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Volumn 20, Issue SUPPL. 4, 2009, Pages

Immunotherapy of distant metastatic disease

Author keywords

Adoptive immunotherapy; Anti CTLA 4; Interferon; Interleukin; Metastatic melanoma; Vaccine

Indexed keywords

CANCER VACCINE;

EID: 70349575098     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdp253     Document Type: Article
Times cited : (48)

References (101)
  • 1
    • 0035881074 scopus 로고    scopus 로고
    • Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma
    • Balch CM, Buzaid AC, Soong SJ et al. Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 2001; 19: 3635-3648.
    • (2001) J Clin Oncol , vol.19 , pp. 3635-3648
    • Balch, C.M.1    Buzaid, A.C.2    Soong, S.J.3
  • 2
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
    • Atkins MB, Lotze MT, Dutcher JP et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 1999; 17: 2105-2116.
    • (1999) J Clin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3
  • 3
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • Tsao H, Atkins MB, Sober AJ. Management of cutaneous melanoma. N Engl J Med 2004; 351: 998-1012.
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 4
    • 0031718717 scopus 로고    scopus 로고
    • Results of interleukin-2-based treatment in advanced melanoma: a case record-based analysis of 631 patients
    • Keilholz U, Conradt C, Legha SS et al. Results of interleukin-2-based treatment in advanced melanoma: a case record-based analysis of 631 patients. J Clin Oncol 1998; 16: 2921-2929.
    • (1998) J Clin Oncol , vol.16 , pp. 2921-2929
    • Keilholz, U.1    Conradt, C.2    Legha, S.S.3
  • 5
    • 0035425425 scopus 로고    scopus 로고
    • Factors associated with response to highdose interleukin-2 in patients with metastatic melanoma
    • Phan GQ, Attia P, Steinberg SM et al. Factors associated with response to highdose interleukin-2 in patients with metastatic melanoma. J Clin Oncol 2001; 19: 3477-3482.
    • (2001) J Clin Oncol , vol.19 , pp. 3477-3482
    • Phan, G.Q.1    Attia, P.2    Steinberg, S.M.3
  • 6
    • 25144493776 scopus 로고    scopus 로고
    • Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model
    • Schmidt H, Bastholt L, Geertsen P et al. Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model. Br J Cancer 2005; 93: 273-278.
    • (2005) Br J Cancer , vol.93 , pp. 273-278
    • Schmidt, H.1    Bastholt, L.2    Geertsen, P.3
  • 7
    • 34248218014 scopus 로고    scopus 로고
    • Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with American Joint Committee on Cancer Stage IV Melanoma: results of the EORTC 18951 biochemotherapy trial
    • Schmidt H, Suciu S, Punt CJ et al. Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with American Joint Committee on Cancer Stage IV Melanoma: results of the EORTC 18951 biochemotherapy trial. J Clin Oncol 2007; 25: 1562-1569.
    • (2007) J Clin Oncol , vol.25 , pp. 1562-1569
    • Schmidt, H.1    Suciu, S.2    Punt, C.J.3
  • 8
    • 34548543781 scopus 로고    scopus 로고
    • Durable complete responses with high-dose bolus interleukin-2 in patients with metastatic melanoma who have experienced progression after biochemotherapy
    • Tarhini AA, Kirkwood JM, Gooding WE et al. Durable complete responses with high-dose bolus interleukin-2 in patients with metastatic melanoma who have experienced progression after biochemotherapy. J Clin Oncol 2007; 25: 3802-3807.
    • (2007) J Clin Oncol , vol.25 , pp. 3802-3807
    • Tarhini, A.A.1    Kirkwood, J.M.2    Gooding, W.E.3
  • 9
    • 34548337157 scopus 로고    scopus 로고
    • Single-agent interleukin-2 in the treatment of metastatic melanoma: a systematic review
    • Petrella T, Quirt I, Verma S et al. Single-agent interleukin-2 in the treatment of metastatic melanoma: a systematic review. Cancer Treat Rev 2007; 33: 484-496.
    • (2007) Cancer Treat Rev , vol.33 , pp. 484-496
    • Petrella, T.1    Quirt, I.2    Verma, S.3
  • 10
    • 0031064517 scopus 로고    scopus 로고
    • The role of interferon alfa in the treatment of metastatic melanoma
    • Legha SS. The role of interferon alfa in the treatment of metastatic melanoma. Semin Oncol 1997; 24: S24-S31.
    • (1997) Semin Oncol , vol.24
    • Legha, S.S.1
  • 11
    • 0037099637 scopus 로고    scopus 로고
    • Treating cancer with PEG Intron: pharmacokinetic profile and dosing guidelines for an improved interferonalpha-2b formulation
    • Bukowski RM, Tendler C, Cutler D et al. Treating cancer with PEG Intron: pharmacokinetic profile and dosing guidelines for an improved interferonalpha-2b formulation. Cancer 2002; 95: 389-396.
    • (2002) Cancer , vol.95 , pp. 389-396
    • Bukowski, R.M.1    Tendler, C.2    Cutler, D.3
  • 12
    • 33644970827 scopus 로고    scopus 로고
    • Randomized dose-escalation study evaluating peginterferon alfa-2a in patients with metastatic malignant melanoma
    • Dummer R, Garbe C, Thompson JA et al. Randomized dose-escalation study evaluating peginterferon alfa-2a in patients with metastatic malignant melanoma. J Clin Oncol 2006; 24: 1188-1194.
