A concise and convergent synthesis of PA-824

Journal of Organic Chemistry

Volumn 75, Issue 21, 2010, Pages 7479-7482

  Marsini, Maurice A ^a   Reider, Paul J ^a   Sorensen, Erik J ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONVERGENT SYNTHESIS; DRUG CANDIDATES; FOUR-STEP SYNTHESIS; LARGE-SCALE PRODUCTION; SYNTHETIC ROUTES;

3 (2 CHLORO 4 NITRO 1H IMIDAZOL 1 YL) 2 (4 (TRIFLUORO METHOXY)BENZYLOXY)PROPYL 4 METHOXYBENZOATE; 3 CHLORO 2 (4 (TRIFLUOROMETHOXY)BENZYLOXY)PROPYL 4 METHOXYBENZOATE; 3 CHLORO 2 HYDROXYPROPYL 4 METHOXYBENZOATE; 4 (TRIFLUOROMETHOXY)BENZYL TRICHLOROACETIMIDATE; 6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; MYCOLIC ACID; NITROIMIDAZOLE; OXAZINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; MULTIDRUG RESISTANCE; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DRUG RESISTANCE, MULTIPLE; HYDROLYSIS; KINETICS; NITROIMIDAZOLES; STEREOISOMERISM;

EID: 78049521963     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo1015807     Document Type: Article

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