메뉴 건너뛰기




Volumn 5, Issue 9, 2010, Pages 1-9

Inhibition of melanoma growth by subcutaneous administration of hTERTC27 viral cocktail in C57BL/6 mice

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GANGLIOSIDE GM1 ANTIBODY; PARVOVIRUS VECTOR; TELOMERASE REVERSE TRANSCRIPTASE; CANCER VACCINE; TELOMERASE; TERT PROTEIN, HUMAN;

EID: 77958583393     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012705     Document Type: Article
Times cited : (11)

References (57)
  • 1
    • 67651241055 scopus 로고    scopus 로고
    • Cutaneous melanoma in the era of molecular profiling
    • Thompson JF, Scolyer RA, Kefford RF (2009) Cutaneous melanoma in the era of molecular profiling. Lancet 374: 362-365.
    • (2009) Lancet , vol.374 , pp. 362-365
    • Thompson, J.F.1    Scolyer, R.A.2    Kefford, R.F.3
  • 2
    • 0037333374 scopus 로고    scopus 로고
    • Malignant melanoma: Current state of primary and adjuvant treatment
    • Pawlik TM, Sondak VK (2003) Malignant melanoma: current state of primary and adjuvant treatment. Crit Rev Oncol Hematol 45: 245-264.
    • (2003) Crit Rev Oncol Hematol , vol.45 , pp. 245-264
    • Pawlik, T.M.1    Sondak, V.K.2
  • 3
    • 3843113670 scopus 로고    scopus 로고
    • Re-evaluating the role of dacarbazine in metastatic melanoma: What have we learned in 30 years?
    • Eggermont AM, Kirkwood JM (2004) Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years? Eur J Cancer 40: 1825-1836.
    • (2004) Eur J Cancer , vol.40 , pp. 1825-1836
    • Eggermont, A.M.1    Kirkwood, J.M.2
  • 5
    • 0035397975 scopus 로고    scopus 로고
    • Outpatient biochemotherapy with interleukin-2 and interferon alfa-2b in patients with metastatic malignant melanoma: Results of two phase II cytokine working group trials
    • Flaherty LE, Atkins M, Sosman J, Weiss G, Clark JI, et al. (2001) Outpatient biochemotherapy with interleukin-2 and interferon alfa-2b in patients with metastatic malignant melanoma: results of two phase II cytokine working group trials. J Clin Oncol 19: 3194-3202.
    • (2001) J Clin Oncol , vol.19 , pp. 3194-3202
    • Flaherty, L.E.1    Atkins, M.2    Sosman, J.3    Weiss, G.4    Clark, J.I.5
  • 6
    • 0035136793 scopus 로고    scopus 로고
    • Single-agent DTIC versus combination chemotherapy with or without immunotherapy in metastatic melanoma: A meta-analysis of 3273 patients from 20 randomized trials
    • Huncharek M, Caubet JF, McGarry R (2001) Single-agent DTIC versus combination chemotherapy with or without immunotherapy in metastatic melanoma: a meta-analysis of 3273 patients from 20 randomized trials. Melanoma Res 11: 75-81.
    • (2001) Melanoma Res , vol.11 , pp. 75-81
    • Huncharek, M.1    Caubet, J.F.2    McGarry, R.3
  • 7
    • 33645092920 scopus 로고    scopus 로고
    • Cutaneous melanoma: Available therapy for metastatic disease
    • Tarhini AA, Agarwala SS (2006) Cutaneous melanoma: available therapy for metastatic disease. Dermatol Ther 19: 19-25.
    • (2006) Dermatol Ther , vol.19 , pp. 19-25
    • Tarhini, A.A.1    Agarwala, S.S.2
  • 8
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • Tsao H, Atkins MB, Sober AJ (2004) Management of cutaneous melanoma. N Engl J Med 351: 998-1012.
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 11
    • 27644458112 scopus 로고    scopus 로고
    • Biochemotherapy in metastatic melanoma: Quo vadis?
