Conformation selectivity in the binding of diazepam and analogues to α1-acid glycoprotein

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 14, 2007, Pages 4857-4862

  Fitos, Ilona ^a   Visy, Júlia ^a   Zsila, Ferenc ^a   Mády, György ^a   Simonyi, Miklós ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

1 Acid glycoprotein; Benzodiazepine conformation; Diazepam; Genetic variants; Induced circular dichroism; Protein binding

Indexed keywords

3 METHYLNORDAZEPAM; 3,3 DIMETHYLDIAZEPAM; 3,3 DIMETHYLNORDAZEPAM; DIAZEPAM; DIAZEPAM DERIVATIVE; LORAZEPAM ACETATE; NORDAZEPAM; OROSOMUCOID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; DRUG PROTEIN BINDING; DRUG SELECTIVITY; ENANTIOMER; PROTEIN CONFORMATION;

CIRCULAR DICHROISM; DIAZEPAM; HUMANS; MOLECULAR CONFORMATION; OROSOMUCOID; PROTEIN BINDING; SERUM ALBUMIN; VARIATION (GENETICS);

EID: 34249667648     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.04.060     Document Type: Article

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