    • (2006) J Clin Oncol , vol.24 , pp. 1188-1194
    • Dummer, R.1    Garbe, C.2    Thompson, J.A.3
  • 13
    • 53149115610 scopus 로고    scopus 로고
    • Combined treatment with pegylated interferon-alpha-2a and dacarbazine in patients with advanced metastatic melanoma: a phase 2 study
    • Hauschild A, Dummer R, Ugurel S et al. Combined treatment with pegylated interferon-alpha-2a and dacarbazine in patients with advanced metastatic melanoma: a phase 2 study. Cancer 2008; 113: 1404-1411.
    • (2008) Cancer , vol.113 , pp. 1404-1411
    • Hauschild, A.1    Dummer, R.2    Ugurel, S.3
  • 14
    • 41549134676 scopus 로고    scopus 로고
    • Temozolomide plus pegylated interferon alfa-2b as first-line treatment for stage IV melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group (DeCOG)
    • Spieth K, Kaufmann R, Dummer R et al. Temozolomide plus pegylated interferon alfa-2b as first-line treatment for stage IV melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group (DeCOG). Ann Oncol 2008; 19: 801-806.
    • (2008) Ann Oncol , vol.19 , pp. 801-806
    • Spieth, K.1    Kaufmann, R.2    Dummer, R.3
  • 15
    • 0027524697 scopus 로고
    • Randomized phase III trial of treatment with high-dose interleukin-2 either alone or in combination with interferon alfa-2a in patients with advanced melanoma
    • Sparano JA, Fisher RI, Sunderland M et al. Randomized phase III trial of treatment with high-dose interleukin-2 either alone or in combination with interferon alfa-2a in patients with advanced melanoma. J Clin Oncol 1993; 11: 1969-1977.
    • (1993) J Clin Oncol , vol.11 , pp. 1969-1977
    • Sparano, J.A.1    Fisher, R.I.2    Sunderland, M.3
  • 16
    • 0029027251 scopus 로고
    • Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer
    • Marincola FM, White DE, Wise AP, Rosenberg SA. Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer. J Clin Oncol 1995; 13: 1110-1122.
    • (1995) J Clin Oncol , vol.13 , pp. 1110-1122
    • Marincola, F.M.1    White, D.E.2    Wise, A.P.3    Rosenberg, S.A.4
  • 17
    • 40649104646 scopus 로고    scopus 로고
    • Biochemotherapy for the treatment of metastatic malignant melanoma: a systematic review
    • Hamm C, Verma S, Petrella T et al. Biochemotherapy for the treatment of metastatic malignant melanoma: a systematic review. Cancer Treat Rev 2008; 34: 145-156.
    • (2008) Cancer Treat Rev , vol.34 , pp. 145-156
    • Hamm, C.1    Verma, S.2    Petrella, T.3
  • 18
    • 36849061558 scopus 로고    scopus 로고
    • Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: a meta-analysis of 18 trials involving 2 621 patients
    • Ives NJ, Stowe RL, Lorigan P, Wheatley K. Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: a meta-analysis of 18 trials involving 2,621 patients. J Clin Oncol 2007; 25: 5426-5434.
    • (2007) J Clin Oncol , vol.25 , pp. 5426-5434
    • Ives, N.J.1    Stowe, R.L.2    Lorigan, P.3    Wheatley, K.4
  • 19
    • 0025837770 scopus 로고
    • Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma
    • Falkson CI, Falkson G, Falkson HC. Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma. J Clin Oncol 1991; 9: 1403-1408.
    • (1991) J Clin Oncol , vol.9 , pp. 1403-1408
    • Falkson, C.I.1    Falkson, G.2    Falkson, H.C.3
  • 20
    • 17944398659 scopus 로고
    • Interferon-alpha 2a does not improve response or survival when combined with dacarbazine in metastatic malignant melanoma: results of a multi-institutional Australian randomized trial
    • Thomson DB, Adena M, McLeod GR et al. Interferon-alpha 2a does not improve response or survival when combined with dacarbazine in metastatic malignant melanoma: results of a multi-institutional Australian randomized trial. Melanoma Res 1993; 3: 133-138.
    • (1993) Melanoma Res , vol.3 , pp. 133-138
    • Thomson, D.B.1    Adena, M.2    McLeod, G.R.3
  • 21
    • 0028218050 scopus 로고
    • Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon alfa-2a in the treatment of advanced melanoma
    • Bajetta E, Di Leo A, Zampino MG et al. Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon alfa-2a in the treatment of advanced melanoma. J Clin Oncol 1994; 12: 806-811.
    • (1994) J Clin Oncol , vol.12 , pp. 806-811
    • Bajetta, E.1    Di Leo, A.2    Zampino, M.G.3
  • 22
    • 0031805725 scopus 로고    scopus 로고
    • Phase III trial of dacarbazine versus dacarbazine with interferon alpha-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alpha-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group study
    • Falkson CI, Ibrahim J, Kirkwood JM et al. Phase III trial of dacarbazine versus dacarbazine with interferon alpha-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alpha-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group study. J Clin Oncol 1998; 16: 1743-1751.
    • (1998) J Clin Oncol , vol.16 , pp. 1743-1751
    • Falkson, C.I.1    Ibrahim, J.2    Kirkwood, J.M.3
  • 23
    • 0034052426 scopus 로고    scopus 로고
    • A randomized phase III study comparing dacarbazine, BCNU, cisplatin and tamoxifen with dacarbazine and interferon in advanced melanoma
    • Middleton MR, Lorigan P, Owen J et al. A randomized phase III study comparing dacarbazine, BCNU, cisplatin and tamoxifen with dacarbazine and interferon in advanced melanoma. Br J Cancer 2000; 82: 1158-1162.
