Synthesis and radiolabeling of N-[4-[4-(2-[11C]methoxyphenyl)piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide - a potential radiotracer for D3 receptor imaging with PET

Nuclear Medicine and Biology

Volumn 33, Issue 6, 2006, Pages 785-795

  Kuhnast, Bertrand ^a   Valette, Héric ^a   Besret, Laurent ^a   Demphel, Stéphane ^a   Coulon, Christine ^a   Ottaviani, Michèle ^a   Guillermier, Martine ^a   Bottlaender, Michel ^a   Dollé, Frédéric ^a  

^a DIF   (France)

Author keywords

Carbon 11; D3 receptors; Positron emission tomography

Indexed keywords

ACETONE; CARBON 14; CARBON DIOXIDE; DOPAMINE 3 RECEPTOR; DRUG METABOLITE; FAUC 346; N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL]BENZO[B]THIOPHENE 2 CARBOXAMIDE C 11; RADIOLIGAND; SODIUM HYDROXIDE; TRACER; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BRAIN; CONTROLLED STUDY; DEVICE; DRUG FORMULATION; DRUG PURIFICATION; DRUG SELECTIVITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGING; IN VIVO STUDY; ISOTOPE LABELING; MALE; METABOLITE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIMATE; RADIOACTIVITY; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TEMPERATURE;

ANIMALS; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOTOPE LABELING; MALE; PAPIO; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D3; THIOPHENES;

EID: 33747367972     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2006.05.007     Document Type: Article

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