메뉴 건너뛰기




Volumn 5, Issue 8, 2010, Pages

Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56γ and genotoxic stress

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ALANINE; ATM PROTEIN; CASEIN KINASE I; CASEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; MESSENGER RNA; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2A B56GAMMA; PROTEIN SUBUNIT; SERINE; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 1; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 77957858886     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012173     Document Type: Article
Times cited : (22)

References (38)
  • 1
    • 0035430282 scopus 로고    scopus 로고
    • Transcriptional regulation by the phosphorylation-dependent factor CREB
    • Mayr B, Montminy M (2001) Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2: 599-609.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 599-609
    • Mayr, B.1    Montminy, M.2
  • 2
    • 20144379523 scopus 로고    scopus 로고
    • Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
    • Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, et al. (2005) Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci USA 102: 4459-4464.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4459-4464
    • Zhang, X.1    Odom, D.T.2    Koo, S.H.3    Conkright, M.D.4    Canettieri, G.5
  • 3
    • 19944367254 scopus 로고    scopus 로고
    • Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions
    • Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS, et al. (2004) Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell 119: 1041-1054.
    • (2004) Cell , vol.119 , pp. 1041-1054
    • Impey, S.1    McCorkle, S.R.2    Cha-Molstad, H.3    Dwyer, J.M.4    Yochum, G.S.5
  • 4
    • 2342595896 scopus 로고    scopus 로고
    • The CREB family: Key regulators of hepatic metabolism
    • Montminy M, Koo SH, Zhang X (2004) The CREB family: key regulators of hepatic metabolism. Ann Endocrinol (Paris) 65: 73-75.
    • (2004) Ann Endocrinol (Paris) , vol.65 , pp. 73-75
    • Montminy, M.1    Koo, S.H.2    Zhang, X.3
  • 5
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • Lonze BE, Ginty DD (2002) Function and regulation of CREB family transcription factors in the nervous system. Neuron 35: 605-623.
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 6
    • 60649091912 scopus 로고    scopus 로고
    • Adipocyte CREB promotes insulin resistance in obesity
    • Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, et al. (2009) Adipocyte CREB promotes insulin resistance in obesity. Cell Metab 9: 277-286.
    • (2009) Cell Metab , vol.9 , pp. 277-286
    • Qi, L.1    Saberi, M.2    Zmuda, E.3    Wang, Y.4    Altarejos, J.5
  • 7
    • 17444403591 scopus 로고    scopus 로고
    • The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia
    • Shankar DB, Cheng JC, Kinjo K, Federman N, Moore TB, et al. (2005) The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Cancer Cell 7: 351-362.
    • (2005) Cancer Cell , vol.7 , pp. 351-362
    • Shankar, D.B.1    Cheng, J.C.2    Kinjo, K.3    Federman, N.4    Moore, T.B.5
  • 8
    • 24344482544 scopus 로고    scopus 로고
    • CREB: The unindicted cancer coconspirator
    • Conkright MD, Montminy M (2005) CREB: the unindicted cancer coconspirator. Trends Cell Biol 15: 457-459.
    • (2005) Trends Cell Biol , vol.15 , pp. 457-459
    • Conkright, M.D.1    Montminy, M.2
  • 9
    • 0027433708 scopus 로고
    • Phosphorylated CREB binds specifically to the nuclear protein CBP
    • Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, et al. (1993) Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859.
    • (1993) Nature , vol.365 , pp. 855-859
    • Chrivia, J.C.1    Kwok, R.P.2    Lamb, N.3    Hagiwara, M.4    Montminy, M.R.5
  • 10
    • 0030058682 scopus 로고    scopus 로고
    • Phosphorylation of CREB at Ser-133 induces complex formation with CREBbinding protein via a direct mechanism
    • Parker D, Ferreri K, Nakajima T, LaMorte VJ, Evans R, et al. (1996) Phosphorylation of CREB at Ser-133 induces complex formation with CREBbinding protein via a direct mechanism. Mol Cell Biol 16: 694-703.
    • (1996) Mol Cell Biol , vol.16 , pp. 694-703
    • Parker, D.1    Ferreri, K.2    Nakajima, T.3    Lamorte, V.J.4    Evans, R.5
  • 12
    • 0142091390 scopus 로고    scopus 로고
    • Identification of a family of cAMP response element-binding protein coactivators by genomescale functional analysis in mammalian cells
    • Iourgenko V, Zhang W, Mickanin C, Daly I, Jiang C, et al. (2003) Identification of a family of cAMP response element-binding protein coactivators by genomescale functional analysis in mammalian cells. Proc Natl Acad Sci U S A 100: 12147-12152.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12147-12152
    • Iourgenko, V.1    Zhang, W.2    Mickanin, C.3    Daly, I.4    Jiang, C.5
  • 13
    • 34250814515 scopus 로고    scopus 로고
    • Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression
    • Ravnskjaer K, Kester H, Liu Y, Zhang X, Lee D, et al. (2007) Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. Embo J 26: 2880-2889.
