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Volumn 32, Issue 1, 2008, Pages 70-80

Dif1 Is a DNA-Damage-Regulated Facilitator of Nuclear Import for Ribonucleotide Reductase

Author keywords

CELLBIO; DNA; SIGNALING

Indexed keywords

DAMAGE REGULATED IMPORT FACILITATOR 1; DUN1 PROTEIN; FUNGAL PROTEIN; MEC1 PROTEIN; MEDIATED CHECKPOINT RESPONSE 1; REGULATOR PROTEIN; RIBONUCLEOTIDE DIPHOSPHATE 2; RIBONUCLEOTIDE DIPHOSPHATE 4; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG; WTM1 PROTEIN;

EID: 53349151829     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2008.08.018     Document Type: Article
Times cited : (96)

References (34)
  • 1
    • 0032826786 scopus 로고    scopus 로고
    • NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae
    • Basrai M.A., Velculescu V.E., Kinzler K.W., and Hieter P. NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol. Cell. Biol. 19 (1999) 7041-7049
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7041-7049
    • Basrai, M.A.1    Velculescu, V.E.2    Kinzler, K.W.3    Hieter, P.4
  • 2
    • 0033579443 scopus 로고    scopus 로고
    • Yeast Sml1, a protein inhibitor of ribonucleotide reductase
    • Chabes A., Domkin V., and Thelander L. Yeast Sml1, a protein inhibitor of ribonucleotide reductase. J. Biol. Chem. 274 (1999) 36679-36683
    • (1999) J. Biol. Chem. , vol.274 , pp. 36679-36683
    • Chabes, A.1    Domkin, V.2    Thelander, L.3
  • 3
    • 0037423223 scopus 로고    scopus 로고
    • Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase
    • Chabes A., Georgieva B., Domkin V., Zhao X., Rothstein R., and Thelander L. Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase. Cell 112 (2003) 391-401
    • (2003) Cell , vol.112 , pp. 391-401
    • Chabes, A.1    Georgieva, B.2    Domkin, V.3    Zhao, X.4    Rothstein, R.5    Thelander, L.6
  • 4
    • 0032530824 scopus 로고    scopus 로고
    • Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
    • Desany B.A., Alcasabas A.A., Bachant J.B., and Elledge S.J. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev. 12 (1998) 2956-2970
    • (1998) Genes Dev. , vol.12 , pp. 2956-2970
    • Desany, B.A.1    Alcasabas, A.A.2    Bachant, J.B.3    Elledge, S.J.4
  • 6
    • 0035964255 scopus 로고    scopus 로고
    • Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4
    • Ge J., Perlstein D.L., Nguyen H.H., Bar G., Griffin R.G., and Stubbe J. Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4. Proc. Natl. Acad. Sci. USA 98 (2001) 10067-10072
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10067-10072
    • Ge, J.1    Perlstein, D.L.2    Nguyen, H.H.3    Bar, G.4    Griffin, R.G.5    Stubbe, J.6
  • 7
    • 33644972445 scopus 로고    scopus 로고
    • The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit
    • Hakansson P., Dahl L., Chilkova O., Domkin V., and Thelander L. The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit. J. Biol. Chem. 281 (2006) 1778-1783
    • (2006) J. Biol. Chem. , vol.281 , pp. 1778-1783
    • Hakansson, P.1    Dahl, L.2    Chilkova, O.3    Domkin, V.4    Thelander, L.5
  • 8
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper J.W., and Elledge S.J. The DNA damage response: ten years after. Mol. Cell 28 (2007) 739-745
    • (2007) Mol. Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 10
    • 0032483576 scopus 로고    scopus 로고
    • The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
    • Huang M., Zhou Z., and Elledge S.J. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell 94 (1998) 595-605
    • (1998) Cell , vol.94 , pp. 595-605
    • Huang, M.1    Zhou, Z.2    Elledge, S.J.3
  • 11
    • 1942452749 scopus 로고    scopus 로고
    • Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae
