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Volumn 2, Issue 1, 2010, Pages 225-232

Role of intranasal fentanyl in breakthrough pain management in cancer patients

Author keywords

Adverse effects; Analgesia; Breakthrough pain; Intranasal fentanyl; Opioid analgesics; Treatment

Indexed keywords

ANESTHETIC AGENT; CYTOCHROME P450 3A4; DECONGESTIVE AGENT; DRUG METABOLITE; FENTANYL; FENTANYL CITRATE; HYDROMORPHONE; KETAMINE; METHADONE; MORPHINE; NOSE SPRAY; OPIATE; OXYCODONE; PLACEBO;

EID: 78049380734     PISSN: None     EISSN: 11791322     Source Type: Book Series    
DOI: 10.2147/CMR.S7926     Document Type: Review
Times cited : (20)

References (56)
  • 1
    • 0025336568 scopus 로고
    • Breakthrough pain: Definition, prevalence and characteristics
    • Portenoy RK, Hagen NA. Breakthrough pain: Definition, prevalence and characteristics. Pain. 1990;41:273-281.
    • (1990) Pain , vol.41 , pp. 273-281
    • Portenoy, R.K.1    Hagen, N.A.2
  • 2
    • 38849169122 scopus 로고    scopus 로고
    • Bole przebijajace w chorobie nowotworowej
    • Hilgier M. Bole przebijajace w chorobie nowotworowej. Wspolcz Onkol. 2001;5:168-174.
    • (2001) Wspolcz Onkol , vol.5 , pp. 168-174
    • Hilgier, M.1
  • 3
    • 0033835177 scopus 로고    scopus 로고
    • Prevalence and characteristics of breakthrough pain in cancer patients admitted to a hospice
    • Zeppetella G, O'Doherty CA, Collins S. Prevalence and characteristics of breakthrough pain in cancer patients admitted to a hospice. J Pain Symptom Manage. 2000;20:87-92.
    • (2000) J Pain Symptom Manage , vol.20 , pp. 87-92
    • Zeppetella, G.1    O'Doherty, C.A.2    Collins, S.3
  • 4
    • 0036045991 scopus 로고    scopus 로고
    • Breakthrough cancer pain: Prevalence and characteristics in patients in Catalonia, Spain
    • Gómez-Batiste X, Madrid F, Moreno F, et al. Breakthrough cancer pain: Prevalence and characteristics in patients in Catalonia, Spain. J Pain Symptom Manage. 2000;20:45-52.
    • (2000) J Pain Symptom Manage , vol.20 , pp. 45-52
    • Gómez-Batiste, X.1    Madrid, F.2    Moreno, F.3
  • 5
    • 0032899247 scopus 로고    scopus 로고
    • Breakthrough pain: Characteristics and impact in patients with cancer pain
    • Portenoy RK, Payne D, Jacobsen P. Breakthrough pain: Characteristics and impact in patients with cancer pain. Pain. 1999;81:129-134.
    • (1999) Pain , vol.81 , pp. 129-134
    • Portenoy, R.K.1    Payne, D.2    Jacobsen, P.3
  • 6
    • 2942637938 scopus 로고    scopus 로고
    • Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey
    • Working Group of an IASP Task Force on Cancer Pain
    • Caraceni A, Martini C, Zecca E, Portenoy RK; Working Group of an IASP Task Force on Cancer Pain. Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey. Palliat Med. 2004;18:177-183.
    • (2004) Palliat Med , vol.18 , pp. 177-183
    • Caraceni, A.1    Martini, C.2    Zecca, E.3    Portenoy, R.K.4
  • 7
    • 78049378459 scopus 로고    scopus 로고
    • Characteristics and mechanisms of BTCP
    • Mercadante S. Characteristics and mechanisms of BTCP. Eur J Palliat Care. 2010;17:8-12.
    • (2010) Eur J Palliat Care , vol.17 , pp. 8-12
    • Mercadante, S.1
  • 8
    • 78049353769 scopus 로고    scopus 로고
    • Assessment of BTCP
    • Davies AN. Assessment of BTCP. Eur J Palliat Care. 2010;17:13-15.