    • Queirolo P, Acquati M (2005) Biochemotherapy in metastatic melanoma: quo vadis? Melanoma Res 15: 471-473.
    • (2005) Melanoma Res , vol.15 , pp. 471-473
    • Queirolo, P.1    Acquati, M.2
  • 12
    • 53749087081 scopus 로고    scopus 로고
    • Anti-CTLA4 monoclonal antibody Ipilimumab in the treatment of metastatic melanoma: Recent findings
    • Lens M, Ferrucci PF, Testori A (2008) Anti-CTLA4 monoclonal antibody Ipilimumab in the treatment of metastatic melanoma: recent findings. Recent Pat Anticancer Drug Discov 3: 105-113.
    • (2008) Recent Pat Anticancer Drug Discov , vol.3 , pp. 105-113
    • Lens, M.1    Ferrucci, P.F.2    Testori, A.3
  • 13
    • 58149097697 scopus 로고    scopus 로고
    • Anti- CTLA4 monoclonal antibody induced sarcoidosis in a metastatic melanoma patient
    • Eckert A, Schoeffler A, Dalle S, Phan A, Kiakouama L, et al. (2009) Anti- CTLA4 monoclonal antibody induced sarcoidosis in a metastatic melanoma patient. Dermatology 218: 69-70.
    • (2009) Dermatology , vol.218 , pp. 69-70
    • Eckert, A.1    Schoeffler, A.2    Dalle, S.3    Phan, A.4    Kiakouama, L.5
  • 14
    • 67650491041 scopus 로고    scopus 로고
    • Anti-CTLA4 antibody-induced lupus nephritis
    • Fadel F, El Karoui K, Knebelmann B (2009) Anti-CTLA4 antibody-induced lupus nephritis. N Engl J Med 361: 211-212.
    • (2009) N Engl J Med , vol.361 , pp. 211-212
    • Fadel, F.1    El Karoui, K.2    Knebelmann, B.3
  • 18
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP (2004) Cancer immunotherapy: moving beyond current vaccines. Nat Med 10: 909-915.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 19
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, et al. (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3    Harley, C.B.4    West, M.D.5
  • 20
    • 34247115962 scopus 로고    scopus 로고
    • Telomeres and telomerase as targets for cancer therapy
    • Zimmermann S, Martens UM (2007) Telomeres and telomerase as targets for cancer therapy. Cell Mol Life Sci 64: 906-921.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 906-921
    • Zimmermann, S.1    Martens, U.M.2
  • 21
    • 0030923688 scopus 로고    scopus 로고
    • Clinical implications of telomerase in cancer
    • Kim NW (1997) Clinical implications of telomerase in cancer. Eur J Cancer 33: 781-786.
    • (1997) Eur J Cancer , vol.33 , pp. 781-786
    • Kim, N.W.1
  • 25
    • 0033151591 scopus 로고    scopus 로고
    • The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes
    • Vonderheide RH, Hahn WC, Schultze JL, Nadler LM (1999) The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 10: 673-679.
    • (1999) Immunity , vol.10 , pp. 673-679
    • Vonderheide, R.H.1    Hahn, W.C.2    Schultze, J.L.3    Nadler, L.M.4
  • 26
    • 0036606586 scopus 로고    scopus 로고
    • Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells
    • Huang JJ, Lin MC, Bai YX, Jing DD, Wong BC, et al. (2002) Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells. Cancer Res 62: 3226-3232.
    • (2002) Cancer Res , vol.62 , pp. 3226-3232
    • Huang, J.J.1    Lin, M.C.2    Bai, Y.X.3    Jing, D.D.4    Wong, B.C.5
  • 27
    • 34249027012 scopus 로고    scopus 로고
    • A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide
    • Ng SS, Gao Y, Chau DH, Li GH, Lai LH, et al. (2007) A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide. Cancer Gene Ther 14: 561-572.