    • Kellis M., Birren B.W., and Lander E.S. Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae. Nature 428 (2004) 617-624
    • (2004) Nature , vol.428 , pp. 617-624
    • Kellis, M.1    Birren, B.W.2    Lander, E.S.3
  • 13
    • 32044442056 scopus 로고    scopus 로고
    • Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1
    • Lee Y.D., and Elledge S.J. Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1. Genes Dev. 20 (2006) 334-344
    • (2006) Genes Dev. , vol.20 , pp. 334-344
    • Lee, Y.D.1    Elledge, S.J.2
  • 14
    • 2542610684 scopus 로고    scopus 로고
    • UV-C response of the ribonucleotide reductase large subunit involves both E2F-mediated gene transcriptional regulation and protein subcellular relocalization in tobacco cells
    • Lincker F., Philipps G., and Chaboute M.E. UV-C response of the ribonucleotide reductase large subunit involves both E2F-mediated gene transcriptional regulation and protein subcellular relocalization in tobacco cells. Nucleic Acids Res. 32 (2004) 1430-1438
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1430-1438
    • Lincker, F.1    Philipps, G.2    Chaboute, M.E.3
  • 15
    • 0038185375 scopus 로고    scopus 로고
    • Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms
    • Liu C., Powell K.A., Mundt K., Wu L., Carr A.M., and Caspari T. Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes Dev. 17 (2003) 1130-1140
    • (2003) Genes Dev. , vol.17 , pp. 1130-1140
    • Liu, C.1    Powell, K.A.2    Mundt, K.3    Wu, L.4    Carr, A.M.5    Caspari, T.6
  • 16
  • 17
    • 0030804309 scopus 로고    scopus 로고
    • The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
    • Longhese M.P., Paciotti V., Fraschini R., Zaccarini R., Plevani P., and Lucchini G. The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J. 16 (1997) 5216-5226
    • (1997) EMBO J. , vol.16 , pp. 5216-5226
    • Longhese, M.P.1    Paciotti, V.2    Fraschini, R.3    Zaccarini, R.4    Plevani, P.5    Lucchini, G.6
  • 18
    • 0033168194 scopus 로고    scopus 로고
    • The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae
    • Neville M., and Rosbash M. The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae. EMBO J. 18 (1999) 3746-3756
    • (1999) EMBO J. , vol.18 , pp. 3746-3756
    • Neville, M.1    Rosbash, M.2
  • 19
    • 0033607284 scopus 로고    scopus 로고
    • Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly
    • Nguyen H.H., Ge J., Perlstein D.L., and Stubbe J. Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly. Proc. Natl. Acad. Sci. USA 96 (1999) 12339-12344
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12339-12344
    • Nguyen, H.H.1    Ge, J.2    Perlstein, D.L.3    Stubbe, J.4
  • 21
    • 0037082119 scopus 로고    scopus 로고
    • Ribonucleotide reductases: the evolution of allosteric regulation
    • Reichard P. Ribonucleotide reductases: the evolution of allosteric regulation. Arch. Biochem. Biophys. 397 (2002) 149-155
    • (2002) Arch. Biochem. Biophys. , vol.397 , pp. 149-155
    • Reichard, P.1
  • 23
    • 1642442486 scopus 로고    scopus 로고
    • Identification of phosphorylation sites on the yeast ribonucleotide reductase inhibitor Sml1
    • Uchiki T., Dice L.T., Hettich R.L., and Dealwis C. Identification of phosphorylation sites on the yeast ribonucleotide reductase inhibitor Sml1. J. Biol. Chem. 279 (2004) 11293-11303
    • (2004) J. Biol. Chem. , vol.279 , pp. 11293-11303
    • Uchiki, T.1    Dice, L.T.2    Hettich, R.L.3    Dealwis, C.4
  • 24
    • 0032956282 scopus 로고    scopus 로고
    • Interaction between the MEC1-dependent DNA synthesis checkpoint and G1 cyclin function in Saccharomyces cerevisiae
    • Vallen E.A., and Cross F.R. Interaction between the MEC1-dependent DNA synthesis checkpoint and G1 cyclin function in Saccharomyces cerevisiae. Genetics 151 (1999) 459-471
