Intermediates in the reduction of the antituberculosis drug PA-824, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b] [1,3]oxazine, in aqueous solution

Organic and Biomolecular Chemistry

Volumn 6, Issue 11, 2008, Pages 1973-1980

  Anderson, Robert F ^a,b   Shinde, Sujata S ^a,b   Maroz, Andrej ^a   Boyd, Maruta ^b   Palmer, Brian D ^b   Denny, William A ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; ELECTRON TRANSITIONS; FUNCTIONAL GROUPS; RADIOLYSIS; REDOX REACTIONS;

ANTITUBERCULOSIS DRUGS; DIHYDROOXAZINE COMPOUNDS; ELECTRON TRANSFER; STEADY-STATE RADIOLYSIS;

DRUG PRODUCTS;

6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; NITROIMIDAZOLE DERIVATIVE; TUBERCULOSTATIC AGENT; WATER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; SOLUTION AND SOLUBILITY; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTITUBERCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NITROIMIDAZOLES; OXIDATION-REDUCTION; SOLUTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; WATER;

EID: 43749100470     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b801859f     Document Type: Article

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