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Volumn 30, Issue 11, 2010, Pages 809-816

Inhibition of the phosphatidylinositol-3-kinase pathway abrogates polyinosinic:polycytidylic acid-stimulated hyaluronan-mediated human mucosal smooth muscle cell binding of U937 monocytic cells

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYALURONIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE B;

EID: 78149322286     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2009.0061     Document Type: Article
Times cited : (7)

References (37)
  • 1
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NFkappaB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NFkappaB by Toll-like receptor 3. Nature 413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 2
    • 26444448463 scopus 로고    scopus 로고
    • The survival kinases Akt and Pim as potential pharmacological targets
    • Amaravadi R, Thompson CB. 2005. The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest 115:2618-2624.
    • (2005) J Clin Invest , vol.115 , pp. 2618-2624
    • Amaravadi, R.1    Thompson, C.B.2
  • 3
    • 55349134911 scopus 로고    scopus 로고
    • Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1
    • Bandyopadhyay SK, de la Motte CA, Kessler SP, Hascall VC, Hill DR, Strong SA. 2008. Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1. Am J Pathol 173:1361-1368.
    • (2008) Am J Pathol , vol.173 , pp. 1361-1368
    • Bandyopadhyay, S.K.1    De La Motte, C.A.2    Kessler, S.P.3    Hascall, V.C.4    Hill, D.R.5    Strong, S.A.6
  • 4
    • 0034651653 scopus 로고    scopus 로고
    • Induction of E-selectin expression by double-stranded RNA and TNF-alpha is attenuated in murine aortic endothelial cells derived from double-stranded RNA-activated kinase (PKR)- null mice
    • Bandyopadhyay SK, de la Motte CA, Williams BR. 2000. Induction of E-selectin expression by double-stranded RNA and TNF-alpha is attenuated in murine aortic endothelial cells derived from double-stranded RNA-activated kinase (PKR)- null mice. J Immunol 164:2077-2083.
    • (2000) J Immunol , vol.164 , pp. 2077-2083
    • Bandyopadhyay, S.K.1    De La Motte, C.A.2    Williams, B.R.3
  • 6
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. 2002. The phosphoinositide 3-kinase pathway. Science 296:1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 7
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr., Kerr IM, Stark GR. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 8
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: a play in three Akts. Genes Dev 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 9
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T, Kovarik P. 2000. Serine phosphorylation of STATs. Oncogene 19:2628-2637.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 10
    • 0032698135 scopus 로고    scopus 로고
    • Mononuclear leukocytes preferentially bind via CD44 to hyaluronan on human intestinal mucosal smooth muscle cells after virus infection or treatment with poly(I.C)
    • de la Motte CA, Hascall VC, Calabro A, Yen-Lieberman B, Strong SA. 1999. Mononuclear leukocytes preferentially bind via CD44 to hyaluronan on human intestinal mucosal smooth muscle cells after virus infection or treatment with poly(I.C). J Biol Chem 274:30747-30755.
    • (1999) J Biol Chem , vol.274 , pp. 30747-30755
    • De La Motte, C.A.1    Hascall, V.C.2    Calabro, A.3    Yen-Lieberman, B.4    Strong, S.A.5
  • 11
    • 0037969876 scopus 로고    scopus 로고
    • Mononuclear leukocytes bind to specific hyaluronan structures on colon mucosal smooth muscle cells treated with polyinosinic acid:polycytidylic acid: Interalpha- trypsin inhibitor is crucial to structure and function
    • de la Motte CA, Hascall VC, Drazba J, Bandyopadhyay SK, Strong SA. 2003. Mononuclear leukocytes bind to specific hyaluronan structures on colon mucosal smooth muscle cells treated with polyinosinic acid:polycytidylic acid: interalpha- trypsin inhibitor is crucial to structure and function. Am J Pathol 163:121-133.
    • (2003) Am J Pathol , vol.163 , pp. 121-133
    • De La Motte, C.A.1    Hascall, V.C.2    Drazba, J.3    Bandyopadhyay, S.K.4    Strong, S.A.5
  • 12
    • 1342321750 scopus 로고    scopus 로고
    • PI 3-kinase, Akt and cell survival
    • Downward J. 2004. PI 3-kinase, Akt and cell survival. Semin Cell Dev Biol 15:177-182.
    • (2004) Semin Cell Dev Biol , vol.15 , pp. 177-182
    • Downward, J.1
  • 14
    • 33644907733 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis
    • Feinberg MW, Jain MK. 2005. Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis. Panminerva Med 47:169-186.
    • (2005) Panminerva Med , vol.47 , pp. 169-186
    • Feinberg, M.W.1    Jain, M.K.2
  • 16
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC. 1997. PI3K: downstream AKTion blocks apoptosis. Cell 88:435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 18
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • Hu P, Han Z, Couvillon AD, Exton JH. 2004. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem 279:49420-49429.
    • (2004) J Biol Chem , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 19