    • (2007) Cancer Gene Ther , vol.14 , pp. 561-572
    • Ng, S.S.1    Gao, Y.2    Chau, D.H.3    Li, G.H.4    Lai, L.H.5
  • 28
    • 0029923638 scopus 로고    scopus 로고
    • Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
    • Ferrari FK, Samulski T, Shenk T, Samulski RJ (1996) Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol 70: 3227-3234.
    • (1996) J Virol , vol.70 , pp. 3227-3234
    • Ferrari, F.K.1    Samulski, T.2    Shenk, T.3    Samulski, R.J.4
  • 29
    • 1842740302 scopus 로고    scopus 로고
    • Combination of adeno-associated virus and adenovirus vectors expressing bone morphogenetic protein-2 produces enhanced osteogenic activity in immunocompetent rats
    • Chen Y, Luk KD, Cheung KM, Lu WW, An XM, et al. (2004) Combination of adeno-associated virus and adenovirus vectors expressing bone morphogenetic protein-2 produces enhanced osteogenic activity in immunocompetent rats. Biochem Biophys Res Commun 317: 675-681.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 675-681
    • Chen, Y.1    Luk, K.D.2    Cheung, K.M.3    Lu, W.W.4    An, X.M.5
  • 30
    • 53549088873 scopus 로고    scopus 로고
    • Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy
    • Gao Y, Ng SS, Chau DH, Yao H, Yang C, et al. (2008) Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy. Cancer Gene Ther 15: 723-732.
    • (2008) Cancer Gene Ther , vol.15 , pp. 723-732
    • Gao, Y.1    Ng, S.S.2    Chau, D.H.3    Yao, H.4    Yang, C.5
  • 31
    • 39449092745 scopus 로고    scopus 로고
    • Targeting telomerase for cancer therapeutics
    • Shay JW, Keith WN (2008) Targeting telomerase for cancer therapeutics. Br J Cancer 98: 677-683.
    • (2008) Br J Cancer , vol.98 , pp. 677-683
    • Shay, J.W.1    Keith, W.N.2
  • 32
    • 53549114206 scopus 로고    scopus 로고
    • NK cells and cancer immunosurveillance
    • Waldhauer I, Steinle A (2008) NK cells and cancer immunosurveillance. Oncogene 27: 5932-5943.
    • (2008) Oncogene , vol.27 , pp. 5932-5943
    • Waldhauer, I.1    Steinle, A.2
  • 33
    • 33750019822 scopus 로고    scopus 로고
    • During acute Trypanosoma cruzi infection highly susceptible mice deficient in natural killer cells are protected by a single alphagalactosylceramide treatment
    • Duthie MS, Kahn SJ (2006) During acute Trypanosoma cruzi infection highly susceptible mice deficient in natural killer cells are protected by a single alphagalactosylceramide treatment. Immunology 119: 355-361.
    • (2006) Immunology , vol.119 , pp. 355-361
    • Duthie, M.S.1    Kahn, S.J.2
  • 34
    • 0024253490 scopus 로고
    • Role of T helper/inducer cells as well as natural killer cells in resistance to Trypanosoma cruzi infection
    • Rottenberg M, Cardoni RL, Andersson R, Segura EL, Orn A (1988) Role of T helper/inducer cells as well as natural killer cells in resistance to Trypanosoma cruzi infection. Scand J Immunol 28: 573-582.
    • (1988) Scand J Immunol , vol.28 , pp. 573-582
    • Rottenberg, M.1    Cardoni, R.L.2    Andersson, R.3    Segura, E.L.4    Orn, A.5
  • 35
    • 0033837704 scopus 로고    scopus 로고
    • CD4(+) v(alpha)14 NKT cells play a crucial role in an early stage of protective immunity against infection with Leishmania major
    • Ishikawa H, Hisaeda H, Taniguchi M, Nakayama T, Sakai T, et al. (2000) CD4(+) v(alpha)14 NKT cells play a crucial role in an early stage of protective immunity against infection with Leishmania major. Int Immunol 12: 1267-1274.
