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Volumn 19, Issue 7, 2008, Pages 475-481

Inhibitory effect of dietary n-3 polyunsaturated fatty acids to intestinal IL-15 expression is associated with reduction of TCRαβ+CD8α+CD8β- intestinal intraepithelial lymphocytes

Author keywords

IL 15; Intestinal intraepithelial lymphocytes; n 3 PUFA; Rats

Indexed keywords

CORN OIL; FISH OIL; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 4; OMEGA 3 FATTY ACID; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 44649139904     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.06.008     Document Type: Article
Times cited : (15)

References (47)
  • 1
    • 11144247417 scopus 로고    scopus 로고
    • IL-7 and IL-15: therapeutic cytokines for immunodeficiency
    • Alpdogan O., and van den Brink M.R. IL-7 and IL-15: therapeutic cytokines for immunodeficiency. Trends Immunol 26 (2005) 56-64
    • (2005) Trends Immunol , vol.26 , pp. 56-64
    • Alpdogan, O.1    van den Brink, M.R.2
  • 3
    • 0032589097 scopus 로고    scopus 로고
    • Characterization of CD4+ CD8alphaalpha+ and CD4-CD8alphaalpha+ intestinal intraepithelial lymphocytes in rats
    • Yamada K., Kimura Y., Nishimura H., Namii Y., Murase M., and Yoshikai Y. Characterization of CD4+ CD8alphaalpha+ and CD4-CD8alphaalpha+ intestinal intraepithelial lymphocytes in rats. Int Immunol 11 (1999) 21-28
    • (1999) Int Immunol , vol.11 , pp. 21-28
    • Yamada, K.1    Kimura, Y.2    Nishimura, H.3    Namii, Y.4    Murase, M.5    Yoshikai, Y.6
  • 4
    • 16644368361 scopus 로고    scopus 로고
    • Development of TCR alpha beta CD8 alpha alpha intestinal intraepithelial lymphocytes is promoted by interleukin-15-producing epithelial cells constitutively stimulated by gram-negative bacteria via TLR4
    • Kaneko M., Mizunuma T., Takimoto H., and Kumazawa Y. Development of TCR alpha beta CD8 alpha alpha intestinal intraepithelial lymphocytes is promoted by interleukin-15-producing epithelial cells constitutively stimulated by gram-negative bacteria via TLR4. Biol Pharm Bull 27 (2004) 883-889
    • (2004) Biol Pharm Bull , vol.27 , pp. 883-889
    • Kaneko, M.1    Mizunuma, T.2    Takimoto, H.3    Kumazawa, Y.4
  • 5
    • 24144487439 scopus 로고    scopus 로고
    • Interleukin-7 administration alters intestinal intraepithelial lymphocyte phenotype and function in vivo
    • Yang H., Spencer A.U., and Teitelbaum D.H. Interleukin-7 administration alters intestinal intraepithelial lymphocyte phenotype and function in vivo. Cytokine 31 (2005) 419-428
    • (2005) Cytokine , vol.31 , pp. 419-428
    • Yang, H.1    Spencer, A.U.2    Teitelbaum, D.H.3
  • 6
    • 0035162229 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: exploring the third way in immunology
    • Hayday A., Theodoridis E., Ramsburg E., and Shires J. Intraepithelial lymphocytes: exploring the third way in immunology. Nat Immunol 2 (2001) 997-1003
    • (2001) Nat Immunol , vol.2 , pp. 997-1003
    • Hayday, A.1    Theodoridis, E.2    Ramsburg, E.3    Shires, J.4
  • 7
    • 17444377169 scopus 로고    scopus 로고
    • Cytokine production by intestinal intraepithelial lymphocyte subsets in celiac disease
    • Leon F., Sanchez L., Camarero C., and Roy G. Cytokine production by intestinal intraepithelial lymphocyte subsets in celiac disease. Dig Dis Sci 50 (2005) 593-600
    • (2005) Dig Dis Sci , vol.50 , pp. 593-600
    • Leon, F.1    Sanchez, L.2    Camarero, C.3    Roy, G.4
  • 8
    • 33645118120 scopus 로고    scopus 로고
    • Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease
    • Di Sabatino A., Ciccocioppo R., Cupelli F., et al. Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease. Gut 55 (2006) 469-477
    • (2006) Gut , vol.55 , pp. 469-477
    • Di Sabatino, A.1    Ciccocioppo, R.2    Cupelli, F.3
  • 9
    • 0029744031 scopus 로고    scopus 로고