    • 65749101996 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease
    • Kaser A, Blumberg RS. 2009. Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease. Semin Immunol. 21:156-163.
    • (2009) Semin Immunol. , vol.21 , pp. 156-163
    • Kaser, A.1    Blumberg, R.S.2
  • 22
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like receptor and RIG-I-like receptor signaling
    • Kawai T, Akira S. 2008. Toll-like receptor and RIG-I-like receptor signaling. Ann N Y Acad Sci 1143:1-20.
    • (2008) Ann N y Acad Sci , vol.1143 , pp. 1-20
    • Kawai, T.1    Akira, S.2
  • 23
    • 0033598839 scopus 로고    scopus 로고
    • Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
    • Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T. 1999. Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proc Natl Acad Sci U S A 96:13956-13961.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 13956-13961
    • Kovarik, P.1    Stoiber, D.2    Eyers, P.A.3    Menghini, R.4    Neininger, A.5    Gaestel, M.6    Cohen, P.7    Decker, T.8
  • 24
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin WW, Karin M. 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117:1175-1183.
    • (2007) J Clin Invest , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 26
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E, Tschopp J, Karin M. 2006. Intracellular pattern recognition receptors in the host response. Nature 442:39-44.
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 27
    • 0035823494 scopus 로고    scopus 로고
    • Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression
    • Nguyen H, Ramana CV, Bayes J, Stark GR. 2001. Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. J Biol Chem 276:33361-33368.
    • (2001) J Biol Chem , vol.276 , pp. 33361-33368
    • Nguyen, H.1    Ramana, C.V.2    Bayes, J.3    Stark, G.R.4
  • 29
    • 23744483354 scopus 로고    scopus 로고
    • TLR3 in antiviral immunity: Key player or bystander?
    • Schroder M, Bowie AG. 2005. TLR3 in antiviral immunity: key player or bystander? Trends Immunol 26:462-468.
    • (2005) Trends Immunol , vol.26 , pp. 462-468
    • Schroder, M.1    Bowie, A.G.2
  • 30
    • 14044260466 scopus 로고    scopus 로고
    • Transcriptional signaling by doublestranded RNA: Role of TLR3
    • Sen GC, Sarkar SN. 2005. Transcriptional signaling by doublestranded RNA: role of TLR3. Cytokine Growth Factor Rev 16:1-14.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 1-14
    • Sen, G.C.1    Sarkar, S.N.2
  • 31
    • 0037188941 scopus 로고    scopus 로고
    • Role of Akt signaling in vascular homeostasis and angiogenesis
    • DOI 10.1161/01.RES.0000022200.71892.9F
    • Shiojima I, Walsh K. 2002. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ Res 90:1243-1250. (Pubitemid 34787405)
    • (2002) Circulation Research , vol.90 , Issue.12 , pp. 1243-1250
    • Shiojima, I.1    Walsh, K.2
  • 33
    • 0035958846 scopus 로고    scopus 로고
    • Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701
    • Stephanou A, Scarabelli TM, Brar BK, Nakanishi Y, Matsumura M, Knight RA, Latchman DS. 2001. Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701. J Biol Chem 276:28340-28347.
    • (2001) J Biol Chem , vol.276 , pp. 28340-28347
    • Stephanou, A.1    Scarabelli, T.M.2    Brar, B.K.3    Nakanishi, Y.4    Matsumura, M.5    Knight, R.A.6    Latchman, D.S.7
  • 34
    • 39149107423 scopus 로고    scopus 로고
    • MDA5/RIG-I and virus recognition
    • Takeuchi O, Akira S. 2008. MDA5/RIG-I and virus recognition. Curr Opin Immunol 20:17-22.
    • (2008) Curr Opin Immunol , vol.20 , pp. 17-22
    • Takeuchi, O.1    Akira, S.2
  • 35
    • 85047690934 scopus 로고    scopus 로고
    • Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
    • Tessner TG, Muhale F, Riehl TE, Anant S, Stenson WF. 2004. Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation. J Clin Invest 114:1676-1685.
    • (2004) J Clin Invest , vol.114 , pp. 1676-1685
    • Tessner, T.G.1    Muhale, F.2    Riehl, T.E.3    Anant, S.4    Stenson, W.F.5
  • 36
    • 17144386566 scopus 로고    scopus 로고
    • Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells. only phosphatidylinositol 30-kinase is important
    • Vantler M, Caglayan E, Zimmermann WH, Baumer AT, Rosenkranz S. 2005. Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells. Only phosphatidylinositol 30-kinase is important. J Biol Chem 280: 14168-14176.
    • (2005) J Biol Chem , vol.280 , pp. 14168-14176
    • Vantler, M.1    Caglayan, E.2    Zimmermann, W.H.3    Baumer, A.T.4    Rosenkranz, S.5
  • 37
    • 33751183307 scopus 로고    scopus 로고
    • Toll-like receptor 3 signaling evokes a proinflammatory and proliferative phenotype in human vascular smooth muscle cells
    • Yang X, Murthy V, Schultz K, Tatro JB, Fitzgerald KA, Beasley D. 2006. Toll-like receptor 3 signaling evokes a proinflammatory and proliferative phenotype in human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 291: H2334-H2343.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Yang, X.1    Murthy, V.2    Schultz, K.3    Tatro, J.B.4    Fitzgerald, K.A.5    Beasley, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.