    • (2000) Int Immunol , vol.12 , pp. 1267-1274
    • Ishikawa, H.1    Hisaeda, H.2    Taniguchi, M.3    Nakayama, T.4    Sakai, T.5
  • 36
    • 2142764513 scopus 로고    scopus 로고
    • IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners
    • Sun R, Tian Z, Kulkarni S, Gao B (2004) IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners. J Immunol 172: 5648-5655.
    • (2004) J Immunol , vol.172 , pp. 5648-5655
    • Sun, R.1    Tian, Z.2    Kulkarni, S.3    Gao, B.4
  • 37
    • 22344451592 scopus 로고    scopus 로고
    • Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
    • Smyth MJ, Wallace ME, Nutt SL, Yagita H, Godfrey DI, et al. (2005) Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer. J Exp Med 201: 1973-1985.
    • (2005) J Exp Med , vol.201 , pp. 1973-1985
    • Smyth, M.J.1    Wallace, M.E.2    Nutt, S.L.3    Yagita, H.4    Godfrey, D.I.5
  • 38
    • 0036604430 scopus 로고    scopus 로고
    • HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy
    • Scardino A, Gross DA, Alves P, Schultze JL, Graff-Dubois S, et al. (2002) HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol 168: 5900-5906.
    • (2002) J Immunol , vol.168 , pp. 5900-5906
    • Scardino, A.1    Gross, D.A.2    Alves, P.3    Schultze, J.L.4    Graff-Dubois, S.5
  • 39
    • 0035176221 scopus 로고    scopus 로고
    • Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase
    • Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, et al. (2001) Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin Cancer Res 7: 3343-3348.
    • (2001) Clin Cancer Res , vol.7 , pp. 3343-3348
    • Vonderheide, R.H.1    Anderson, K.S.2    Hahn, W.C.3    Butler, M.O.4    Schultze, J.L.5
  • 40
    • 0033826798 scopus 로고    scopus 로고
    • Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells
    • Nair SK, Heiser A, Boczkowski D, Majumdar A, Naoe M, et al. (2000) Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. Nat Med 6: 1011-1017.
    • (2000) Nat Med , vol.6 , pp. 1011-1017
    • Nair, S.K.1    Heiser, A.2    Boczkowski, D.3    Majumdar, A.4    Naoe, M.5
  • 41
    • 0036569585 scopus 로고    scopus 로고
    • Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells
    • Schroers R, Huang XF, Hammer J, Zhang J, Chen SY (2002) Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells. Cancer Res 62: 2600-2605.
    • (2002) Cancer Res , vol.62 , pp. 2600-2605
    • Schroers, R.1    Huang, X.F.2    Hammer, J.3    Zhang, J.4    Chen, S.Y.5
  • 42
    • 0142157136 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes
    • Schroers R, Shen L, Rollins L, Rooney CM, Slawin K, et al. (2003) Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes. Clin Cancer Res 9: 4743-4755.
    • (2003) Clin Cancer Res , vol.9 , pp. 4743-4755
    • Schroers, R.1    Shen, L.2    Rollins, L.3    Rooney, C.M.4    Slawin, K.5
  • 43
    • 0032977833 scopus 로고    scopus 로고
    • Induction of immunity to antigens expressed by recombinant adenoassociated virus depends on the route of administration
    • Brockstedt DG, Podsakoff GM, Fong L, Kurtzman G, Mueller-Ruchholtz W, et al. (1999) Induction of immunity to antigens expressed by recombinant adenoassociated virus depends on the route of administration. Clin Immunol 92: 67-75.
