The potential of vitamin K3 as an anticancer agent against breast cancer that acts via the mitochondria-related apoptotic pathway

Cancer Chemotherapy and Pharmacology

Volumn 65, Issue 1, 2009, Pages 143-150

  Akiyoshi, Takeshi ^a   Matzno, Sumio ^b   Sakai, Mika ^b   Okamura, Noboru ^b,c   Matsuyama, Kenji ^a  

^a KEIO UNIVERSITY   (Japan)

^b MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^c Mukogawa Women's University   (Japan)

Author keywords

Breast cancer; Mitochondrial dysfunction; ROS; Vitamin K3

Indexed keywords

CASPASE 7; CASPASE 9; ESTERASE; MENADIONE; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT;

AGAR GEL ELECTROPHORESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; BREAST TUMOR; DRUG EFFECT; DRUG SCREENING; FEMALE; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 7; CASPASE 9; CELL LINE, TUMOR; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, AGAR GEL; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; VITAMIN K 3;

EID: 70349617472     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-009-1016-7     Document Type: Article

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