Comparison of extracellular striatal acetylcholine and brain seizure activity following acute exposure to the nerve agents cyclosarin and tabun in freely moving guinea pigs

Toxicology Mechanisms and Methods

Volumn 20, Issue 9, 2010, Pages 600-608

  O'Donnell, John C ^a   Acon Chen, Cindy ^a   McDonough, John H ^a   Shih, Tsung Ming ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Acetylcholine; Acetylcholinesterase; Cholinesterase inhibitors; Cyclosarin; In vivo microdialysis; Lethality; Nerve agents; Organophosphorus compounds; Seizure activity; Tabun.

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE; CYCLOSARIN; TABUN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICHOLINERGIC EFFECT; ARTICLE; BEHAVIOR; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; CORPUS STRIATUM; ELECTROENCEPHALOGRAPHY; ENZYME ACTIVITY; ERYTHROCYTE; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LD 50; LEUKOCYTE; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; BRAIN; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASES; CORPUS STRIATUM; GUINEA PIGS; MALE; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHORIC ACID ESTERS; SEIZURES;

CAVIA;

EID: 77958558355     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2010.521208     Document Type: Article

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