메뉴 건너뛰기




Volumn 31, Issue 2, 2007, Pages 323-331

Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells

Author keywords

Antitumor effect; Apoptosis; Caspase; Colorectal cancer; Vitamin K

Indexed keywords

4 AMINO 2 METHYL 1 NAPHTHOL; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; FARNOQUINONE; FLUORESCEIN ISOTHIOCYANATE; MENADIONE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

EID: 35148874285     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.31.2.323     Document Type: Article
Times cited : (49)

References (51)
  • 1
    • 4444244978 scopus 로고    scopus 로고
    • International variation
    • Parkin DM: International variation. Oncogene 23: 6329-6340, 2004.
    • (2004) Oncogene , vol.23 , pp. 6329-6340
    • Parkin, D.M.1
  • 2
    • 0034767957 scopus 로고    scopus 로고
    • Cancer burden in the year 2000. The global picture
    • Parkin D, Bray F and Devesa S: Cancer burden in the year 2000. The global picture. Eur J Cancer 37: 64-66, 2001.
    • (2001) Eur J Cancer , vol.37 , pp. 64-66
    • Parkin, D.1    Bray, F.2    Devesa, S.3
  • 5
    • 0016812082 scopus 로고
    • The functional significance of vitamin K action. Difference in phospholipid binding between normal and abnormal prothrombin
    • Esmon CT, Suttie JW and Jackson CM: The functional significance of vitamin K action. Difference in phospholipid binding between normal and abnormal prothrombin. J Biol Chem 250: 4095-4099, 1975.
    • (1975) J Biol Chem , vol.250 , pp. 4095-4099
    • Esmon, C.T.1    Suttie, J.W.2    Jackson, C.M.3
  • 6
    • 0018760191 scopus 로고
    • Vitamin K-dependent gamma-glutamyl carboxylase activity in the chick embryonic chorioallantoic membrane
    • Tuan RS: Vitamin K-dependent gamma-glutamyl carboxylase activity in the chick embryonic chorioallantoic membrane. J Biol Chem 254: 1356-1364, 1979.
    • (1979) J Biol Chem , vol.254 , pp. 1356-1364
    • Tuan, R.S.1
  • 8
    • 0037155472 scopus 로고    scopus 로고
    • Vitamin K uptake in hepatocytes and hepatoma cells
    • DOI 10.1016/S0024-3205(01)01525-9, PII S0024320501015259
    • Li ZQ, He FY, Stehle CJ, Wang Z, Kar S, Finn FM and Carr BI: Vitamin K uptake in hepatocytes and hepatoma cells. Life Sci 70: 2085-2100, 2002. (Pubitemid 34219460)
    • (2002) Life Sciences , vol.70 , Issue.18 , pp. 2085-2100
    • Li, Z.-Q.1    He, F.-Y.2    Stehle, C.J.3    Wang, Z.4    Kar, S.5    Finn, F.M.6    Carr, B.I.7
  • 9
    • 0013800109 scopus 로고    scopus 로고
    • Vitamin K5 as a fungistatic agent
    • Merrifield LS and Yang HY: Vitamin K5 as a fungistatic agent. Appl Microbiol 13: 660-662, 2002.
    • (2002) Appl Microbiol , vol.13 , pp. 660-662
    • Merrifield, L.S.1    Yang, H.Y.2
  • 10
    • 0022177817 scopus 로고
    • Inhibition of down regulation by chloroquine in cultured lymphocytes (RPMI-1788 line)
    • DOI 10.1016/S0168-8227(85)80004-8
    • Maegawa H, Kobayashi M, Watanabe N, Ishibashi O, Takata Y and Shigeta Y: Inhibition of down regulation by chloroquine in cultured lymphocytes (RPMI-1788 line). Diabetes Res Clin Pract 1: 145-153, 1985. (Pubitemid 17036322)
    • (1985) Diabetes Research and Clinical Practice , vol.1 , Issue.3 , pp. 145-153
    • Maegawa, H.1    Kobayashi, M.2    Watanabe, N.3
  • 11
    • 0023881754 scopus 로고    scopus 로고
    • Insulin receptor and postbinding defects in KK mouse adipocytes and improvement by ciglitazone
    • Taketomi S, Fujita T and Yokono K: Insulin receptor and postbinding defects in KK mouse adipocytes and improvement by ciglitazone. Diabetes Res Clin Pract 5: 125-134, 1998.
