메뉴 건너뛰기




Volumn 3, Issue 5, 2010, Pages 801-807

Knockdown of Beclin 1 inhibits vitamin K3-induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells

Author keywords

Apoptosis; Autophagy; Beclin 1; Human hepatoma cells; RNA interference; Transfection; Vitamin K3

Indexed keywords

BECLIN 1; CASPASE 3; CYCLIN DEPENDENT KINASE 4; MENADIONE; PROTEIN BCL 2; PROTEIN BCL XL; SMALL INTERFERING RNA;

EID: 78049490338     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2010.347     Document Type: Article
Times cited : (8)

References (28)
  • 4
    • 0344211514 scopus 로고    scopus 로고
    • Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells
    • DOI 10.1016/S0024-3205(03)00188-7
    • Markovits J, Wang Z, Carr BI, Sun TP, Mintz P, Le Bret M, Wu CW and Wu FY: Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells. Life Sci 72: 2769-2784, 2003. (Pubitemid 36385081)
    • (2003) Life Sciences , vol.72 , Issue.24 , pp. 2769-2784
    • Markovits, J.1    Wang, Z.2    Carr, B.I.3    Sun, T.P.4    Mintz, P.5    Le Bret, M.6    Wu, C.-W.7    Wu, F.Y.-H.8
  • 5
    • 0032841904 scopus 로고    scopus 로고
    • 3) is mediated by the Fas/Fas ligand system
    • DOI 10.1006/clim.1999.4757
    • Caricchio R, Kovalenko D, Kaufmann WK and Cohen PL: Apoptosis provoked by the oxidative stress inducer menadione (Vitamin K(3)) is mediated by the Fas/Fas ligand system. Clin Immunol 93: 65-74, 1999. (Pubitemid 29459963)
    • (1999) Clinical Immunology , vol.93 , Issue.1 , pp. 65-74
    • Caricchio, R.1    Kovalenko, D.2    Kaufmann, W.K.3    Cohen, P.L.4
  • 6
    • 35148874285 scopus 로고    scopus 로고
    • Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells
    • Ogawa M, Nakai S, Deguchi A, Nonomura T, Masaki T, Uchida N N, Yoshiji H and Kuriyama S: Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells. Int J Oncol 31: 323-331, 2007.
    • (2007) Int J Oncol , vol.31 , pp. 323-331
    • Ogawa, M.1    Nakai, S.2    Deguchi, A.3    Nonomura, T.4    Masaki, T.5    Uchida, N.N.6    Yoshiji, H.7    Kuriyama, S.8
  • 7
    • 70349617472 scopus 로고    scopus 로고
    • The potential of vitamin K3 as an anticancer agent against breast cancer that acts via the mitochondria-related apoptotic pathway
    • Akiyoshi T, Matzno S, Sakai M, Okamura N and Matsuyama K: The potential of vitamin K3 as an anticancer agent against breast cancer that acts via the mitochondria-related apoptotic pathway. Cancer Chemother Pharmacol 65: 143-150, 2009.
    • (2009) Cancer Chemother Pharmacol , vol.65 , pp. 143-150
    • Akiyoshi, T.1    Matzno, S.2    Sakai, M.3    Okamura, N.4    Matsuyama, K.5
  • 9
    • 0037451783 scopus 로고    scopus 로고
    • Autophagy: A barrier or an adaptive response to cancer
    • Ogier-Denis E and Codogno P: Autophagy: a barrier or an adaptive response to cancer. Biochim Biophys Acta 1603: 113-128, 2003.
    • (2003) Biochim Biophys Acta , vol.1603 , pp. 113-128
    • Ogier-Denis, E.1    Codogno, P.2
  • 10
    • 0034948738 scopus 로고    scopus 로고
    • The autophagosomal-lysosomal compartment in programmed cell death
    • DOI 10.1038/sj.cdd.4400852
    • Bursch W: The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ 8: 569-581, 2001. (Pubitemid 32590778)
    • (2001) Cell Death and Differentiation , vol.8 , Issue.6 , pp. 569-581
    • Bursch, W.1
  • 12
    • 0034012322 scopus 로고    scopus 로고
    • Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments
    • Bursch W, Hochegger K, Török L, Marian B and Ellinger A: Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments. J Cell Sci 113: 1189-1198, 2000. (Pubitemid 30229536)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1189-1198
    • Bursch, W.1    Hochegger, K.2    Torok, L.3    Marian, B.4    Ellinger, A.5    Hermann, R.S.6
  • 13
    • 4344673498 scopus 로고    scopus 로고
