Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs

Toxicology Mechanisms and Methods

Volumn 20, Issue 3, 2010, Pages 143-152

  O'Donnell, John C ^a   McDonough, John H ^a   Shih, Tsung Ming ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Acetylcholine; Acetylcholinesterase; Choline; Guinea pig; In vivo microdialysis; Nerve agents; Organophosphorus compounds; Sarin; Seizure activity; Soman; VR; VX

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; SARIN; SOMAN;

ACUTE DISEASE; ANIMAL EXPERIMENT; ARTICLE; BLOOD; CELL LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; ELECTROCORTICOGRAPHY; ELECTROENCEPHALOGRAM; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ERYTHROCYTE; EXTRACELLULAR SPACE; GUINEA PIG; IN VIVO STUDY; LD 50; LETHALITY; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SURVIVAL RATE;

ACETYLCHOLINE; ANIMALS; BRAIN; CHEMICAL WARFARE AGENTS; CHOLINE; CHOLINESTERASE INHIBITORS; CORPUS STRIATUM; ELECTROENCEPHALOGRAPHY; GUINEA PIGS; MALE; ORGANOTHIOPHOSPHORUS COMPOUNDS; SARIN; SEIZURES; SOMAN;

ANIMALIA; CAVIA;

EID: 77149179336     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376511003657439     Document Type: Article

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