    • (1998) Diabetes Res Clin Pract , vol.5 , pp. 125-134
    • Taketomi, S.1    Fujita, T.2    Yokono, K.3
  • 12
    • 0029148360 scopus 로고
    • The growth inhibitory effects of vitamins K and their actions on gene expression
    • Wang Z, Wang M, Finn F and Carr BI: The growth inhibitory effects of vitamins K and their actions on gene expression. Hepatology 22: 876-882, 1995.
    • (1995) Hepatology , vol.22 , pp. 876-882
    • Wang, Z.1    Wang, M.2    Finn, F.3    Carr, B.I.4
  • 13
    • 0344211514 scopus 로고    scopus 로고
    • Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells
    • Markovits J, Wang Z, Carr BI, Sun TP, Mintz P, Le Bret M, Wu CW and Wu FY: Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells. Life Sci 72: 2769-2784, 2003.
    • (2003) Life Sci , vol.72 , pp. 2769-2784
    • Markovits, J.1    Wang, Z.2    Carr, B.I.3    Sun, T.P.4    Mintz, P.5    Le Bret, M.6    Wu, C.W.7    Wu, F.Y.8
  • 15
    • 0026100509 scopus 로고
    • Menadione: Spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines
    • Nutter LM, Cheng AL, Hung HL, Hsieh RK, Ngo EO and Liu TW: Menadione: spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines. Biochem Pharmacol 41: 1283-1292, 1991.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1283-1292
    • Nutter, L.M.1    Cheng, A.L.2    Hung, H.L.3    Hsieh, R.K.4    Ngo, E.O.5    Liu, T.W.6
  • 16
    • 30444456208 scopus 로고    scopus 로고
    • Effects of a naphthoquinone analog on tumor growth and apoptosis induction
    • Kim HJ, Mun JY, Chun YJ, Choi KH, Ham SW and Kim MY: Effects of a naphthoquinone analog on tumor growth and apoptosis induction. Arch Pharm Res 26: 405-410, 2003.
    • (2003) Arch Pharm Res , vol.26 , pp. 405-410
    • Kim, H.J.1    Mun, J.Y.2    Chun, Y.J.3    Choi, K.H.4    Ham, S.W.5    Kim, M.Y.6
  • 17
    • 0042919084 scopus 로고    scopus 로고
    • The anticancer effects of vitamin K
    • Lamson DW and Plaza SM: The anticancer effects of vitamin K. Altern Med Rev 8: 303-318, 2003.
    • (2003) Altern Med Rev , vol.8 , pp. 303-318
    • Lamson, D.W.1    Plaza, S.M.2
  • 18
    • 0028618303 scopus 로고
    • Novel role of vitamin K2: A potent inducer of differentiation of various human myeloid leukemia cell lines
    • Sakai I, Hashimoto S, Yoda M, Hida T, Ohsawa S, Nakajo S and Nakaya K: Novel role of vitamin K2: a potent inducer of differentiation of various human myeloid leukemia cell lines. Biochem Biophys Res Commun 205: 1305-1310, 1994.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1305-1310
    • Sakai, I.1    Hashimoto, S.2    Yoda, M.3    Hida, T.4    Ohsawa, S.5    Nakajo, S.6    Nakaya, K.7
  • 19
    • 0029559839 scopus 로고
    • Growth control and gene expression in a new hepatocellular carcinoma cell line, Hep40: Inhibitory actions of vitamin K
    • DOI 10.1002/jcp.1041650303
    • Bouzahzah B, Nishikawa Y, Simon D and Carr BI: Growth control and gene expression in a new hepatocellular carcinoma cell line, Hep40: inhibitory actions of vitamin K. J Cell Physiol 165: 459-467, 1995. (Pubitemid 26004303)
    • (1995) Journal of Cellular Physiology , vol.165 , Issue.3 , pp. 459-467
    • Bouzahzah, B.1    Nishikawa, Y.2    Simon, D.3    Carr, B.I.4
  • 20
    • 0030994450 scopus 로고    scopus 로고
    • Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid
    • Yaguchi M, Miyazawa K, Katagiri T, Nishimaki J, Kizaki M, Tohyama K and Toyama K: Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid. Leukemia 11: 779-787, 1997.