    • (2000) Br J Cancer , vol.82 , pp. 1158-1162
    • Middleton, M.R.1    Lorigan, P.2    Owen, J.3
  • 24
    • 0035688508 scopus 로고    scopus 로고
    • Prospective randomized comparison of dacarbazine (DTIC) versus DTIC plus interferon-alpha (IFN-alpha) in metastatic melanoma
    • Young AM, Marsden J, Goodman A et al. Prospective randomized comparison of dacarbazine (DTIC) versus DTIC plus interferon-alpha (IFN-alpha) in metastatic melanoma. Clin Oncol (R Coll Radiol) 2001; 13: 458-465.
    • (2001) Clin Oncol (R Coll Radiol) , vol.13 , pp. 458-465
    • Young, A.M.1    Marsden, J.2    Goodman, A.3
  • 25
    • 33644811013 scopus 로고    scopus 로고
    • Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group
    • Kaufmann R, Spieth K, Leiter U et al. Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group. J Clin Oncol 2005; 23: 9001-9007.
    • (2005) J Clin Oncol , vol.23 , pp. 9001-9007
    • Kaufmann, R.1    Spieth, K.2    Leiter, U.3
  • 26
    • 23744493073 scopus 로고    scopus 로고
    • Randomized trial of dacarbazine versus bleomycin, vincristine, lomustine and dacarbazine (BOLD) chemotherapy combined with natural or recombinant interferon-alpha in patients with advanced melanoma
    • Vuoristo MS, Hahka-Kemppinen M, Parvinen LM et al. Randomized trial of dacarbazine versus bleomycin, vincristine, lomustine and dacarbazine (BOLD) chemotherapy combined with natural or recombinant interferon-alpha in patients with advanced melanoma. Melanoma Res 2005; 15: 291-296.
    • (2005) Melanoma Res , vol.15 , pp. 291-296
    • Vuoristo, M.S.1    Hahka-Kemppinen, M.2    Parvinen, L.M.3
  • 27
    • 0036137546 scopus 로고    scopus 로고
    • Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma
    • Agarwala SS, Glaspy J, O'Day SJ et al. Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma. J Clin Oncol 2002; 20: 125-133.
    • (2002) J Clin Oncol , vol.20 , pp. 125-133
    • Agarwala, S.S.1    Glaspy, J.2    O'Day, S.J.3
  • 28
    • 0342894822 scopus 로고    scopus 로고
    • Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group
    • Keilholz U, Goey SH, Punt CJ et al. Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group. J Clin Oncol 1997; 15: 2579-2588.
    • (1997) J Clin Oncol , vol.15 , pp. 2579-2588
    • Keilholz, U.1    Goey, S.H.2    Punt, C.J.3
  • 29
    • 0031936639 scopus 로고    scopus 로고
    • Randomized phase II trial of BCDT [carmustine (BCNU), cisplatin, dacarbazine (DTIC) and tamoxifen] with or without interferon alpha (IFN-alpha) and interleukin (IL-2) in patients with metastatic melanoma
    • Johnston SR, Constenla DO, Moore J et al. Randomized phase II trial of BCDT [carmustine (BCNU), cisplatin, dacarbazine (DTIC) and tamoxifen] with or without interferon alpha (IFN-alpha) and interleukin (IL-2) in patients with metastatic melanoma. Br J Cancer 1998; 77: 1280-1286.
    • (1998) Br J Cancer , vol.77 , pp. 1280-1286
    • Johnston, S.R.1    Constenla, D.O.2    Moore, J.3
  • 30
    • 0344791670 scopus 로고    scopus 로고
    • Randomized trial of treatment with cisplatin and interleukin-2 either alone or in combination with interferon-alpha-2a in patients with metastatic melanoma: a Federation Nationale des Centres de Lutte Contre le Cancer Multicenter, parallel study
    • Dorval T, Negrier S, Chevreau C et al. Randomized trial of treatment with cisplatin and interleukin-2 either alone or in combination with interferon-alpha-2a in patients with metastatic melanoma: a Federation Nationale des Centres de Lutte Contre le Cancer Multicenter, parallel study. Cancer 1999; 85: 1060-1066.
    • (1999) Cancer , vol.85 , pp. 1060-1066
    • Dorval, T.1    Negrier, S.2    Chevreau, C.3
  • 31
    • 0032976897 scopus 로고    scopus 로고
    • Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b
    • Rosenberg SA, Yang JC, Schwartzentruber DJ et al. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b. J Clin Oncol 1999; 17: 968-975.
    • (1999) J Clin Oncol , vol.17 , pp. 968-975
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 32
    • 17744388962 scopus 로고    scopus 로고
    • Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG)
    • Hauschild A, Garbe C, Stolz W et al. Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG). Br J Cancer 2001; 84: 1036-1042.
    • (2001) Br J Cancer , vol.84 , pp. 1036-1042
    • Hauschild, A.1    Garbe, C.2    Stolz, W.3
  • 33
    • 0037089629 scopus 로고    scopus 로고
    • Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial
    • Eton O, Legha SS, Bedikian AY et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial. J Clin Oncol 2002; 20: 2045-2052.
    • (2002) J Clin Oncol , vol.20 , pp. 2045-2052
    • Eton, O.1    Legha, S.S.2    Bedikian, A.Y.3
  • 34
    • 18244365876 scopus 로고    scopus 로고
    • Combination chemotherapy with or without s.c IL-2 and IFN-alpha: results of a prospectively randomized trial of the Cooperative Advanced Malignant Melanoma Chemoimmunotherapy Group (ACIMM)
    • Atzpodien J, Neuber K, Kamanabrou D et al. Combination chemotherapy with or without s.c. IL-2 and IFN-alpha: results of a prospectively randomized trial of the Cooperative Advanced Malignant Melanoma Chemoimmunotherapy Group (ACIMM). Br J Cancer 2002; 86: 179-184.