    • Graft-infiltrating cells in rats receiving orthotopic semiallogeneic small intestine transplantation with portal or systemic venous drainage
    • Sullivan B., Cohen Z., Fu X.M., Levy G., Plapler H., Wojcik D., et al. Graft-infiltrating cells in rats receiving orthotopic semiallogeneic small intestine transplantation with portal or systemic venous drainage. Transplantation 62 (1996) 715-721
    • (1996) Transplantation , vol.62 , pp. 715-721
    • Sullivan, B.1    Cohen, Z.2    Fu, X.M.3    Levy, G.4    Plapler, H.5    Wojcik, D.6
  • 10
    • 0031902546 scopus 로고    scopus 로고
    • Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids
    • Calder P.C. Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Braz J Med Biol Res 31 (1998) 467-490
    • (1998) Braz J Med Biol Res , vol.31 , pp. 467-490
    • Calder, P.C.1
  • 11
    • 16244405611 scopus 로고    scopus 로고
    • Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis
    • Camuesco D., Galvez J., Nieto A., Comalada M., Rodriguez-Cabezas M.E., Concha A., et al. Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J Nutr 135 (2005) 687-694
    • (2005) J Nutr , vol.135 , pp. 687-694
    • Camuesco, D.1    Galvez, J.2    Nieto, A.3    Comalada, M.4    Rodriguez-Cabezas, M.E.5    Concha, A.6
  • 13
    • 0036138758 scopus 로고    scopus 로고
    • Dietary polyunsaturated fatty acids improve histological and biochemical alterations in rats with experimental ulcerative colitis
    • Nieto N., Torres M.I., Rios A., and Gil A. Dietary polyunsaturated fatty acids improve histological and biochemical alterations in rats with experimental ulcerative colitis. J Nutr 132 (2002) 11-19
    • (2002) J Nutr , vol.132 , pp. 11-19
    • Nieto, N.1    Torres, M.I.2    Rios, A.3    Gil, A.4
  • 14
    • 0032442131 scopus 로고    scopus 로고
    • Dietary monounsaturated n-3 and n-6 long-chain polyunsaturated fatty acids affect cellular antioxidant defense system in rats with experimental ulcerative colitis induced by trinitrobenzene sulfonic acid
    • Nieto N., Fernandez M.I., Torres M.I., Rios A., Suarez M.D., and Gil A. Dietary monounsaturated n-3 and n-6 long-chain polyunsaturated fatty acids affect cellular antioxidant defense system in rats with experimental ulcerative colitis induced by trinitrobenzene sulfonic acid. Dig Dis Sci 43 (1998) 2676-2687
    • (1998) Dig Dis Sci , vol.43 , pp. 2676-2687
    • Nieto, N.1    Fernandez, M.I.2    Torres, M.I.3    Rios, A.4    Suarez, M.D.5    Gil, A.6
  • 16
    • 33846595309 scopus 로고    scopus 로고
    • Fish oil ameliorates the allograft arteriosclerosis of intestine on rats
    • Ma H., Wang J., Wang J., Li Y., and Li J. Fish oil ameliorates the allograft arteriosclerosis of intestine on rats. Pediatr Transplant 11 (2007) 173-179
    • (2007) Pediatr Transplant , vol.11 , pp. 173-179
    • Ma, H.1    Wang, J.2    Wang, J.3    Li, Y.4    Li, J.5
  • 18
    • 0026034717 scopus 로고
    • Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation
    • Guy-Grand D., Cerf-Bensussan N., Malissen B., Malassis-Seris M., Briottet C., and Vassalli P. Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med 173 (1991) 471-481
    • (1991) J Exp Med , vol.173 , pp. 471-481
    • Guy-Grand, D.1    Cerf-Bensussan, N.2    Malissen, B.3    Malassis-Seris, M.4    Briottet, C.5    Vassalli, P.6
  • 19
    • 0025936929 scopus 로고
    • Phenotypic complexity of intraepithelial lymphocytes of the small intestine
    • Lefrancois L. Phenotypic complexity of intraepithelial lymphocytes of the small intestine. J Immunol 147 (1991) 1746-1751
    • (1991) J Immunol , vol.147 , pp. 1746-1751
    • Lefrancois, L.1
  • 20
    • 0033625336 scopus 로고    scopus 로고
    • An early expansion of CD8alphabeta T cells, but depletion of resident CD8alphaalpha T cells, occurs in the intestinal epithelium during primary simian immunodeficiency virus infection