    • (2010) Eur J Palliat Care , vol.17 , pp. 13-15
    • Davies, A.N.1
  • 9
    • 8144229465 scopus 로고    scopus 로고
    • Acute and chronic cancer pain syndromes
    • In: Doyle D, Hanks G, Cherny N, Calman K, editors. Oxford: Oxford University Press
    • Foley KM. Acute and chronic cancer pain syndromes. In: Doyle D, Hanks G, Cherny N, Calman K, editors. Oxford Textbook of Palliative Medicine. Oxford: Oxford University Press; 2004.
    • (2004) Oxford Textbook of Palliative Medicine
    • Foley, K.M.1
  • 10
    • 33845939711 scopus 로고    scopus 로고
    • Kliniczna ocena bolu w chorobie nowotworowej
    • Leppert W. Kliniczna ocena bolu w chorobie nowotworowej. Twoj Mag Med. 2005;5:34-40.
    • (2005) Twoj Mag Med , vol.5 , pp. 34-40
    • Leppert, W.1
  • 11
    • 0036468726 scopus 로고    scopus 로고
    • Episodic (Breakthrough) Pain. Consensus Conference of an Expert Working Group of the European Association for Palliative Care
    • Steering Committee of the European Association for Palliative Care (EAPC) Research Network
    • Mercadante S, Radbruch L, Caraceni A, et al; Steering Committee of the European Association for Palliative Care (EAPC) Research Network. Episodic (Breakthrough) Pain. Consensus Conference of an Expert Working Group of the European Association for Palliative Care. Cancer. 2002;94:832-839.
    • (2002) Cancer , vol.94 , pp. 832-839
    • Mercadante, S.1    Radbruch, L.2    Caraceni, A.3
  • 12
    • 61849093095 scopus 로고    scopus 로고
    • The management of cancer-related breakthrough pain: Recommendations of a Task Group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland
    • Davies AN, Dickman A, Reid C, Stevens AM, Zeppetella G. The management of cancer-related breakthrough pain: Recommendations of a Task Group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain. 2009;13: 331-338.
    • (2009) Eur J Pain , vol.13 , pp. 331-338
    • Davies, A.N.1    Dickman, A.2    Reid, C.3    Stevens, A.M.4    Zeppetella, G.5
  • 13
    • 0037758126 scopus 로고    scopus 로고
    • Morphine and alternative opioids in cancer pain: The EAPC recommendations
    • Expert Working Group of the Research Network of the European Association for Palliative Care
    • Hanks GW, de Conno F, Cherny N, et al; Expert Working Group of the Research Network of the European Association for Palliative Care. Morphine and alternative opioids in cancer pain: The EAPC recommendations. Br J Cancer. 2001;84:587-593.
    • (2001) Br J Cancer , vol.84 , pp. 587-593
    • Hanks, G.W.1    de Conno, F.2    Cherny, N.3
  • 14
    • 77949406284 scopus 로고    scopus 로고
    • Breakthrough pain in cancer patients: The need for evidence
    • Hui D, Bruera E. Breakthrough pain in cancer patients: The need for evidence. Eur J Palliat Care. 2010;17:58-67.
    • (2010) Eur J Palliat Care , vol.17 , pp. 58-67
    • Hui, D.1    Bruera, E.2
  • 15
    • 43049104583 scopus 로고    scopus 로고
    • Opioids for cancer breakthrough pain: A pilot study reporting patient assessment of time to meaningful pain relief
    • Zeppetella G. Opioids for cancer breakthrough pain: A pilot study reporting patient assessment of time to meaningful pain relief. J Pain Symptom Manage. 2008;35:563-567.
    • (2008) J Pain Symptom Manage , vol.35 , pp. 563-567
    • Zeppetella, G.1
  • 16
    • 1642619135 scopus 로고    scopus 로고
    • Safety and effectiveness of intravenous morphine for episodic (breakthrough) pain using a fixed ratio of with the oral daily morphine dose
    • Mercadante S, Villari P, Ferrera P, Bianchi M, Casuccio A. Safety and effectiveness of intravenous morphine for episodic (breakthrough) pain using a fixed ratio of with the oral daily morphine dose. J Pain Symptom Manage. 2004;27:352-359.
