The "pain pen" for breakthrough cancer pain: A promising treatment

Journal of Pain and Symptom Management

Volumn 29, Issue 2, 2005, Pages 213-217

  Enting, Roelien H ^a,d   Mucchiano, Carlo ^c   Oldenmenger, Wendy H ^a   Fritzon, Magdalena ^c   Wallen, Anna ^c   Goslinga Van Der Gaag, Simone ^b   Sillevis Smitt, Peter A E ^a   Delhaas, Elmar ^b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Medisch Centrum Rijnmond Zuid   (Netherlands)

^c Hogland Hospital   (Sweden)

^d Department of Neurology ^*  (Netherlands)

Author keywords

Breakthrough pain; Cancer; Injection pen; Opioids; Parenteral opioids; Rescue doses

Indexed keywords

ANALGESIC AGENT; FENTANYL; HYDROMORPHONE; KETOBEMIDONE; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; OXYCODONE; SUFENTANIL;

ADULT; ARTICLE; CANCER PAIN; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; DRUG EFFICACY; DRUG SELF ADMINISTRATION; HUMAN; INJECTION; INSTRUMENTATION; MAJOR CLINICAL STUDY; MEDICAL INSTRUMENTATION; PILOT STUDY; RATING SCALE; SIDE EFFECT;

EID: 14044253370     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2004.05.010     Document Type: Article

References (19)

1. World Health Organization Cancer pain relief and palliative care. Report of a WHO expert committee 1990 World Health Organization Geneva
2. S. Mercadante, L. Radbruch, and A. Caraceni Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care Cancer 94 2002 832 839
3. G.W. Hanks, F. de Conno, and N. Cherny Morphine and alternative opioids in cancer pain: the EAPC recommendations Br J Cancer 84 2001 587 593
4. Delhaas E, Savage C, Sillevis Smitt P, et al. Preliminary results of the pain pen: a "breakthrough" for breakthrough pain? [Abstract] Proceedings of the 7th Congress of the European Association for Palliative Care. Palermo, Italy, 2001.
5. Mucchiano C, Fritzon M, Wallen A. Self-administration of SC hydromorphone with D-pen for breakthrough pain during opioid medication with Duragesic patch. [Abstract] Proceedings of the 7th Congress of the European Association for Palliative Care. Palermo, Italy, 2001.
6. R.K. Portenoy, and P. Lesage Management of cancer pain Lancet 353 1999 1695 1700
7. W. Breitbart, S. Chandler, and B. Eagel An alternative algorithm for dosing transdermal fentanyl for cancer-related pain Oncology 14 2000 695 717
8. R.K. Portenoy, and N.A. Hagen Breakthrough pain: definition, prevalence and characteristics Pain 41 1990 273 281
9. R.K. Portenoy, R. Payne, and P. Jacobsen Breakthrough pain: characteristics and impact in patients with cancer pain Pain 81 1999 129 134
10. X. Gomez-Batiste, F. Madrid, and F. Moreno Breakthrough cancer pain: Prevalence and characteristics in patients in Catalonia, Spain J Pain Symptom Manage 24 2002 45 52
11. P.H. Coluzzi, L. Schwartzberg, and J.D. Conroy Breakthrough cancer pain: A randomized trial comparing oral transmucosal fentanyl citrate (OTFC) and morphine sulfate immediate release (MSIR) Pain 91 2001 123 130
12. G. Zeppetella An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: A pilot study J Pain Symptom Manage 20 2000 253 258
13. K.M. Kunz, J.A. Theisen, and M.E. Schroeder Severe episodic pain: Management with sublingual sufentanil J Pain Symptom Manage 9 1993 189 190
14. G. Zeppetella Sublingual fentanyl citrate for cancer-related breakthrough pain: A pilot study Palliat Med 15 2001 323 328
15. K. Jackson, M. Ashby, and J. Keech Pilot dose finding study of intranasal sufentanil for breakthrough and incident cancer-associated pain J Pain Symptom Manage 23 2002 450 452
16. J.L. Lichtor, F.B. Sevarino, and G.P. Joshi The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain Anesth Analg 89 1999 732 738
17. Caraceni A, Brunelli C, Galbiati A, et al. Role and limits of morphine PCA infusions for the treatment of breakthrough pain in cancer: Preliminary results. [Abstract] Proceedings of the 7th Congress of the European Association for Palliative Care. Palermo, Italy, 2001.
18. G. Walker, A. Wilcock, and C. Manderson The acceptability of different routes of administration of analgesia for breakthrough pain Palliat Med 17 2003 219 221
19. P.J. Roos, J.H. Glerum, and J.H. Meilink Stability of sufentanil citrate in a portable pump reservoir, a glass container, and a polyethylene container Pharm Weekly Sci 14 1992 196 200