    • Mattapallil J.J., Reay E., and Dandekar S. An early expansion of CD8alphabeta T cells, but depletion of resident CD8alphaalpha T cells, occurs in the intestinal epithelium during primary simian immunodeficiency virus infection. Aids 14 (2000) 637-646
    • (2000) Aids , vol.14 , pp. 637-646
    • Mattapallil, J.J.1    Reay, E.2    Dandekar, S.3
  • 21
    • 0037965755 scopus 로고    scopus 로고
    • An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease
    • Das G., Augustine M.M., Das J., Bottomly K., Ray P., and Ray A. An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc Natl Acad Sci U S A 100 (2003) 5324-5329
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5324-5329
    • Das, G.1    Augustine, M.M.2    Das, J.3    Bottomly, K.4    Ray, P.5    Ray, A.6
  • 22
    • 19944416542 scopus 로고    scopus 로고
    • CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation
    • Westendorf A.M., Templin M., Geffers R., et al. CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation. Gut 54 (2005) 60-69
    • (2005) Gut , vol.54 , pp. 60-69
    • Westendorf, A.M.1    Templin, M.2    Geffers, R.3
  • 23
    • 2542477129 scopus 로고    scopus 로고
    • Starting at the beginning: new perspectives on the biology of mucosal T cells
    • Cheroutre H. Starting at the beginning: new perspectives on the biology of mucosal T cells. Annu Rev Immunol 22 (2004) 217-246
    • (2004) Annu Rev Immunol , vol.22 , pp. 217-246
    • Cheroutre, H.1
  • 24
    • 0035717011 scopus 로고    scopus 로고
    • The proportion of Th1 cells, which prevail in gut mucosa, is decreased in inflammatory bowel syndrome
    • Van Damme N., De Keyser F., Demetter P., et al. The proportion of Th1 cells, which prevail in gut mucosa, is decreased in inflammatory bowel syndrome. Clin Exp Immunol 125 (2001) 383-390
    • (2001) Clin Exp Immunol , vol.125 , pp. 383-390
    • Van Damme, N.1    De Keyser, F.2    Demetter, P.3
  • 25
    • 0037354852 scopus 로고    scopus 로고
    • Alteration of intestinal intraepithelial lymphocytes after massive small bowel resection
    • Yang H., Fan Y., Finaly R., and Teitelbaum D.H. Alteration of intestinal intraepithelial lymphocytes after massive small bowel resection. J Surg Res 110 (2003) 276-286
    • (2003) J Surg Res , vol.110 , pp. 276-286
    • Yang, H.1    Fan, Y.2    Finaly, R.3    Teitelbaum, D.H.4
  • 26
    • 0037013968 scopus 로고    scopus 로고
    • A unique subset of self-specific intraintestinal T cells maintains gut integrity
    • Poussier P., Ning T., Banerjee D., and Julius M. A unique subset of self-specific intraintestinal T cells maintains gut integrity. J Exp Med 195 (2002) 1491-1497
    • (2002) J Exp Med , vol.195 , pp. 1491-1497
    • Poussier, P.1    Ning, T.2    Banerjee, D.3    Julius, M.4
  • 28
    • 0032513971 scopus 로고    scopus 로고
    • Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria
    • Kurtzhals J.A., Adabayeri V., Goka B.Q., Akanmori B.D., Oliver-Commey J.O., Nkrumah F.K., et al. Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. Lancet 351 (1998) 1768-1772
    • (1998) Lancet , vol.351 , pp. 1768-1772
    • Kurtzhals, J.A.1    Adabayeri, V.2    Goka, B.Q.3    Akanmori, B.D.4    Oliver-Commey, J.O.5    Nkrumah, F.K.6
  • 29
    • 0032955893 scopus 로고    scopus 로고
    • IL-10 in HIV infection: increasing serum IL-10 levels with disease progression - down-regulatory effect of potent anti-retroviral therapy
    • Stylianou E., Aukrust P., Kvale D., Muller F., and Froland S.S. IL-10 in HIV infection: increasing serum IL-10 levels with disease progression - down-regulatory effect of potent anti-retroviral therapy. Clin Exp Immunol 116 (1999) 115-120
    • (1999) Clin Exp Immunol , vol.116 , pp. 115-120