    • (2004) J Pain Symptom Manage , vol.27 , pp. 352-359
    • Mercadante, S.1    Villari, P.2    Ferrera, P.3    Bianchi, M.4    Casuccio, A.5
  • 17
    • 14044253370 scopus 로고    scopus 로고
    • The "pain pen" for breakthrough cancer pain: A promising treatment
    • Enting R, Mucchiano C, Oldenmenger WH, et al. The "pain pen" for breakthrough cancer pain: A promising treatment. J Pain Symptom Manage. 2005;29:213-217.
    • (2005) J Pain Symptom Manage , vol.29 , pp. 213-217
    • Enting, R.1    Mucchiano, C.2    Oldenmenger, W.H.3
  • 18
    • 0028935050 scopus 로고
    • Role of rectal route in treating cancer pain: A randomized crossover trial of oral versus rectal morphine administration in opioid-naive cancer patients with pain
    • de Conno, Ripamonti C, Saita L, et al. Role of rectal route in treating cancer pain: A randomized crossover trial of oral versus rectal morphine administration in opioid-naive cancer patients with pain. J Clin Oncol. 1995;13:1004-1008.
    • (1995) J Clin Oncol , vol.13 , pp. 1004-1008
    • de, C.1    Ripamonti, C.2    Saita, L.3
  • 19
    • 2542422772 scopus 로고    scopus 로고
    • Polyanalgesic consensus conference 2003: An update on the management of pain by intraspinal drug delivery - report of an expert panel
    • Hassenbusch SJ, Portenoy RK, Cousins M, et al. Polyanalgesic consensus conference 2003: An update on the management of pain by intraspinal drug delivery - report of an expert panel. J Pain Symptom Manage. 2004;27:540-563.
    • (2004) J Pain Symptom Manage , vol.27 , pp. 540-563
    • Hassenbusch, S.J.1    Portenoy, R.K.2    Cousins, M.3
  • 20
    • 40849092551 scopus 로고    scopus 로고
    • An observational study of oncology patients' utilisation of breakthrough pain medication
    • Davies AN, Vriens J, Kennett A, McTaggart M. An observational study of oncology patients' utilisation of breakthrough pain medication. J Pain Symptom Manage. 2008;35:406-411.
    • (2008) J Pain Symptom Manage , vol.35 , pp. 406-411
    • Davies, A.N.1    Vriens, J.2    Kennett, A.3    McTaggart, M.4
  • 23
    • 80051664822 scopus 로고    scopus 로고
    • The role of ketamine in the management of neuropathic cancer pain - a Polish experience
    • In: Wells CD, editor, Athens: Medimond International
    • Leppert W. The role of ketamine in the management of neuropathic cancer pain - a Polish experience. In: Wells CD, editor. Proceedings of the Third International Congress on Neuropathic Pain. Athens: Medimond International; 2010.
    • (2010) Proceedings of the Third International Congress on Neuropathic Pain
    • Leppert, W.1
  • 24
    • 28344436049 scopus 로고    scopus 로고
    • Alternative treatments of breakthrough pain in patients receiving spinal analgesics for pain
    • Mercadante S, Arcuri E, Ferrera P, Villari P, Mangione S. Alternative treatments of breakthrough pain in patients receiving spinal analgesics for pain. J Pain Symptom Manage. 2005;30:485-491.
    • (2005) J Pain Symptom Manage , vol.30 , pp. 485-491
    • Mercadante, S.1    Arcuri, E.2    Ferrera, P.3    Villari, P.4    Mangione, S.5
  • 25
    • 52149087667 scopus 로고    scopus 로고
    • Rola radioterapii w leczeniu objawow zaawansowanej choroby nowotworowej
    • Leppert W, Nowakowska E. Rola radioterapii w leczeniu objawow zaawansowanej choroby nowotworowej. Med Paliat Prakt. 2008;2: 33-47.
    • (2008) Med Paliat Prakt , vol.2 , pp. 33-47
    • Leppert, W.1    Nowakowska, E.2
  • 26
    • 22644437409 scopus 로고    scopus 로고
    • Percutaneous vertebroplasty - a technique to treat refractory spinal pain in the setting of advanced metastatic cancer: A case series
    • Burton AW, Reddy SK, Shah HN, Tremont-Lukats I, Mendel E. Percutaneous vertebroplasty - a technique to treat refractory spinal pain in the setting of advanced metastatic cancer: A case series. J Pain Symptom Manage. 2005;30:87-95.