    • (2002) Br J Cancer , vol.86 , pp. 179-184
    • Atzpodien, J.1    Neuber, K.2    Kamanabrou, D.3
  • 35
    • 0037087755 scopus 로고    scopus 로고
    • Cisplatin, dacarbazine with or without subcutaneous interleukin-2, and interferon alpha-2b in advanced melanoma outpatients: results from an Italian multicenter phase III randomized clinical trial
    • Ridolfi R, Chiarion-Sileni V, Guida M et al. Cisplatin, dacarbazine with or without subcutaneous interleukin-2, and interferon alpha-2b in advanced melanoma outpatients: results from an Italian multicenter phase III randomized clinical trial. J Clin Oncol 2002; 20: 1600-1607.
    • (2002) J Clin Oncol , vol.20 , pp. 1600-1607
    • Ridolfi, R.1    Chiarion-Sileni, V.2    Guida, M.3
  • 36
    • 27244432257 scopus 로고    scopus 로고
    • Dacarbazine, cisplatin, and interferon-alfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group
    • Keilholz U, Punt CJ, Gore M et al. Dacarbazine, cisplatin, and interferon-alfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group. J Clin Oncol 2005; 23: 6747-6755.
    • (2005) J Clin Oncol , vol.23 , pp. 6747-6755
    • Keilholz, U.1    Punt, C.J.2    Gore, M.3
  • 37
    • 33645275176 scopus 로고    scopus 로고
    • Multicenter phase III randomized trial of polychemotherapy (CVD regimen) versus the same chemotherapy (CT) plus subcutaneous interleukin-2 and interferon-alpha2b in metastatic melanoma
    • Bajetta E, Del Vecchio M, Nova P et al. Multicenter phase III randomized trial of polychemotherapy (CVD regimen) versus the same chemotherapy (CT) plus subcutaneous interleukin-2 and interferon-alpha2b in metastatic melanoma. Ann Oncol 2006; 17: 571-577.
    • (2006) Ann Oncol , vol.17 , pp. 571-577
    • Bajetta, E.1    Del Vecchio, M.2    Nova, P.3
  • 38
    • 53949108399 scopus 로고    scopus 로고
    • Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group
    • Atkins MB, Hsu J, Lee S et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 2008; 26: 5748-5754.
    • (2008) J Clin Oncol , vol.26 , pp. 5748-5754
    • Atkins, M.B.1    Hsu, J.2    Lee, S.3
  • 39
    • 37249029836 scopus 로고    scopus 로고
    • Interleukin-21 signaling: functions in cancer and autoimmunity
    • Davis ID, Skak K, Smyth MJ et al. Interleukin-21 signaling: functions in cancer and autoimmunity. Clin Cancer Res 2007; 13: 6926-6932.
    • (2007) Clin Cancer Res , vol.13 , pp. 6926-6932
    • Davis, I.D.1    Skak, K.2    Smyth, M.J.3
  • 41
    • 42949139835 scopus 로고    scopus 로고
    • Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma
    • Thompson JA, Curti BD, Redman BG et al. Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma. J Clin Oncol 2008; 26: 2034-2039.
    • (2008) J Clin Oncol , vol.26 , pp. 2034-2039
    • Thompson, J.A.1    Curti, B.D.2    Redman, B.G.3
  • 42
    • 48149096869 scopus 로고    scopus 로고
    • IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma
    • Frederiksen KS, Lundsgaard D, Freeman JA et al. IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunol Immunother 2008; 57: 1439-1449.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1439-1449
    • Frederiksen, K.S.1    Lundsgaard, D.2    Freeman, J.A.3
  • 44
    • 33846465547 scopus 로고    scopus 로고
    • Immunostimulatory monoclonal antibodies for cancer therapy
    • Melero I, Hervas-Stubbs S, Glennie M et al. Immunostimulatory monoclonal antibodies for cancer therapy. Nat Rev Cancer 2007; 7: 95-106.
    • (2007) Nat Rev Cancer , vol.7 , pp. 95-106
    • Melero, I.1    Hervas-Stubbs, S.2    Glennie, M.3
  • 45
    • 36849035139 scopus 로고    scopus 로고
    • Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies
    • O'Day SJ, Hamid O, Urba WJ. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 2007; 110: 2614-2627.
    • (2007) Cancer , vol.110 , pp. 2614-2627
    • O'Day, S.J.1    Hamid, O.2    Urba, W.J.3
  • 46
    • 36248987929 scopus 로고    scopus 로고
    • The role of the CTLA4 blockade in the treatment of malignant melanoma
    • Cranmer LD, Hersh E. The role of the CTLA4 blockade in the treatment of malignant melanoma. Cancer Invest 2007; 25: 613-631.
    • (2007) Cancer Invest , vol.25 , pp. 613-631
    • Cranmer, L.D.1    Hersh, E.2
  • 47
    • 34548257760 scopus 로고    scopus 로고
    • Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events
    • Weber J. Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events. Oncologist 2007; 12: 864-872.
    • (2007) Oncologist , vol.12 , pp. 864-872
    • Weber, J.1
  • 48
    • 34548240159 scopus 로고    scopus 로고
    • Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
    • Ribas A, Hanson DC, Noe DA et al. Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. Oncologist 2007; 12: 873-883.