    • (1999) Genetics , vol.151 , pp. 459-471
    • Vallen, E.A.1    Cross, F.R.2
  • 25
    • 0032189952 scopus 로고    scopus 로고
    • The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
    • Vialard J.E., Gilbert C.S., Green C.M., and Lowndes N.F. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J. 17 (1998) 5679-5688
    • (1998) EMBO J. , vol.17 , pp. 5679-5688
    • Vialard, J.E.1    Gilbert, C.S.2    Green, C.M.3    Lowndes, N.F.4
  • 27
    • 0037374051 scopus 로고    scopus 로고
    • Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits
    • Xue L., Zhou B., Liu X., Qiu W., Jin Z., and Yen Y. Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits. Cancer Res. 63 (2003) 980-986
    • (2003) Cancer Res. , vol.63 , pp. 980-986
    • Xue, L.1    Zhou, B.2    Liu, X.3    Qiu, W.4    Jin, Z.5    Yen, Y.6
  • 28
    • 0038312250 scopus 로고    scopus 로고
    • Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways
    • Yao R., Zhang Z., An X., Bucci B., Perlstein D.L., Stubbe J., and Huang M. Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways. Proc. Natl. Acad. Sci. USA 100 (2003) 6628-6633
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6628-6633
    • Yao, R.1    Zhang, Z.2    An, X.3    Bucci, B.4    Perlstein, D.L.5    Stubbe, J.6    Huang, M.7
  • 29
    • 31944444142 scopus 로고    scopus 로고
    • Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein
    • Zhang Z., An X., Yang K., Perlstein D.L., Hicks L., Kelleher N., Stubbe J., and Huang M. Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein. Proc. Natl. Acad. Sci. USA 103 (2006) 1422-1427
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1422-1427
    • Zhang, Z.1    An, X.2    Yang, K.3    Perlstein, D.L.4    Hicks, L.5    Kelleher, N.6    Stubbe, J.7    Huang, M.8
  • 30
    • 33847779064 scopus 로고    scopus 로고
    • Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1
    • Zhang Z., Yang K., Chen C.C., Feser J., and Huang M. Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1. Proc. Natl. Acad. Sci. USA 104 (2007) 2217-2222
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2217-2222
    • Zhang, Z.1    Yang, K.2    Chen, C.C.3    Feser, J.4    Huang, M.5
  • 31
    • 0037133566 scopus 로고    scopus 로고
    • The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1
    • Zhao X., and Rothstein R. The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc. Natl. Acad. Sci. USA 99 (2002) 3746-3751
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3746-3751
    • Zhao, X.1    Rothstein, R.2
  • 32
    • 0032161269 scopus 로고    scopus 로고
    • A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools
    • Zhao X., Muller E.G., and Rothstein R. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools. Mol. Cell 2 (1998) 329-340
    • (1998) Mol. Cell , vol.2 , pp. 329-340
    • Zhao, X.1    Muller, E.G.2    Rothstein, R.3
  • 33
    • 0034460153 scopus 로고    scopus 로고
    • Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality
    • Zhao X., Georgieva B., Chabes A., Domkin V., Ippel J.H., Schleucher J., Wijmenga S., Thelander L., and Rothstein R. Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality. Mol. Cell. Biol. 20 (2000) 9076-9083
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 9076-9083
    • Zhao, X.1    Georgieva, B.2    Chabes, A.3    Domkin, V.4    Ippel, J.H.5    Schleucher, J.6    Wijmenga, S.7    Thelander, L.8    Rothstein, R.9
  • 34
    • 0026651652 scopus 로고
    • Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae
    • Zhou Z., and Elledge S.J. Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics 131 (1992) 851-866
    • (1992) Genetics , vol.131 , pp. 851-866
    • Zhou, Z.1    Elledge, S.J.2


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