    • Mechanisms of chaperone-mediated autophagy
    • Majeski AE and Dice JF: Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol 36: 2435-2444, 2004.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2435-2444
    • Majeski, A.E.1    Dice, J.F.2
  • 14
    • 67650727404 scopus 로고    scopus 로고
    • Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells
    • Zhang H, Kong X, Kang J, Su J, Li Y, Zhong J and Sun L: Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells. Toxicol Sci 110: 376-388, 2009.
    • (2009) Toxicol Sci , vol.110 , pp. 376-388
    • Zhang, H.1    Kong, X.2    Kang, J.3    Su, J.4    Li, Y.5    Zhong, J.6    Sun, L.7
  • 16
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue Z, Jin S, Yang C, Levine AJ and Heintz N: Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 100: 15077-15082, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5
  • 20
    • 19544373434 scopus 로고    scopus 로고
    • Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity
    • Furuya D, Tsuji N, Yagihashi A and Watanabe N: Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity. Exp Cell Res 307: 26-40, 2005.
    • (2005) Exp Cell Res , vol.307 , pp. 26-40
    • Furuya, D.1    Tsuji, N.2    Yagihashi, A.3    Watanabe, N.4
  • 21
    • 0028836002 scopus 로고
    • Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
    • Biederbick A, Kern HF and Elsasser HP: Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol 66: 3-14, 1995.
    • (1995) Eur J Cell Biol , vol.66 , pp. 3-14
    • Biederbick, A.1    Kern, H.F.2    Elsasser, H.P.3
  • 22
    • 67650305520 scopus 로고    scopus 로고
    • Regulation of Beclin 1 in autophagy
    • Sun Q, Fan W and Zhong Q: Regulation of Beclin 1 in autophagy. Autophagy 5: 713-716, 2009.
    • (2009) Autophagy , vol.5 , pp. 713-716
    • Sun, Q.1    Fan, W.2    Zhong, Q.3
  • 24
    • 0032841904 scopus 로고    scopus 로고
    • Apoptosis provoked by the oxidative stress inducer menadione (Vitamin K3) is mediated by the Fas/Fas ligand system
    • Caricchio R, Kovalenko D, Kaufmann WK and Cohen PL: Apoptosis provoked by the oxidative stress inducer menadione (Vitamin K3) is mediated by the Fas/Fas ligand system. Clin Immunol 93: 65-74, 1999.
    • (1999) Clin Immunol , vol.93 , pp. 65-74
    • Caricchio, R.1    Kovalenko, D.2    Kaufmann, W.K.3    Cohen, P.L.4
  • 25
    • 1542350182 scopus 로고    scopus 로고
    • Resistance of mitochondrial DNA -depleted cells against cell death: Role of mitochondrial superoxide dismutase
    • Park SY, Chang I, Kim JY, Kang SW, Park SH, Singh K and Lee MS: Resistance of mitochondrial DNA -depleted cells against cell death: role of mitochondrial superoxide dismutase. J Biol Chem 279: 7512-7520, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 7512-7520
    • Park, S.Y.1    Chang, I.2    Kim, J.Y.3    Kang, S.W.4    Park, S.H.5    Singh, K.6    Lee, M.S.7
  • 26
    • 0035881870 scopus 로고    scopus 로고
    • Autophagy delays sulindac sulfide-induced apoptosis in the humanintestinal colon cancer cell line HT-29
    • Bauvy C, Gane P, Arico S, Codogno P and Ogier-Denis E: Autophagy delays sulindac sulfide-induced apoptosis in the humanintestinal colon cancer cell line HT-29. Exp Cell Res 268: 139-149, 2001.
    • (2001) Exp Cell Res , vol.268 , pp. 139-149
    • Bauvy, C.1    Gane, P.2    Arico, S.3    Codogno, P.4    Ogier-Denis, E.5
  • 27
    • 34250822045 scopus 로고    scopus 로고
    • Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells
    • González-Polo RA , Niso-Santano M, Ortíz-Ortíz MA, et al: Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells. Toxicol Sci 97: 448-458, 2007.
    • (2007) Toxicol Sci , vol.97 , pp. 448-458
    • González-Polo, R.A.1    Niso-Santano, M.2    Ortíz, M.A.3
  • 28


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.