Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 1, 2000, Pages 143-149

  Cruz, M Cristina ^a   Del Poeta, Maurizio ^a,c   Wang, Ping ^a   Wenger, Roland ^d   Zenke, Gerhard ^d   Quesniaux, Valerie F J ^d   Movva, N Rao ^d   Perfect, John R ^a   Cardenas, Maria E ^a   Heitman, Joseph ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CALCINEURIN; CYCLOPHILIN A; CYCLOSPORIN DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; PHOSPHOPROTEIN PHOSPHATASE;

ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; FUNGUS GROWTH; LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE;

EID: 0033986998     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.1.143-149.2000     Document Type: Article

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