Synthesis, biological evaluation and radiolabelling by 18F- fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 6933-6937

  Hofling S B ^a   Maschauer, S ^b   Hubner H ^a   Gmeiner, P ^a   Wester, H J ^c   Prante, O ^b   Heinrich, M R ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

18 Fluorine; Dopamine; Ligands; Positron emission tomography; Radiochemical labelling

Indexed keywords

DIAZONIUM COMPOUND; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; FLUORINE 18; LIGAND; POLYCYCLIC AROMATIC HYDROCARBON; SEROTONIN 1A RECEPTOR; SEROTONIN 2 RECEPTOR; SH 317; SH 317 F 18; ST 168; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ARYLATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RAT; REACTION ANALYSIS;

ANIMALS; BRAIN; DOPAMINE; FLUORINE RADIOISOTOPES; ISOTOPE LABELING; LIGANDS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; RECEPTORS, DOPAMINE D3;

EID: 78149279657     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.142     Document Type: Article

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