Active site conformational dynamics in human uridine phosphorylase 1

PLoS ONE

Volumn 5, Issue 9, 2010, Pages 1-6

  Roosild, Tarmo P ^a   Castronovo, Samantha ^a  

^a NEVADA CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; PHOSPHORYLASE; UNCLASSIFIED DRUG; URIDINE PHOSPHORYLASE 1; URIDINE; URIDINE PHOSPHORYLASE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLIZATION; DRUG DESIGN; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; LIGAND BINDING; PROTEIN TARGETING; STRUCTURE ANALYSIS; BIOCATALYSIS; CHEMISTRY; CONFORMATION; DIMERIZATION; ENZYME SPECIFICITY; GENETICS; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; FLUOROURACIL; HUMANS; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; URIDINE; URIDINE PHOSPHORYLASE;

EID: 77958616332     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012741     Document Type: Article

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