    • (1997) Leukemia , vol.11 , pp. 779-787
    • Yaguchi, M.1    Miyazawa, K.2    Katagiri, T.3    Nishimaki, J.4    Kizaki, M.5    Tohyama, K.6    Toyama, K.7
  • 21
    • 17344363486 scopus 로고    scopus 로고
    • Vitamin K2 selectively induces apoptosis of blastic cells in myelodysplastic syndrome: Flow cytometric detection of apoptotic cells using APO2.7 monoclonal antibody
    • Yaguchi M, Miyazawa K, Otawa M, Katagiri T, Nishimaki J, Uchida Y, Iwase O, Gotoh A, Kawanishi Y and Toyama K: Vitamin K2 selectively induces apoptosis of blastic cells in myelodysplastic syndrome: flow cytometric detection of apoptotic cells using APO2.7 monoclonal antibody. Leukemia 12: 1392-1397, 1998.
    • (1998) Leukemia , vol.12 , pp. 1392-1397
    • Yaguchi, M.1    Miyazawa, K.2    Otawa, M.3    Katagiri, T.4    Nishimaki, J.5    Uchida, Y.6    Iwase, O.7    Gotoh, A.8    Kawanishi, Y.9    Toyama, K.10
  • 23
    • 0033939553 scopus 로고    scopus 로고
    • Cytotoxic effect through Fas/APO-1 expression due to vitamin K in human glioma cells
    • DOI 10.1023/A:1006443422488
    • Sun LK, Yoshii Y and Miyagi K: Cytotoxic effect through fas/Apo-1 expression due to vitamin K in human glioma cells. J Neurooncol 47: 31-38, 2000. (Pubitemid 30458403)
    • (2000) Journal of Neuro-Oncology , vol.47 , Issue.1 , pp. 31-38
    • Sun, L.-K.1    Yoshii, Y.2    Miyagi, K.3
  • 25
    • 0025272678 scopus 로고
    • Molecular basis of vitamin K-dependent gamma-carboxylation
    • Furie B and Furie BC: Molecular basis of vitamin K-dependent gamma-carboxylation. Blood 75: 1753-1762, 1990. (Pubitemid 20161485)
    • (1990) Blood , vol.75 , Issue.9 , pp. 1753-1762
    • Furie, B.1    Furie, B.C.2
  • 26
    • 0027516607 scopus 로고
    • Comparison of antitumor activity of vitamins K1, K2 and K3 on human tumor cells by two (MTT and SRB) cell viability assays
    • Wu FY, Liao WC and Chang HM: Comparison of antitumor activity of vitamins K1, K2 and K3 on human tumor cells by two (MTT and SRB) cell viability assays. Life Sci 52: 1797-1804, 1993.
    • (1993) Life Sci , vol.52 , pp. 1797-1804
    • Wu, F.Y.1    Liao, W.C.2    Chang, H.M.3
  • 28
    • 0037722974 scopus 로고    scopus 로고
    • The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy
    • Verrax L, Cadrobbi J, Delvaux M, Jamison JM, Gilloteaux J, Summers JL, Taper HS and Buc Calderon P: The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy. Eur J Med Chem 38: 451-457, 2003.