    • (1999) Clin Immunol , vol.92 , pp. 67-75
    • Brockstedt, D.G.1    Podsakoff, G.M.2    Fong, L.3    Kurtzman, G.4    Mueller-Ruchholtz, W.5
  • 44
    • 0043245914 scopus 로고    scopus 로고
    • Synergy between tumor immunotherapy and antiangiogenic therapy
    • Nair S, Boczkowski D, Moeller B, Dewhirst M, Vieweg J, et al. (2003) Synergy between tumor immunotherapy and antiangiogenic therapy. Blood 102: 964-971.
    • (2003) Blood , vol.102 , pp. 964-971
    • Nair, S.1    Boczkowski, D.2    Moeller, B.3    Dewhirst, M.4    Vieweg, J.5
  • 45
    • 0038235904 scopus 로고    scopus 로고
    • Cytokine-induced killer cells: NK-like T cells with cytotolytic specificity against leukemia
    • Linn YC, Hui KM (2003) Cytokine-induced killer cells: NK-like T cells with cytotolytic specificity against leukemia. Leuk Lymphoma 44: 1457-1462.
    • (2003) Leuk Lymphoma , vol.44 , pp. 1457-1462
    • Linn, Y.C.1    Hui, K.M.2
  • 46
    • 0036144194 scopus 로고    scopus 로고
    • IL-17: Prototype member of an emerging cytokine family
    • Aggarwal S, Gurney AL (2002) IL-17: prototype member of an emerging cytokine family. J Leukoc Biol 71: 1-8.
    • (2002) J Leukoc Biol , vol.71 , pp. 1-8
    • Aggarwal, S.1    Gurney, A.L.2
  • 47
    • 20344404231 scopus 로고    scopus 로고
    • Natural killer cells play a role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro
    • Kijima M, Saio M, Oyang GF, Suwa T, Miyauchi R, et al. (2005) Natural killer cells play a role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro. Int J Oncol 26: 679-684.
    • (2005) Int J Oncol , vol.26 , pp. 679-684
    • Kijima, M.1    Saio, M.2    Oyang, G.F.3    Suwa, T.4    Miyauchi, R.5
  • 48
    • 85026148406 scopus 로고    scopus 로고
    • Booster effect of interleukin-2 on natural killer 1.1+ cells stimulated by administration of macrophage colony-stimulating factor in mice
    • Misawa E, Sakurai T, Yamada M, Hayasawa H, Motoyoshi K (2003) Booster effect of interleukin-2 on natural killer 1.1+ cells stimulated by administration of macrophage colony-stimulating factor in mice. J Immunother 26: 21-30.
    • (2003) J Immunother , vol.26 , pp. 21-30
    • Misawa, E.1    Sakurai, T.2    Yamada, M.3    Hayasawa, H.4    Motoyoshi, K.5
  • 49
    • 33744910591 scopus 로고    scopus 로고
    • Antitumor activity of IFN-lambda in murine tumor models
    • Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T (2006) Antitumor activity of IFN-lambda in murine tumor models. J Immunol 176: 7686-7694.
    • (2006) J Immunol , vol.176 , pp. 7686-7694
    • Sato, A.1    Ohtsuki, M.2    Hata, M.3    Kobayashi, E.4    Murakami, T.5
  • 50
    • 0347320749 scopus 로고    scopus 로고
    • In vivo antitumor activity of interleukin 21 mediated by natural killer cells
    • Wang G, Tschoi M, Spolski R, Lou Y, Ozaki K, et al. (2003) In vivo antitumor activity of interleukin 21 mediated by natural killer cells. Cancer Res 63: 9016-9022.
    • (2003) Cancer Res , vol.63 , pp. 9016-9022
    • Wang, G.1    Tschoi, M.2    Spolski, R.3    Lou, Y.4    Ozaki, K.5
  • 51
    • 0036605090 scopus 로고    scopus 로고
    • Overexpression of interleukin-15 in vivo enhances antitumor activity against MHC class I-negative and -positive malignant melanoma through augmented NK activity and cytotoxic T-cell response
    • Yajima T, Nishimura H, Wajjwalku W, Harada M, Kuwano H, et al. (2002) Overexpression of interleukin-15 in vivo enhances antitumor activity against MHC class I-negative and -positive malignant melanoma through augmented NK activity and cytotoxic T-cell response. Int J Cancer 99: 573-578.
