Discovery of a dopamine D4 selective PET ligand candidate taking advantage of a click chemistry based REM linker

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 983-988

  Tietze, Rainer ^a   Löber, Stefan ^b   Hübner, Harald ^b   Gmeiner, Peter ^b   Kuwert, Torsten ^a   Prante, Olaf ^a  

^a Clinic of Nuclear Medicine   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Click chemistry; D2 like dopamine receptors; F 18; PET; Positron emission tomography; SPOS

Indexed keywords

DOPAMINE 4 RECEPTOR; FLUORINE 18; INDOLE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RADIOISOTOPE; RADIOLIGAND; RESIN; TRIAZOLYLMETHYL ACRYLATE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMISTRY; LIGAND BINDING; POSITRON EMISSION TOMOGRAPHY; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AZA COMPOUNDS; COMBINATORIAL CHEMISTRY TECHNIQUES; FLUORINE RADIOISOTOPES; HUMANS; INDOLES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, DOPAMINE D4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38749121328     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.026     Document Type: Article

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