    • (2007) Oncologist , vol.12 , pp. 873-883
    • Ribas, A.1    Hanson, D.C.2    Noe, D.A.3
  • 49
    • 55949101240 scopus 로고    scopus 로고
    • Disease control and long-term survival in chemotherapy-naive patients with advanced melanoma treated with ipilimumab (MDX- 010) with or without dacarbazine 2008 ASCO Annual proceedings Part I
    • Abstr 9022
    • Hersh EM, Weber JS, Powderly JD et al. Disease control and long-term survival in chemotherapy-naive patients with advanced melanoma treated with ipilimumab (MDX- 010) with or without dacarbazine. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9022.
    • (2008) J Clin Oncol , vol.26
    • Hersh, E.M.1    Weber, J.S.2    Powderly, J.D.3
  • 50
    • 24944459890 scopus 로고    scopus 로고
    • Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
    • Attia P, Phan GQ, Maker AV et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005; 23: 6043-6053.
    • (2005) J Clin Oncol , vol.23 , pp. 6043-6053
    • Attia, P.1    Phan, G.Q.2    Maker, A.V.3
  • 51
    • 36748999428 scopus 로고    scopus 로고
    • Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
    • Downey SG, Klapper JA, Smith FO et al. Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade. Clin Cancer Res 2007; 13: 6681-6688.
    • (2007) Clin Cancer Res , vol.13 , pp. 6681-6688
    • Downey, S.G.1    Klapper, J.A.2    Smith, F.O.3
  • 52
    • 33744792341 scopus 로고    scopus 로고
    • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
    • Beck KE, Blansfield JA, Tran KQ et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006; 24: 2283-2289.
    • (2006) J Clin Oncol , vol.24 , pp. 2283-2289
    • Beck, K.E.1    Blansfield, J.A.2    Tran, K.Q.3
  • 53
    • 55949133643 scopus 로고    scopus 로고
    • Dose effect of ipilimumab in patients with advanced melanoma: Results from a phase II, randomized, dose-ranging study 2008 ASCO Annual proceedings Part I
    • Abstr 9025
    • Hamid O, Chin K, Li J et al. Dose effect of ipilimumab in patients with advanced melanoma: Results from a phase II, randomized, dose-ranging study. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9025.
    • (2008) J Clin Oncol , vol.26
    • Hamid, O.1    Chin, K.2    Li, J.3
  • 54
    • 84858856897 scopus 로고    scopus 로고
    • Efficacy and safety of ipilimumab induction and maintenance dosing in patients with advanced melanoma who progressed on one or more prior therapies ASCO Annual proceedings Part I
    • Abstr 9021
    • O'Day SJ, Ibrahim R, DePril V et al. Efficacy and safety of ipilimumab induction and maintenance dosing in patients with advanced melanoma who progressed on one or more prior therapies. ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9021.
    • (2008) J Clin Oncol , vol.26
    • O'Day, S.J.1    Ibrahim, R.2    DePril, V.3
  • 55
    • 84858838621 scopus 로고    scopus 로고
    • Antitumor response and new lesions in advanced melanoma patients on ipilimumab treatment ASCO Annual proceedings Part I
    • Abstr 3020
    • Wolchok JD, Ibrahim R, DePril V et al. Antitumor response and new lesions in advanced melanoma patients on ipilimumab treatment. ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 3020.
    • (2008) J Clin Oncol , vol.26
    • Wolchok, J.D.1    Ibrahim, R.2    DePril, V.3
  • 56
    • 84858843019 scopus 로고    scopus 로고
    • Novel efficacy criteria for antitumor activity to immunotherapy using the example of ipilimumab, an anti-CTLA-4 monoclonal antibody ASCO Annual Proceedings Part I
    • Abstr 3008
    • Hodi FS, Hoos A, Ibrahim R et al. Novel efficacy criteria for antitumor activity to immunotherapy using the example of ipilimumab, an anti-CTLA-4 monoclonal antibody. ASCO Annual Proceedings Part I. J Clin Oncol 2008; 26: Abstr 3008.
    • (2008) J Clin Oncol , vol.26
    • Hodi, F.S.1    Hoos, A.2    Ibrahim, R.3
  • 57
    • 37049011353 scopus 로고    scopus 로고
    • Results of a phase II clinical trial of 2 doses and schedules of CP-675,206, an anti-CTLA4 monoclonal antibody, in patients (pts) with advanced melanoma ASCO Annual Meeting Proceedings Part I
    • Abstr 3000
    • Ribas A, Antonia S, Sosman J et al. Results of a phase II clinical trial of 2 doses and schedules of CP-675,206, an anti-CTLA4 monoclonal antibody, in patients (pts) with advanced melanoma. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007; 25: Abstr 3000.
    • (2007) J Clin Oncol , vol.25
    • Ribas, A.1    Antonia, S.2    Sosman, J.3
  • 58
    • 41149155378 scopus 로고    scopus 로고
    • Survival of patients (pts) with metastatic melanoma treated with the anti-CTLA4 monoclonal antibody (mAb) CP-675 206 in a phase I/II study. ASCO Annual Meeting Proceedings Part I
    • Abstr 8524
    • Gomez-Navarro J, Antonia S, Sosman J et al. Survival of patients (pts) with metastatic melanoma treated with the anti-CTLA4 monoclonal antibody (mAb) CP-675,206 in a phase I/II study. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007; 26: Abstr 8524.
    • (2007) J Clin Oncol , vol.26
    • Gomez-Navarro, J.1    Antonia, S.2    Sosman, J.3
  • 59
    • 84858848438 scopus 로고    scopus 로고
    • A phase II trial of tremelimumab (CP-675 206) in patients with advanced refractory or relapsed melanoma. ASCO Annual proceedings Part I
    • Abstr 9023
    • Kirkwood JM, Lorigan P, Hersey P et al. A phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma. ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9023.
