Synthesis and biological evaluation of [D-lysine]8cyclosporin A analogs as potential anti-HCV agents

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6542-6546

  Scribner, Andrew ^a   Houck, David ^a   Huang, Zhuhui ^b   Mosier, Sarah ^a   Peel, Michael ^a   Scorneaux, Bernard ^a  

^a SCYNEXIS Inc   (United States)

^b SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Cyclophilin; Cyclosporin; Hepatitis C

Indexed keywords

ANTIVIRUS AGENT; CYCLOSPORIN A DERIVATIVE; CYCLOSPORIN A [3 N METHYL DEXTRO ALANINE 4 N ETHYLVALINE]; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; SCY 635; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS;

HEPATITIS C VIRUS;

EID: 77958049066     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.036     Document Type: Article

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