5-Benzyloxytryptamine as an antagonist of TRPM8

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 7076-7079

  Defalco, Jeff ^a   Steiger, Daniel ^a   Dourado, Michelle ^a   Emerling, Daniel ^a   Duncton, Matthew A J ^a  

^a EVOTEC AG   (Germany)

Author keywords

5 Benzyloxytryptamine; Antagonist; Icilin; Menthol; Transient receptor potential; TRP; TRPM8

Indexed keywords

5 BENZYLOXYTRYPTAMINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8 ANTAGONIST; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; STRUCTURE ANALYSIS;

ANIMALS; HUMANS; INHIBITORY CONCENTRATION 50; MENTHOL; SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRPM CATION CHANNELS; TRYPTAMINES;

EID: 78149279962     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.099     Document Type: Article

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