    • (2005) J Pain Symptom Manage , vol.30 , pp. 87-95
    • Burton, A.W.1    Reddy, S.K.2    Shah, H.N.3    Tremont-Lukats, I.4    Mendel, E.5
  • 27
    • 0026631822 scopus 로고
    • Transdermal fentanyl in cancer pain
    • Moser KM. Transdermal fentanyl in cancer pain. Am Fam Phys. 1992; 45:2289-2294.
    • (1992) Am Fam Phys , vol.45 , pp. 2289-2294
    • Moser, K.M.1
  • 28
    • 70350093401 scopus 로고    scopus 로고
    • The role of fentanyl in cancer-related pain
    • Prommer E. The role of fentanyl in cancer-related pain. J Palliat Med. 2009;12:947-954.
    • (2009) J Palliat Med , vol.12 , pp. 947-954
    • Prommer, E.1
  • 29
    • 0030909704 scopus 로고    scopus 로고
    • Transdermal fentanyl versus sustained-release oral morphine in cancer pain: Preference, efficacy, and quality of life
    • Ahmedzai S, Brooks D. Transdermal fentanyl versus sustained-release oral morphine in cancer pain: Preference, efficacy, and quality of life. J Pain Symptom Manage. 1997;13:254-261.
    • (1997) J Pain Symptom Manage , vol.13 , pp. 254-261
    • Ahmedzai, S.1    Brooks, D.2
  • 31
    • 78049402475 scopus 로고    scopus 로고
    • Narkotyczne leki przeciwbolowe
    • In: Gumulka W, Meszaros J, editors, Warszawa: Osrodek Informacji Naukowej Polfa
    • Gumulka WS. Narkotyczne leki przeciwbolowe. In: Gumulka W, Meszaros J, editors. Wspolczesne Metody Zwalczania Bolu. Warszawa: Osrodek Informacji Naukowej Polfa; 2000.
    • (2000) Wspolczesne Metody Zwalczania Bolu
    • Gumulka, W.S.1
  • 32
    • 33747872664 scopus 로고    scopus 로고
    • Fentanyl may increase breathlessness in a patient with motor neuron disease
    • Zylicz Z, van Rijn-van der Plaat LL. Fentanyl may increase breathlessness in a patient with motor neuron disease. J Pain Symptom Manage. 2006;32:199-200.
    • (2006) J Pain Symptom Manage , vol.32 , pp. 199-200
    • Zylicz, Z.1    van Rijn-van der Plaat, L.L.2
  • 34
    • 43049099677 scopus 로고    scopus 로고
    • Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: An observational study
    • Gauna AA, Kang SK, Triano ML, Swatko ER, Vanston VJ. Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: An observational study. J Palliat Med. 2008;11:643-648.
    • (2008) J Palliat Med , vol.11 , pp. 643-648
    • Gauna, A.A.1    Kang, S.K.2    Triano, M.L.3    Swatko, E.R.4    Vanston, V.J.5
  • 35
    • 77949456685 scopus 로고    scopus 로고
    • Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care - overview and case report
    • German
    • Sitte T. Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care - overview and case report. Wien Med Wochenschr. 2009;159:566-570. German.
    • (2009) Wien Med Wochenschr , vol.159 , pp. 566-570
    • Sitte, T.1
  • 37
    • 0030774527 scopus 로고    scopus 로고
    • Fentanyl metabolism by human hepatic and intestinal cytochrome P4503A4: Implications for interindividual variability in disposition, efficacy, and drug interactions
    • Labroo RB, Paine MF, Thummel KE, Kharasch ED. Fentanyl metabolism by human hepatic and intestinal cytochrome P4503A4: Implications for interindividual variability in disposition, efficacy, and drug interactions. Drug Metab Dispos. 1997;25:1072-1080.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1072-1080
    • Labroo, R.B.1    Paine, M.F.2    Thummel, K.E.3    Kharasch, E.D.4
  • 38
    • 34548443321 scopus 로고    scopus 로고
    • The use of opioid analgesia in end-stage renal disease patients managed without dialysis: Recommendations for practice
    • Murtagh FE, Chai MO, Donohoe P, Edmonds PM, Higginson IJ. The use of opioid analgesia in end-stage renal disease patients managed without dialysis: Recommendations for practice. J Pain Palliat Care Pharmacother. 2007;21:5-16.