    • (2008) J Clin Oncol , vol.26
    • Kirkwood, J.M.1    Lorigan, P.2    Hersey, P.3
  • 60
    • 55949137090 scopus 로고    scopus 로고
    • Phase III, open-label, randomized, comparative study of tremelimumab (CP-675 206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma. 2008 ASCO Annual proceedings Part I
    • Abstr LBA9011
    • Ribas A, Hauschild A, Kefford R et al. Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr LBA9011.
    • (2008) J Clin Oncol , vol.26
    • Ribas, A.1    Hauschild, A.2    Kefford, R.3
  • 61
    • 84858814810 scopus 로고    scopus 로고
    • Phase II trial of combination biotherapy of high-dose interferon alfa-2b and tremelimumab for recurrent inoperable stage III or stage IV melanoma 2008 ASCO Annual proceedings Part I
    • Abstr 9009
    • Tarhini AA, Moschos SS, Schlesselman JJ et al. Phase II trial of combination biotherapy of high-dose interferon alfa-2b and tremelimumab for recurrent inoperable stage III or stage IV melanoma. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9009.
    • (2008) J Clin Oncol , vol.26
    • Tarhini, A.A.1    Moschos, S.S.2    Schlesselman, J.J.3
  • 62
    • 34548512807 scopus 로고    scopus 로고
    • Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb
    • Li B, Lin J, Vanroey M et al. Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb. Clin Immunol 2007; 125: 76-87.
    • (2007) Clin Immunol , vol.125 , pp. 76-87
    • Li, B.1    Lin, J.2    Vanroey, M.3
  • 63
    • 34548759728 scopus 로고    scopus 로고
    • Mechanisms involved in synergistic anticancer immunity of anti-4-1BB and anti-CD4 therapy
    • Choi BK, Kim YH, Kang WJ et al. Mechanisms involved in synergistic anticancer immunity of anti-4-1BB and anti-CD4 therapy. Cancer Res 2007; 67: 8891-8899.
    • (2007) Cancer Res , vol.67 , pp. 8891-8899
    • Choi, B.K.1    Kim, Y.H.2    Kang, W.J.3
  • 64
    • 55949113750 scopus 로고    scopus 로고
    • Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA) 2008 ASCO Annual proceedings Part I
    • Abstr 3007
    • Sznol M, Hodi FS, Margolin K et al. Phase I study of BMS-663513, a fully human anti-CD137 agonist monoclonal antibody, in patients (pts) with advanced cancer (CA). 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 3007.
    • (2008) J Clin Oncol , vol.26
    • Sznol, M.1    Hodi, F.S.2    Margolin, K.3
  • 65
    • 2442488748 scopus 로고    scopus 로고
    • CNTO 95 a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo
    • Trikha M, Zhou Z, Nemeth JA et al. CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo. Int J Cancer 2004; 110: 326-335.
    • (2004) Int J Cancer , vol.110 , pp. 326-335
    • Trikha, M.1    Zhou, Z.2    Nemeth, J.A.3
  • 66
    • 84858849928 scopus 로고    scopus 로고
    • Phase I study of CNTO 95 a fully human monoclonal antibody (mAb) to av integrins, in patients with solid tumors 2005 ASCO Annual Meeting Proceedings Part I
    • Abstr 3113
    • Jayson GC, Mullamitha S, Ton C et al. Phase I study of CNTO 95, a fully human monoclonal antibody (mAb) to av integrins, in patients with solid tumors. 2005 ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2005; 23: Abstr 3113.
    • (2005) J Clin Oncol , vol.23
    • Jayson, G.C.1    Mullamitha, S.2    Ton, C.3
  • 67
    • 84858825764 scopus 로고    scopus 로고
    • Phase II study of volociximab (M200), an α5β1 anti-integrin antibody in metastatic melanoma 2005 ASCO Annual Meeting Proceedings Part I
    • Abstr 8011
    • Cranmer LD, Bedikian AY, Ribas A et al. Phase II study of volociximab (M200), an α5β1 anti-integrin antibody in metastatic melanoma. 2005 ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2005; 24: Abstr 8011.
    • (2005) J Clin Oncol , vol.24
    • Cranmer, L.D.1    Bedikian, A.Y.2    Ribas, A.3
  • 68
    • 77950416261 scopus 로고    scopus 로고
    • A multicenter phase II study of volociximab in patients with relapsed metastatic melanoma 2008 ASCO Annual proceedings Part I
    • Abstr 3505
    • Linette G, Cranmer L, Hodi S et al. A multicenter phase II study of volociximab in patients with relapsed metastatic melanoma. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008: 26: Abstr 3505.
    • (2008) J Clin Oncol , vol.26
    • Linette, G.1    Cranmer, L.2    Hodi, S.3
  • 69
    • 33846188062 scopus 로고    scopus 로고
    • Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin
    • Mulgrew K, Kinneer K, Yao XT et al. Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin. Mol Cancer Ther 2006; 5: 3122-3129.
    • (2006) Mol Cancer Ther , vol.5 , pp. 3122-3129
    • Mulgrew, K.1    Kinneer, K.2    Yao, X.T.3
  • 70
    • 84858804099 scopus 로고    scopus 로고
    • A phase II, randomized, open-label study evaluating the antitumor activity of MEDI-522, a humanized monoclonal antibody directed against the human alpha v beta 3 (avb3) integrin ± dacarbazine (DTIC) in patients with metastatic melanoma (MM). 2005 ASCO Annual Meeting Proceedings Part I
    • Abstr 7507
    • Hersey P, Sosman J, O'Day S et al. A phase II, randomized, open-label study evaluating the antitumor activity of MEDI-522, a humanized monoclonal antibody directed against the human alpha v beta 3 (avb3) integrin, ± dacarbazine (DTIC) in patients with metastatic melanoma (MM). 2005 ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2005; 23: Abstr 7507.