    • (2002) Int J Cancer , vol.99 , pp. 573-578
    • Yajima, T.1    Nishimura, H.2    Wajjwalku, W.3    Harada, M.4    Kuwano, H.5
  • 52
    • 0034664870 scopus 로고    scopus 로고
    • Cationic lipid gene transfer of an IL-2 transgene leads to activation of natural killer cells in a SCID mouse human tumor xenograft
    • Clark PR, Stopeck AT, Parker SE, Hersh EM (2000) Cationic lipid gene transfer of an IL-2 transgene leads to activation of natural killer cells in a SCID mouse human tumor xenograft. Cell Immunol 204: 96-104.
    • (2000) Cell Immunol , vol.204 , pp. 96-104
    • Clark, P.R.1    Stopeck, A.T.2    Parker, S.E.3    Hersh, E.M.4
  • 53
    • 23244451649 scopus 로고    scopus 로고
    • In vivo hydrodynamic delivery of cDNA encoding IL-2: Rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells
    • Ortaldo JR, Winkler-Pickett RT, Bere EW, Jr., Watanabe M, Murphy WJ, et al. (2005) In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells. J Immunol 175: 693-699.
    • (2005) J Immunol , vol.175 , pp. 693-699
    • Ortaldo, J.R.1    Winkler-Pickett, R.T.2    Bere Jr., E.W.3    Watanabe, M.4    Murphy, W.J.5
  • 54
    • 0023605471 scopus 로고
    • Systematic preclinical study on the therapeutic properties of recombinant human interleukin 2 for the treatment of metastatic disease
    • Talmadge JE, Phillips H, Schindler J, Tribble H, Pennington R (1987) Systematic preclinical study on the therapeutic properties of recombinant human interleukin 2 for the treatment of metastatic disease. Cancer Res 47: 5725-5732.
    • (1987) Cancer Res , vol.47 , pp. 5725-5732
    • Talmadge, J.E.1    Phillips, H.2    Schindler, J.3    Tribble, H.4    Pennington, R.5
  • 55
    • 0029100898 scopus 로고
    • Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line
    • Ye J, Ortaldo JR, Conlon K, Winkler-Pickett R, Young HA (1995) Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line. J Leukoc Biol 58: 225-233.
    • (1995) J Leukoc Biol , vol.58 , pp. 225-233
    • Ye, J.1    Ortaldo, J.R.2    Conlon, K.3    Winkler-Pickett, R.4    Young, H.A.5
  • 56
    • 0029060681 scopus 로고
    • Early-appearing tumour-infiltrating natural killer cells play a crucial role in the generation of anti-tumour T lymphocytes
    • Kurosawa S, Harada M, Matsuzaki G, Shinomiya Y, Terao H, et al. (1995) Early-appearing tumour-infiltrating natural killer cells play a crucial role in the generation of anti-tumour T lymphocytes. Immunology 85: 338-346.
    • (1995) Immunology , vol.85 , pp. 338-346
    • Kurosawa, S.1    Harada, M.2    Matsuzaki, G.3    Shinomiya, Y.4    Terao, H.5
  • 57
    • 0023226808 scopus 로고
    • Immunomodulatory and immunotherapeutic properties of recombinant gamma- interferon and recombinant tumor necrosis factor in mice
    • Talmadge JE, Tribble HR, Pennington RW, Phillips H, Wiltrout RH (1987) Immunomodulatory and immunotherapeutic properties of recombinant gamma- interferon and recombinant tumor necrosis factor in mice. Cancer Res 47: 2563-2570
    • (1987) Cancer Res , vol.47 , pp. 2563-2570
    • Talmadge, J.E.1    Tribble, H.R.2    Pennington, R.W.3    Phillips, H.4    Wiltrout, R.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.