    • (2003) Eur J Med Chem , vol.38 , pp. 451-457
    • Verrax, L.1    Cadrobbi, J.2    Delvaux, M.3    Jamison, J.M.4    Gilloteaux, J.5    Summers, J.L.6    Taper, H.S.7    Buc Calderon, P.8
  • 29
    • 0023812307 scopus 로고    scopus 로고
    • Inhibition of the redox cycling of vitamin K3 (menadione) in mouse liver microsomes
    • Byczkowski JZ and Gessner T: Inhibition of the redox cycling of vitamin K3 (menadione) in mouse liver microsomes. Int J Biochem 20: 1073-1079, 1998.
    • (1998) Int J Biochem , vol.20 , pp. 1073-1079
    • Byczkowski, J.Z.1    Gessner, T.2
  • 30
    • 0021893435 scopus 로고
    • 3 inhibition of malignant murine cell growth and human tumor colony formation
    • Chlebowski RT, Dietrich M, Akman S and Block JB: Vitamin K3 inhibition of malignant murine cell growth and human tumor colony formation. Cancer Treat Rep 69: 527-532, 1985. (Pubitemid 15031402)
    • (1985) Cancer Treatment Reports , vol.69 , Issue.5 , pp. 527-532
    • Chlebowski, R.T.1    Dietrich, M.2    Akman, S.3    Block, J.B.4
  • 32
    • 0021028643 scopus 로고
    • Characterization of metastatic clones derived from a metastatic variant of mouse colon adenocarcinoma 26
    • Tsuruo T, Yamori T, Naganuma K, Tsukagoshi S and Sakurai Y: Characterization of metastatic clones derived from a metastatic variant of mouse colon adenocarcinoma 26. Cancer Res 43: 5437-5442, 1983. (Pubitemid 14230162)
    • (1983) Cancer Research , vol.43 , Issue.11 , pp. 5437-5442
    • Tsuruo, T.1    Yamori, T.2    Naganuma, K.3
  • 34
    • 0028967988 scopus 로고
    • Synergistic roles of granzymes a and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin
    • Nakajima H, Park HL and Henkart PA: Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin. J Exp Med 181: 1037-1046, 1995.
    • (1995) J Exp Med , vol.181 , pp. 1037-1046
    • Nakajima, H.1    Park, H.L.2    Henkart, P.A.3
  • 36
    • 0037220012 scopus 로고    scopus 로고
    • Osteopontin and colon cancer progression
    • Yeatman TJ and Chambers AF: Osteopontin and colon cancer progression. Clin Exp Metastasis 20: 85-90, 2003.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 85-90
    • Yeatman, T.J.1    Chambers, A.F.2
  • 37
    • 0031428574 scopus 로고    scopus 로고
    • Quinone-induced DNA single strand breaks in a human colon carcinoma cell line
    • DOI 10.1093/carcin/18.1.43
    • D'Odorico A, Sturniolo GC, Bilton RF, Morris AI, Gilmore IT and Naccarato R: Quinone-induced DNA single strand breaks in a human colon carcinoma cell line. Carcinogenesis 18: 43-46, 1997. (Pubitemid 28134615)
    • (1997) Carcinogenesis , vol.18 , Issue.1 , pp. 43-46
    • D'Odorico, A.1    Sturniolo, G.C.2    Bilton, R.F.3    Morris, A.I.4    Gilmore, I.T.5    Naccarato, R.6
  • 39
    • 3142708765 scopus 로고    scopus 로고
    • Role of vitamin K2 in the development of hepatocellular carcinoma in women with viral cirrhosis of the liver
    • Habu D, Shiomi S, Tamori A, Takeda T, Tanaka T, Kubo S and Nishiguchi S: Role of vitamin K2 in the development of hepatocellular carcinoma in women with viral cirrhosis of the liver. JAMA 292: 358-361, 2004.