    • (2005) J Clin Oncol , vol.23
    • Hersey, P.1    Sosman, J.2    O'Day, S.3
  • 71
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med 2004; 10: 909-915.
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 72
    • 33646255944 scopus 로고    scopus 로고
    • Allogeneic and autologous melanoma vaccines: where have we been and where are we going?
    • Sondak VK, Sabel MS, Mule JJ. Allogeneic and autologous melanoma vaccines: where have we been and where are we going? Clin Cancer Res 2006; 12: 2337s-2341s.
    • (2006) Clin Cancer Res , vol.12
    • Sondak, V.K.1    Sabel, M.S.2    Mule, J.J.3
  • 73
    • 34548249596 scopus 로고    scopus 로고
    • An international, randomized, phase III trial of bacillus Calmette-Guerin (BCG) plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional or distant sites 2007 ASCO Annual Meeting Proceedings Part I
    • Abstr 8508
    • Morton DL, Mozzillo N, Thompson JF et al. An international, randomized, phase III trial of bacillus Calmette-Guerin (BCG) plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional or distant sites. 2007 ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007; 25: Abstr 8508.
    • (2007) J Clin Oncol , vol.25
    • Morton, D.L.1    Mozzillo, N.2    Thompson, J.F.3
  • 74
    • 0036214288 scopus 로고    scopus 로고
    • Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses
    • Srivastava P. Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu Rev Immunol 2002; 20: 395-425.
    • (2002) Annu Rev Immunol , vol.20 , pp. 395-425
    • Srivastava, P.1
  • 75
    • 0037108696 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings
    • Belli F, Testori A, Rivoltini L et al. Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. J Clin Oncol 2002; 20: 4169-4180.
    • (2002) J Clin Oncol , vol.20 , pp. 4169-4180
    • Belli, F.1    Testori, A.2    Rivoltini, L.3
  • 76
    • 39749186213 scopus 로고    scopus 로고
    • Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group
    • Testori A, Richards J, Whitman E et al. Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group. J Clin Oncol 2008; 26: 955-962.
    • (2008) J Clin Oncol , vol.26 , pp. 955-962
    • Testori, A.1    Richards, J.2    Whitman, E.3
  • 77
    • 0035964396 scopus 로고    scopus 로고
    • A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3
    • Coulie PG, Karanikas V, Colau D et al. A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3. Proc Natl Acad Sci USA 2001; 98: 10290-10295.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10290-10295
    • Coulie, P.G.1    Karanikas, V.2    Colau, D.3
  • 78
    • 84858805658 scopus 로고    scopus 로고
    • Immunization with recombinant MAGE-A3 protein combined with adjuvant systems AS15 or AS02B in patients with unresectable and progressive metastatic cutaneous melanoma: a randomized open-label phase II study of the EORTC Melanoma Group (16032-18031) 2008 ASCO Annual Proceedings Part I
    • Abstr 9065
    • Kruit WH, Suciu S, Dreno B et al. Immunization with recombinant MAGE-A3 protein combined with adjuvant systems AS15 or AS02B in patients with unresectable and progressive metastatic cutaneous melanoma: a randomized open-label phase II study of the EORTC Melanoma Group (16032-18031). 2008 ASCO Annual Proceedings Part I. J Clin Oncol 2008; 26: Abstr 9065.
    • (2008) J Clin Oncol , vol.26
    • Kruit, W.H.1    Suciu, S.2    Dreno, B.3
  • 79
    • 34247891741 scopus 로고    scopus 로고
    • More than one reason to rethink the use of peptides in vaccine design
    • Purcell AW, McCluskey J, Rossjohn J. More than one reason to rethink the use of peptides in vaccine design. Nat Rev Drug Discov 2007; 6: 404-414.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 404-414
    • Purcell, A.W.1    McCluskey, J.2    Rossjohn, J.3
  • 80
    • 42549138499 scopus 로고    scopus 로고
    • Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines
    • Melief CJ, van der Burg SH. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat Rev Cancer 2008; 8: 351-360.
    • (2008) Nat Rev Cancer , vol.8 , pp. 351-360
    • Melief, C.J.1    van der Burg, S.H.2
  • 81
    • 33845773464 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy
    • Osada T, Clay TM, Woo CY et al. Dendritic cell-based immunotherapy. Int Rev Immunol 2006; 25: 377-413.
    • (2006) Int Rev Immunol , vol.25 , pp. 377-413
    • Osada, T.1    Clay, T.M.2    Woo, C.Y.3
  • 82
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thurner B, Haendle I, Roder C et al. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med 1999; 190: 1669-1678.
    • (1999) J Exp Med , vol.190 , pp. 1669-1678
    • Thurner, B.1    Haendle, I.2    Roder, C.3
  • 83
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG
    • Schadendorf D, Ugurel S, Schuler-Thurner B et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG. Ann Oncol 2006; 17: 563-570.