    • Stylianou, E.1    Aukrust, P.2    Kvale, D.3    Muller, F.4    Froland, S.S.5
  • 30
    • 0031939484 scopus 로고    scopus 로고
    • Impact of dietary fat on Th1/Th2 cytokine gene expression in the pancreas and gut of diabetes-prone BB rats
    • Kleemann R., Scott F.W., Worz-Pagenstert U., Nimal Ratnayake W.M., and Kolb H. Impact of dietary fat on Th1/Th2 cytokine gene expression in the pancreas and gut of diabetes-prone BB rats. J Autoimmun 11 (1998) 97-103
    • (1998) J Autoimmun , vol.11 , pp. 97-103
    • Kleemann, R.1    Scott, F.W.2    Worz-Pagenstert, U.3    Nimal Ratnayake, W.M.4    Kolb, H.5
  • 31
    • 0035959265 scopus 로고    scopus 로고
    • Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients
    • Holm T., Berge R.K., Andreassen A.K., et al. Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients. Transplantation 72 (2001) 706-711
    • (2001) Transplantation , vol.72 , pp. 706-711
    • Holm, T.1    Berge, R.K.2    Andreassen, A.K.3
  • 32
    • 0037029649 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
    • Neurath M.F., Weigmann B., Finotto S., et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med 195 (2002) 1129-1143
    • (2002) J Exp Med , vol.195 , pp. 1129-1143
    • Neurath, M.F.1    Weigmann, B.2    Finotto, S.3
  • 33
    • 9744242678 scopus 로고    scopus 로고
    • Omega-3 fatty acids and inflammation
    • Mori T.A., and Beilin L.J. Omega-3 fatty acids and inflammation. Curr Atheroscler Rep 6 (2004) 461-467
    • (2004) Curr Atheroscler Rep , vol.6 , pp. 461-467
    • Mori, T.A.1    Beilin, L.J.2
  • 34
    • 0036931477 scopus 로고    scopus 로고
    • Omega-3 fatty acids in inflammation and autoimmune diseases
    • Simopoulos A.P. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr 21 (2002) 495-505
    • (2002) J Am Coll Nutr , vol.21 , pp. 495-505
    • Simopoulos, A.P.1
  • 35
    • 0036900107 scopus 로고    scopus 로고
    • Dietary fish oil increases tumor necrosis factor secretion but decreases interleukin-10 secretion by murine peritoneal macrophages
    • Petursdottir D.H., Olafsdottir I., and Hardardottir I. Dietary fish oil increases tumor necrosis factor secretion but decreases interleukin-10 secretion by murine peritoneal macrophages. J Nutr 132 (2002) 3740-3743
    • (2002) J Nutr , vol.132 , pp. 3740-3743
    • Petursdottir, D.H.1    Olafsdottir, I.2    Hardardottir, I.3
  • 36
    • 32544451437 scopus 로고    scopus 로고
    • Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers
    • Ferrucci L., Cherubini A., Bandinelli S., et al. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab 91 (2006) 439-446
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 439-446
    • Ferrucci, L.1    Cherubini, A.2    Bandinelli, S.3
  • 37
    • 0034035020 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 gene transfer ameliorates acute lung allograft rejection
    • Mora B.N., Boasquevisque C.H., Boglione M., et al. Transforming growth factor-beta1 gene transfer ameliorates acute lung allograft rejection. J Thorac Cardiovasc Surg 119 (2000) 913-920
    • (2000) J Thorac Cardiovasc Surg , vol.119 , pp. 913-920
    • Mora, B.N.1    Boasquevisque, C.H.2    Boglione, M.3
  • 38
    • 0028181297 scopus 로고
    • Increased TGF-beta and decreased oncogene expression by omega-3 fatty acids in the spleen delays onset of autoimmune disease in B/W mice
    • Fernandes G., Bysani C., Venkatraman J.T., Tomar V., and Zhao W. Increased TGF-beta and decreased oncogene expression by omega-3 fatty acids in the spleen delays onset of autoimmune disease in B/W mice. J Immunol 152 (1994) 5979-5987
    • (1994) J Immunol , vol.152 , pp. 5979-5987
    • Fernandes, G.1    Bysani, C.2    Venkatraman, J.T.3    Tomar, V.4    Zhao, W.5
  • 39
    • 1342302808 scopus 로고    scopus 로고
    • Teaching tired T cells to fight HIV: time to test IL-15 for immunotherapy?