    • (2004) JAMA , vol.292 , pp. 358-361
    • Habu, D.1    Shiomi, S.2    Tamori, A.3    Takeda, T.4    Tanaka, T.5    Kubo, S.6    Nishiguchi, S.7
  • 40
    • 32544446614 scopus 로고    scopus 로고
    • The effect of menatetrenone, a vitamin K2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: A pilot study
    • Mizuta T, Ozaki I, Eguchi Y, Yasutake T, Kawazoe S, Fujimoto K and Yamamoto K: The effect of menatetrenone, a vitamin K2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: a pilot study. Cancer 106: 867-872, 2006.
    • (2006) Cancer , vol.106 , pp. 867-872
    • Mizuta, T.1    Ozaki, I.2    Eguchi, Y.3    Yasutake, T.4    Kawazoe, S.5    Fujimoto, K.6    Yamamoto, K.7
  • 44
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM: Caspases: the executioners of apoptosis. Biochem J 326: 1-16, 1997.
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 45
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA and Lazebnik Y: Caspases: enemies within. Science 281: 1312-1316, 1998.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 46
    • 0036054309 scopus 로고    scopus 로고
    • Combination of 22-oxa-1,25-dihydroxyvitamin D3, a vitamin D3 derivative, with vitamin K2 (VK2) synergistically enhances cell differentiation but suppresses VK2-inducing apoptosis in HL-60 cells
    • Funato K, Miyazawa K, Yaguchi M, Gotoh A and Ohyashiki K: Combination of 22-oxa-1,25-dihydroxyvitamin D3, a vitamin D3 derivative, with vitamin K2 (VK2) synergistically enhances cell differentiation but suppresses VK2-inducing apoptosis in HL-60 cells. Leukemia 16: 1519-1527, 2002.
    • (2002) Leukemia , vol.16 , pp. 1519-1527
    • Funato, K.1    Miyazawa, K.2    Yaguchi, M.3    Gotoh, A.4    Ohyashiki, K.5
  • 48
    • 0034242787 scopus 로고    scopus 로고
    • Binary/ternary combined effects of vitamin K3 with other antitumor agents in nasopharyngeal carcinoma CG1 cells
    • Liao WC, Wu FY and Wu CW: Binary/ternary combined effects of vitamin K3 with other antitumor agents in nasopharyngeal carcinoma CG1 cells. Int J Oncol 17: 323-328, 2000.
    • (2000) Int J Oncol , vol.17 , pp. 323-328
    • Liao, W.C.1    Wu, F.Y.2    Wu, C.W.3
  • 49
    • 0022907585 scopus 로고
    • In vivo synergy of vitamin K3 and methotrexate in tumor-bearing animals
    • Gold J: In vivo synergy of vitamin K3 and methotrexate in tumor-bearing animals. Cancer Treat Rep 70: 1433-1435, 1986.
    • (1986) Cancer Treat Rep , vol.70 , pp. 1433-1435
    • Gold, J.1
  • 50
    • 20144389070 scopus 로고    scopus 로고
    • Combination of vitamin K2 and the angiotensin-converting enzyme inhibitor, peridopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression
    • Yoshiji H, Kuriyama S, Noguchi R, Yoshii J, Ikenaka Y, Yanase K, Namisaki T, Kitade M, Yamazaki M, Masaki T and Fukui H: Combination of vitamin K2 and the angiotensin-converting enzyme inhibitor, peridopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression. J Hepatol 42: 687-693, 2005.
    • (2005) J Hepatol , vol.42 , pp. 687-693
    • Yoshiji, H.1    Kuriyama, S.2    Noguchi, R.3    Yoshii, J.4    Ikenaka, Y.5    Yanase, K.6    Namisaki, T.7    Kitade, M.8    Yamazaki, M.9    Masaki, T.10    Fukui, H.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.