    • (2006) Ann Oncol , vol.17 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3
  • 85
    • 41149108247 scopus 로고    scopus 로고
    • The role of vaccine therapy in the treatment of melanoma
    • Lens M. The role of vaccine therapy in the treatment of melanoma. Expert Opin Biol Ther 2008; 8: 315-323.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 315-323
    • Lens, M.1
  • 86
    • 42549165017 scopus 로고    scopus 로고
    • Intralesional adenovirus-mediated interleukin-2 gene transfer for advanced solid cancers and melanoma
    • Dummer R, Rochlitz C, Velu T et al. Intralesional adenovirus-mediated interleukin-2 gene transfer for advanced solid cancers and melanoma. Mol Ther 2008; 16: 985-994.
    • (2008) Mol Ther , vol.16 , pp. 985-994
    • Dummer, R.1    Rochlitz, C.2    Velu, T.3
  • 87
    • 13844262749 scopus 로고    scopus 로고
    • Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy
    • Heinzerling L, Burg G, Dummer R et al. Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy. Hum Gene Ther 2005; 16: 35-48.
    • (2005) Hum Gene Ther , vol.16 , pp. 35-48
    • Heinzerling, L.1    Burg, G.2    Dummer, R.3
  • 88
    • 34447514483 scopus 로고    scopus 로고
    • Intratumoral injection of IL-12 plasmid DNA-results of a phase I/IB clinical trial
    • Mahvi DM, Henry MB, Albertini MR et al. Intratumoral injection of IL-12 plasmid DNA-results of a phase I/IB clinical trial. Cancer Gene Ther 2007; 14: 717-723.
    • (2007) Cancer Gene Ther , vol.14 , pp. 717-723
    • Mahvi, D.M.1    Henry, M.B.2    Albertini, M.R.3
  • 89
    • 84858813043 scopus 로고    scopus 로고
    • Phase II clinical trial with a second generation, GM-CSF encoding, oncolytic herpesvirus in unresectable metastatic melanoma 2008 ASCO Annual proceedings Part I
    • Abstr 9008
    • Senzer NN, Kaufman HL, Amatruda T et al. Phase II clinical trial with a second generation, GM-CSF encoding, oncolytic herpesvirus in unresectable metastatic melanoma. 2008 ASCO Annual proceedings Part I. J Clin Oncol 2008; 26: Abstr 9008.
    • (2008) J Clin Oncol , vol.26
    • Senzer, N.N.1    Kaufman, H.L.2    Amatruda, T.3
  • 91
    • 0021170244 scopus 로고
    • Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin
    • Mule JJ, Shu S, Schwarz SL, Rosenberg SA. Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin- Science 1984; 225: 1487-1489.
    • (1984) Science , vol.225 , pp. 1487-1489
    • Mule, J.J.1    Shu, S.2    Schwarz, S.L.3    Rosenberg, S.A.4
  • 92
    • 0022473607 scopus 로고
    • A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes
    • Rosenberg SA, Spiess P, Lafreniere R. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science 1986; 233: 1318-1321.
    • (1986) Science , vol.233 , pp. 1318-1321
    • Rosenberg, S.A.1    Spiess, P.2    Lafreniere, R.3
  • 93
    • 0028031582 scopus 로고
    • Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2
    • Rosenberg SA, Yannelli JR, Yang JC et al. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J Natl Cancer Inst 1994; 86: 1159-1166.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1159-1166
    • Rosenberg, S.A.1    Yannelli, J.R.2    Yang, J.C.3
  • 94
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME, Wunderlich JR, Robbins PF et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 2002; 298: 850-854.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3
  • 95
    • 33750940238 scopus 로고    scopus 로고
    • Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma
    • Mackensen A, Meidenbauer N, Vogl S et al. Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma. J Clin Oncol 2006; 24: 5060-5069.
    • (2006) J Clin Oncol , vol.24 , pp. 5060-5069
    • Mackensen, A.1    Meidenbauer, N.2    Vogl, S.3
  • 96
    • 33750343038 scopus 로고    scopus 로고
    • Adoptive transfer of vaccine-induced peripheral blood mononuclear cells to patients with metastatic melanoma following lymphodepletion
    • Powell DJ, Jr, Dudley ME, Hogan KA et al. Adoptive transfer of vaccine-induced peripheral blood mononuclear cells to patients with metastatic melanoma following lymphodepletion. J Immunol 2006; 177: 6527-6539.
    • (2006) J Immunol , vol.177 , pp. 6527-6539
    • Powell Jr., D.J.1    Dudley, M.E.2    Hogan, K.A.3
  • 97
    • 45549099784 scopus 로고    scopus 로고
    • Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
    • Hunder NN, Wallen H, Cao J et al. Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med 2008; 358: 2698-2703.
    • (2008) N Engl J Med , vol.358 , pp. 2698-2703
    • Hunder, N.N.1    Wallen, H.2    Cao, J.3
  • 98
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • Dudley ME, Wunderlich JR, Yang JC et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 2005; 23: 2346-2357.
    • (2005) J Clin Oncol , vol.23 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3
  • 99
    • 41149097574 scopus 로고    scopus 로고
    • Adoptive cell transfer: a clinical path to effective cancer immunotherapy
    • Rosenberg SA, Restifo NP, Yang JC et al. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 2008; 8: 299-308.
    • (2008) Nat Rev Cancer , vol.8 , pp. 299-308
    • Rosenberg, S.A.1    Restifo, N.P.2    Yang, J.C.3
  • 100
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, Dudley ME, Wunderlich JR et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006; 314: 126-129.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 101
    • 59849100381 scopus 로고    scopus 로고
    • Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
    • Tran KQ, Zhou J, Durflinger KH et al. Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy. J Immunother 2008; 31: 742-751.
    • (2008) J Immunother , vol.31 , pp. 742-751
    • Tran, K.Q.1    Zhou, J.2    Durflinger, K.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.