    • (2007) J Pain Palliat Care Pharmacother , vol.21 , pp. 5-16
    • Murtagh, F.E.1    Chai, M.O.2    Donohoe, P.3    Edmonds, P.M.4    Higginson, I.J.5
  • 39
    • 18444363020 scopus 로고    scopus 로고
    • Nasal administration of opioids for pain management in adults
    • Dale O, Hjortkjaer R, Kharasch ED. Nasal administration of opioids for pain management in adults. Acta Anaesthesiol Scand. 2002;46: 759-770.
    • (2002) Acta Anaesthesiol Scand , vol.46 , pp. 759-770
    • Dale, O.1    Hjortkjaer, R.2    Kharasch, E.D.3
  • 40
    • 78049404429 scopus 로고    scopus 로고
    • Bol przebijajacy w chorobie nowotworowej. Niedoceniany problem
    • Anonymous, Warszawa: Nycomed Pharma
    • Anonymous. Bol przebijajacy w chorobie nowotworowej. Niedoceniany problem. Nowa metoda leczenia. Instanyl - fentanyl aerozol donosowy. Warszawa: Nycomed Pharma; 2009.
    • (2009) Nowa metoda leczenia. Instanyl - fentanyl aerozol donosowy
  • 41
    • 52949120344 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery
    • Foster D, Upton R, Christrup L, et al. Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery. Ann Pharmacother. 2008;42:1380-1387.
    • (2008) Ann Pharmacother , vol.42 , pp. 1380-1387
    • Foster, D.1    Upton, R.2    Christrup, L.3
  • 42
    • 84890911322 scopus 로고    scopus 로고
    • Anonymous, NYCOMED. Available at:, Accessed 2010 Jul 9
    • Anonymous. Instanyl intranasal fentanyl spray. NYCOMED. Available at: www.instanyl.com. Accessed 2010 Jul 9.
    • Instanyl intranasal fentanyl spray
  • 45
    • 77951028134 scopus 로고    scopus 로고
    • Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer
    • Vissers D, Stam W, Nolte T, Lenre M, Jansen J. Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer. Curr Med Res Opin. 2010;26:1037-1045.
    • (2010) Curr Med Res Opin , vol.26 , pp. 1037-1045
    • Vissers, D.1    Stam, W.2    Nolte, T.3    Lenre, M.4    Jansen, J.5
  • 46
    • 0026723834 scopus 로고
    • Postoperative pain management by intranasal demand-adapted fentanyl titration
    • Striebel HW, Koenigs D, Krämer J. Postoperative pain management by intranasal demand-adapted fentanyl titration. Anesthesiology. 1992;77: 281-285.
    • (1992) Anesthesiology , vol.77 , pp. 281-285
    • Striebel, H.W.1    Koenigs, D.2    Krämer, J.3
  • 47
    • 0033759857 scopus 로고    scopus 로고
    • Patient-controlled intranasal analgesia: Effective alternative to intravenous PCA for postoperative pain relief
    • Toussaint S, Maidl J, Schwagmaier R, Striebel HW. Patient-controlled intranasal analgesia: Effective alternative to intravenous PCA for postoperative pain relief. Can J Anesth. 2000;47:299-302.
    • (2000) Can J Anesth , vol.47 , pp. 299-302
    • Toussaint, S.1    Maidl, J.2    Schwagmaier, R.3    Striebel, H.W.4
  • 48
    • 0033636498 scopus 로고    scopus 로고
    • Use of intranasal fentanyl in children undergoing myringotomy and tube placement during halothane and sevoflurane anesthesia
    • Galinkin JL, Fazi LM, Cuy RM, et al. Use of intranasal fentanyl in children undergoing myringotomy and tube placement during halothane and sevoflurane anesthesia. Anesthesiology. 2000;93:1378-1383.
