Effects of solute miscibility on the micro- and macroscopic structural integrity of freeze-dried solids

Journal of Pharmaceutical Sciences

Volumn 99, Issue 11, 2010, Pages 4710-4719

  Izutsu, K ^a   Fujii, K ^b   Katori, C ^b   Yomota, C ^a   Kawanishi, T ^a   Yoshihashi, Y ^b   Yonemochi, E ^b   Terada, K ^b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

Amorphous; Calorimetry (DSC); Formulation; Freeze drying lyophilization; Glass transition; Thermal analysis

Indexed keywords

DEXTRAN; POLYMER; POVIDONE;

ARTICLE; CHEMICAL STRUCTURE; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; MICROSCOPY; MISCIBILITY; PHASE TRANSITION; SCANNING ELECTRON MICROSCOPY; SOLID; SOLUTE; THERMAL ANALYSIS;

EID: 78149338327     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22170     Document Type: Article

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