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Volumn 8, Issue 21, 2010, Pages 4905-4914
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Combination of chiroptical, absorption and fluorescence spectroscopic methods reveals multiple, hydrophobicity-driven human serum albumin binding of the antimalarial atovaquone and related hydroxynaphthoquinone compounds
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Author keywords
[No Author keywords available]
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Indexed keywords
ANIONIC SPECIES;
AQUEOUS SOLUTIONS;
ATOVAQUONE;
BINDING AFFINITIES;
CD SPECTRA;
CIRCULAR DICHROISM;
HIGH-AFFINITY BINDING SITES;
HUMAN SERUM ALBUMINS;
HYDROPHOBIC INTERACTIONS;
HYDROXYL GROUPS;
LAWSONE;
NAPHTHOQUINONE;
PHYSIOLOGICAL PH;
PLASMA PROTEIN;
RADIOACTIVE MARKERS;
SPECTROSCOPIC METHOD;
UV/VIS SPECTRA;
ABSORPTION;
ACIDS;
AFFINITY CHROMATOGRAPHY;
BINDING ENERGY;
BIOCHEMISTRY;
BODY FLUIDS;
CIRCULAR DICHROISM SPECTROSCOPY;
COMPLEXATION;
DICHROISM;
DRUG INTERACTIONS;
DRUG PRODUCTS;
DYES;
FLUORESCENCE;
FLUORESCENCE SPECTROSCOPY;
HYDROPHOBIC CHROMATOGRAPHY;
HYDROPHOBICITY;
KETONES;
PH EFFECTS;
SOLUTIONS;
SPECTROSCOPIC ANALYSIS;
BINDING SITES;
ANTIMALARIAL AGENT;
ATOVAQUONE;
DRUG DERIVATIVE;
SERUM ALBUMIN;
AFFINITY CHROMATOGRAPHY;
ARTICLE;
CHEMICAL STRUCTURE;
CHEMISTRY;
CIRCULAR DICHROISM;
HUMAN;
METABOLISM;
PROTEIN BINDING;
SPECTROFLUOROMETRY;
SPECTROPHOTOMETRY;
ANTIMALARIALS;
ATOVAQUONE;
CHROMATOGRAPHY, AFFINITY;
CIRCULAR DICHROISM;
HUMANS;
MODELS, MOLECULAR;
PROTEIN BINDING;
SERUM ALBUMIN;
SPECTROMETRY, FLUORESCENCE;
SPECTROPHOTOMETRY;
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EID: 77957923612
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/c0ob00124d Document Type: Article |
Times cited : (15)
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References (44)
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