    • (2000) Anesthesiology , vol.93 , pp. 1378-1383
    • Galinkin, J.L.1    Fazi, L.M.2    Cuy, R.M.3
  • 49
    • 0036190293 scopus 로고    scopus 로고
    • Intranasal fentanyl provides adequate postoperative analgesia in pediatric patients
    • Manjushree R, Lahiri A, Ghosh BR, Laha A, Handa K. Intranasal fentanyl provides adequate postoperative analgesia in pediatric patients. Can J Anesth. 2002;49:190-193.
    • (2002) Can J Anesth , vol.49 , pp. 190-193
    • Manjushree, R.1    Lahiri, A.2    Ghosh, B.R.3    Laha, A.4    Handa, K.5
  • 50
    • 0033954072 scopus 로고    scopus 로고
    • Nebulized and intranasal fentanyl in the management of cancer-related breakthrough pain
    • Zeppetella G. Nebulized and intranasal fentanyl in the management of cancer-related breakthrough pain. Palliat Med. 2000;14:57-58.
    • (2000) Palliat Med , vol.14 , pp. 57-58
    • Zeppetella, G.1
  • 51
    • 0033797308 scopus 로고    scopus 로고
    • An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: A pilot study
    • Zeppetella G. An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: A pilot study. J Pain Symptom Manage. 2000;20: 253-258.
    • (2000) J Pain Symptom Manage , vol.20 , pp. 253-258
    • Zeppetella, G.1
  • 52
    • 68949120909 scopus 로고    scopus 로고
    • Efficacy and tolerability of intranasal fentanyl spray 50 to 200 μg for breakthrough pain in patients with cancer: A Phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatment period
    • Kress HG, Oronska A, Kaczmarek Z, Kaasa S, Colberg T, Nolte T. Efficacy and tolerability of intranasal fentanyl spray 50 to 200 μg for breakthrough pain in patients with cancer: A Phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatment period. Clin Ther. 2009;31: 1177-1191.
    • (2009) Clin Ther , vol.31 , pp. 1177-1191
    • Kress, H.G.1    Oronska, A.2    Kaczmarek, Z.3    Kaasa, S.4    Colberg, T.5    Nolte, T.6
  • 53
    • 72549097280 scopus 로고    scopus 로고
    • A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: An open-label, randomised, crossover trial
    • Mercadante S, Radbruch L, Davies A, et al. A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: An open-label, randomised, crossover trial. Curr Med Res Opin. 2009;25:2805-2815.
    • (2009) Curr Med Res Opin , vol.25 , pp. 2805-2815
    • Mercadante, S.1    Radbruch, L.2    Davies, A.3
  • 54
    • 78049405361 scopus 로고    scopus 로고
    • An economic evaluation of fastacting opioids for the treatment of breakthrough pain in cancer patients in Sweden
    • Stam W, Vissers D, Lenre M, et al. An economic evaluation of fastacting opioids for the treatment of breakthrough pain in cancer patients in Sweden. Eur J Pain. 2009;13 Suppl 1:S241.
    • (2009) Eur J Pain , vol.13 , Issue.SUPPL. 1
    • Stam, W.1    Vissers, D.2    Lenre, M.3
  • 55
    • 77949357470 scopus 로고    scopus 로고
    • The role of rapid-onset fentanyl in clinical practice
    • Burkey A, Ballantyne J. The role of rapid-onset fentanyl in clinical practice. Eur J Palliat Care. 2010;17:88-90.
    • (2010) Eur J Palliat Care , vol.17 , pp. 88-90
    • Burkey, A.1    Ballantyne, J.2
  • 56
    • 10744219957 scopus 로고    scopus 로고
    • Safety and efficacy of intranasal ketamine for the treatment of breakthrough pain in patients with chronic pain: A randomized, double-blind, placebo-controlled, crossover study
    • Carr DB, Goudas IC, Denman WT, et al. Safety and efficacy of intranasal ketamine for the treatment of breakthrough pain in patients with chronic pain: A randomized, double-blind, placebo-controlled, crossover study. Pain. 2004;108:17-27.
    • (2004) Pain , vol.108 , pp. 17-27
    • Carr, D.B.1    Goudas, I.C.2    Denman, W.T.3


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