    • Mastroianni C.M., d'Ettorre G., Forcina G., and Vullo V. Teaching tired T cells to fight HIV: time to test IL-15 for immunotherapy?. Trends Immunol 25 (2004) 121-125
    • (2004) Trends Immunol , vol.25 , pp. 121-125
    • Mastroianni, C.M.1    d'Ettorre, G.2    Forcina, G.3    Vullo, V.4
  • 40
    • 0027437465 scopus 로고
    • Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts
    • Murphy W.J., Back T.C., Conlon K.C., Komschlies K.L., Ortaldo J.R., Sayers T.J., et al. Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts. J Clin Invest 92 (1993) 1918-1924
    • (1993) J Clin Invest , vol.92 , pp. 1918-1924
    • Murphy, W.J.1    Back, T.C.2    Conlon, K.C.3    Komschlies, K.L.4    Ortaldo, J.R.5    Sayers, T.J.6
  • 41
    • 0031570451 scopus 로고    scopus 로고
    • IL-15 enhances immune functions during HIV infection
    • Chehimi J., Marshall J.D., Salvucci O., et al. IL-15 enhances immune functions during HIV infection. J Immunol 158 (1997) 5978-5987
    • (1997) J Immunol , vol.158 , pp. 5978-5987
    • Chehimi, J.1    Marshall, J.D.2    Salvucci, O.3
  • 42
    • 0030845530 scopus 로고    scopus 로고
    • Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome
    • Agostini C., Trentin L., Sancetta R., et al. Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome. Blood 90 (1997) 1115-1123
    • (1997) Blood , vol.90 , pp. 1115-1123
    • Agostini, C.1    Trentin, L.2    Sancetta, R.3
  • 43
    • 0042324649 scopus 로고    scopus 로고
    • Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease
    • Mention J.J., Ben Ahmed M., Begue B., et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 125 (2003) 730-745
    • (2003) Gastroenterology , vol.125 , pp. 730-745
    • Mention, J.J.1    Ben Ahmed, M.2    Begue, B.3
  • 44
    • 33646466776 scopus 로고    scopus 로고
    • MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 alpha alpha TCR alpha beta and TCR gamma delta intestinal intraepithelial lymphocytes
    • Yu Q., Tang C., Xun S., Yajima T., Takeda K., and Yoshikai Y. MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 alpha alpha TCR alpha beta and TCR gamma delta intestinal intraepithelial lymphocytes. J Immunol 176 (2006) 6180-6185
    • (2006) J Immunol , vol.176 , pp. 6180-6185
    • Yu, Q.1    Tang, C.2    Xun, S.3    Yajima, T.4    Takeda, K.5    Yoshikai, Y.6
  • 45
    • 0035884422 scopus 로고    scopus 로고
    • Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells
    • Lewis E., Weiler M., Chaimovitz C., and Douvdevani A. Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells. Transplantation 72 (2001) 886-890
    • (2001) Transplantation , vol.72 , pp. 886-890
    • Lewis, E.1    Weiler, M.2    Chaimovitz, C.3    Douvdevani, A.4
  • 46
    • 0032699153 scopus 로고    scopus 로고
    • The macrophage-derived T-cell growth factor interleukin-15 is present in interleukin-2-independent rejection after clinical heart and liver transplantation
    • Baan C.C., Knoop C.J., Holweg C.T., et al. The macrophage-derived T-cell growth factor interleukin-15 is present in interleukin-2-independent rejection after clinical heart and liver transplantation. Transplant Proc 31 (1999) 2726-2728
    • (1999) Transplant Proc , vol.31 , pp. 2726-2728
    • Baan, C.C.1    Knoop, C.J.2    Holweg, C.T.3
  • 47
    • 0006472715 scopus 로고    scopus 로고
    • Differential expression of T-cell growth factors in rejecting murine islet and human renal allografts: conspicuous absence of interleukin (IL)-9 despite expression of IL-2, IL-4, IL-7, and IL-15
    • Li X.C., Schachter A.D., Zand M.S., Li Y., Zheng X.X., Harmon W.E., et al. Differential expression of T-cell growth factors in rejecting murine islet and human renal allografts: conspicuous absence of interleukin (IL)-9 despite expression of IL-2, IL-4, IL-7, and IL-15. Transplantation 66 (1998) 265-268
    • (1998) Transplantation , vol.66 , pp. 265-268
    • Li, X.C.1    Schachter, A.D.2    Zand, M.S.3    Li, Y.4    Zheng, X.X.5    Harmon, W.E.6


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