENACETIN; RADAFAXINE; SULFOTRANSFERASE; UMBELLIFERONE; UNINDEXED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION PROFILING; LIVER CELL CULTURE; MALE; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOBIOTIC METABOLISM;

ANIMALS; BIOTRANSFORMATION; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CULTURE MEDIA; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION PROFILING; HEPATOCYTES; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER;

MUS MUSCULUS; RATTUS;

EID: 66649084074     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.025775     Document Type: Article

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