L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments

Journal of Neuroscience Research

Volumn 88, Issue 14, 2010, Pages 3111-3124

  Ramsey, Chenere P ^a   Giasson, Benoit I ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Dimerization; DJ 1; Mutation; Parkinson disease; Proteasome; Solubility; Stability

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DJ 1 PROTEIN; DNA; HOMODIMER; PROTEASOME; PROTEASOME INHIBITOR;

ANIMAL CELL; ARTICLE; DIMERIZATION; FEMALE; GEL PERMEATION CHROMATOGRAPHY; GENE MUTATION; HUMAN; MISSENSE MUTATION; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN VARIANT; WILD TYPE;

ANIMALS; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; INCLUSION BODIES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; ONCOGENE PROTEINS; PARKINSON DISEASE; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; SOLUBILITY;

EID: 78149355999     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22477     Document Type: Article

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