-
1
-
-
65549129496
-
Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases
-
C.D. Packey, and R.B. Sartor Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases Curr Opin Infect Dis 22 2009 292 301
-
(2009)
Curr Opin Infect Dis
, vol.22
, pp. 292-301
-
-
Packey, C.D.1
Sartor, R.B.2
-
2
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
J.P. Hugot, M. Chamaillard, and H. Zouali Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 411 2001 599 603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
3
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Y. Ogura, D.K. Bonen, and N. Inohara A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 411 2001 603 606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
-
4
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
J. Hampe, A. Cuthbert, and P.J. Croucher Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations Lancet 357 2001 1925 1928
-
(2001)
Lancet
, vol.357
, pp. 1925-1928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.J.3
-
5
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2: Implications for Crohn's disease
-
N. Inohara, Y. Ogura, and A. Fontalba Host recognition of bacterial muramyl dipeptide mediated through NOD2 Implications for Crohn's disease J Biol Chem 278 2003 5509 5512
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
-
6
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
K.S. Kobayashi, M. Chamaillard, and Y. Ogura Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract Science 307 2005 731 734
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
7
-
-
70349468054
-
Nod2 is required for the regulation of commensal microbiota in the intestine
-
T. Petnicki-Ocwieja, T. Hrncir, and Y.J. Liu Nod2 is required for the regulation of commensal microbiota in the intestine Proc Natl Acad Sci U S A 106 2009 15813 15818
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 15813-15818
-
-
Petnicki-Ocwieja, T.1
Hrncir, T.2
Liu, Y.J.3
-
8
-
-
78049450786
-
The protein NOD2: An innate receptor more complex than previously assumed
-
A. Lecat, J. Piette, and S. Legrand-Poels The protein NOD2: an innate receptor more complex than previously assumed Biochem Pharmacol 2010 Jul 17 [Epub ahead of print]
-
(2010)
Biochem Pharmacol
-
-
Lecat, A.1
Piette, J.2
Legrand-Poels, S.3
-
9
-
-
70449722759
-
T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii
-
M.H. Shaw, T. Reimer, and C. Sanchez-Valdepenas T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii Nat Immunol 10 2009 1267 1274
-
(2009)
Nat Immunol
, vol.10
, pp. 1267-1274
-
-
Shaw, M.H.1
Reimer, T.2
Sanchez-Valdepenas, C.3
-
10
-
-
38849163741
-
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis
-
T. Watanabe, N. Asano, and P.J. Murray Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis J Clin Invest 118 2008 545 559
-
(2008)
J Clin Invest
, vol.118
, pp. 545-559
-
-
Watanabe, T.1
Asano, N.2
Murray, P.J.3
-
11
-
-
39149094587
-
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands
-
Y.G. Kim, J.H. Park, and M.H. Shaw The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands Immunity 28 2008 246 257
-
(2008)
Immunity
, vol.28
, pp. 246-257
-
-
Kim, Y.G.1
Park, J.H.2
Shaw, M.H.3
-
12
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
S. Maeda, L.C. Hsu, and H. Liu Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing Science 307 2005 734 738
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
-
13
-
-
65249115914
-
A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1
-
E. Noguchi, Y. Homma, and X. Kang A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1 Nat Immunol 10 2009 471 479
-
(2009)
Nat Immunol
, vol.10
, pp. 471-479
-
-
Noguchi, E.1
Homma, Y.2
Kang, X.3
-
14
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
J.C. Barrett, S. Hansoul, and D.L. Nicolae Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Nat Genet 40 2008 955 962
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
15
-
-
65249108735
-
Autophagy genes in immunity
-
H.W. Virgin, and B. Levine Autophagy genes in immunity Nat Immunol 10 2009 461 470
-
(2009)
Nat Immunol
, vol.10
, pp. 461-470
-
-
Virgin, H.W.1
Levine, B.2
-
16
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
P. Kuballa, A. Huett, and J.D. Rioux Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant PLoS ONE 3 2008 e3391
-
(2008)
PLoS ONE
, vol.3
, pp. 3391
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
-
17
-
-
70450248450
-
Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: Analysis of the organization of the Atg16L1 complex in fibroblasts
-
N. Fujita, T. Saitoh, and S. Kageyama Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts J Biol Chem 284 2009 32602 32609
-
(2009)
J Biol Chem
, vol.284
, pp. 32602-32609
-
-
Fujita, N.1
Saitoh, T.2
Kageyama, S.3
-
18
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
T. Saitoh, N. Fujita, and M.H. Jang Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production Nature 456 2008 264 268
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
19
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
K. Cadwell, J.Y. Liu, and S.L. Brown A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells Nature 456 2008 259 263
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
20
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines the intestinal phenotype associated with the Crohn's disease gene Atg16L1
-
K. Cadwell, K.K. Patel, and N.S. Maloney Virus-plus-susceptibility gene interaction determines the intestinal phenotype associated with the Crohn's disease gene Atg16L1 Cell 141 2010 1135 1145
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
Patel, K.K.2
Maloney, N.S.3
-
21
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
R. Cooney, J. Baker, and O. Brain NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation Nat Med 16 2010 90 97
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
22
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
L.H. Travassos, L.A. Carneiro, and M. Ramjeet Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry Nat Immunol 11 2010 55 62
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
23
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent, anti-bacterial pathway implicated in Crohn's disease pathogenesis
-
C.R. Homer, A.L. Richmond, and N.A. Rebert ATG16L1 and NOD2 interact in an autophagy-dependent, anti-bacterial pathway implicated in Crohn's disease pathogenesis Gastroenterology 139 2010 1630 1641
-
(2010)
Gastroenterology
, vol.139
, pp. 1630-1641
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
-
24
-
-
61649114427
-
A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn's disease
-
K. Cadwell, K.K. Patel, and M. Komatsu A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn's disease Autophagy 5 2008 250 252
-
(2008)
Autophagy
, vol.5
, pp. 250-252
-
-
Cadwell, K.1
Patel, K.K.2
Komatsu, M.3
-
25
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
J.H. Park, S. Wacholder, and M.H. Gail Estimation of effect size distribution from genome-wide association studies and implications for future discoveries Nat Genet 42 2010 570 575
-
(2010)
Nat Genet
, vol.42
, pp. 570-575
-
-
Park, J.H.1
Wacholder, S.2
Gail, M.H.3
|