    • (2007) Embo J , vol.26 , pp. 2880-2889
    • Ravnskjaer, K.1    Kester, H.2    Liu, Y.3    Zhang, X.4    Lee, D.5
  • 14
    • 27144506185 scopus 로고    scopus 로고
    • The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
    • Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, et al. (2005) The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437: 1109-1111.
    • (2005) Nature , vol.437 , pp. 1109-1111
    • Koo, S.H.1    Flechner, L.2    Qi, L.3    Zhang, X.4    Screaton, R.A.5
  • 15
    • 0032852479 scopus 로고    scopus 로고
    • CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • Shaywitz AJ, Greenberg ME (1999) CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68: 821-861.
    • (1999) Annu Rev Biochem , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 16
    • 33846002009 scopus 로고    scopus 로고
    • Functional characterization of male germ cell-specific CREM isoforms
    • Jaspers S, Gellersen B, Kempf R, Samalecos A, Bergmann M, et al. (2007) Functional characterization of male germ cell-specific CREM isoforms. J Androl 28: 59-66.
    • (2007) J Androl , vol.28 , pp. 59-66
    • Jaspers, S.1    Gellersen, B.2    Kempf, R.3    Samalecos, A.4    Bergmann, M.5
  • 17
    • 0036176872 scopus 로고    scopus 로고
    • Activating transcription factor 1 and CREB are important for cell survival during early mouse development
    • Bleckmann SC, Blendy JA, Rudolph D, Monaghan AP, Schmid W, et al. (2002) Activating transcription factor 1 and CREB are important for cell survival during early mouse development. Mol Cell Biol 22: 1919-1925.
    • (2002) Mol Cell Biol , vol.22 , pp. 1919-1925
    • Bleckmann, S.C.1    Blendy, J.A.2    Rudolph, D.3    Monaghan, A.P.4    Schmid, W.5
  • 18
    • 33644991073 scopus 로고    scopus 로고
    • DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM
    • Dodson GE, Tibbetts RS (2006) DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM. J Biol Chem 281: 1692-1697.
    • (2006) J Biol Chem , vol.281 , pp. 1692-1697
    • Dodson, G.E.1    Tibbetts, R.S.2
  • 19
    • 34250375258 scopus 로고    scopus 로고
    • Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage
    • Shanware NP, Trinh AT, Williams LM, Tibbetts RS (2007) Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage. J Biol Chem 282: 6283-6291.
    • (2007) J Biol Chem , vol.282 , pp. 6283-6291
    • Shanware, N.P.1    Trinh, A.T.2    Williams, L.M.3    Tibbetts, R.S.4
  • 20
    • 1942437537 scopus 로고    scopus 로고
    • Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress
    • Shi Y, Venkataraman SL, Dodson GE, Mabb AM, LeBlanc S, et al. (2004) Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. Proc Natl Acad Sci USA 101: 5898-5903.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 5898-5903
    • Shi, Y.1    Venkataraman, S.L.2    Dodson, G.E.3    Mabb, A.M.4    Leblanc, S.5
  • 21
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim ST, Lim DS, Canman CE, Kastan MB (1999) Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem 274: 37538-37543.
    • (1999) J Biol Chem , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 22
    • 13844294211 scopus 로고    scopus 로고
    • The casein kinase 1 family: Participation in multiple cellular processes in eukaryotes
    • Knippschild U, Gocht A, Wolff S, Huber N, Lohler J, et al. (2005) The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cell Signal 17: 675-689.
    • (2005) Cell Signal , vol.17 , pp. 675-689
    • Knippschild, U.1    Gocht, A.2    Wolff, S.3    Huber, N.4    Lohler, J.5
  • 23
    • 0037334895 scopus 로고    scopus 로고
    • One-thousand-and-one substrates of protein kinase CK2?
    • Meggio F, Pinna LA (2003) One-thousand-and-one substrates of protein kinase CK2? Faseb J 17: 349-368.
    • (2003) Faseb J , vol.17 , pp. 349-368
    • Meggio, F.1    Pinna, L.A.2
  • 24
    • 1242276189 scopus 로고    scopus 로고
    • D4476, a cell-permeant inhibitor ofCK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
    • Rena G, Bain J, Elliott M, Cohen P (2004) D4476, a cell-permeant inhibitor ofCK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO Rep 5: 60-65.
    • (2004) EMBO Rep , vol.5 , pp. 60-65
    • Rena, G.1    Bain, J.2    Elliott, M.3    Cohen, P.4
  • 25
    • 0037093352 scopus 로고    scopus 로고
    • Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells
    • Ruzzene M, Penzo D, Pinna LA (2002) Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. Biochem J 364: 41-47.
    • (2002) Biochem J , vol.364 , pp. 41-47
    • Ruzzene, M.1    Penzo, D.2    Pinna, L.A.3
  • 26
    • 9744271049 scopus 로고    scopus 로고
    • Identification and characterization of a novel and specific inhibitor of the ataxiatelangiectasia mutated kinase ATM
    • Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, et al. (2004) Identification and characterization of a novel and specific inhibitor of the ataxiatelangiectasia mutated kinase ATM. Cancer Res 64: 9152-9159.
    • (2004) Cancer Res , vol.64 , pp. 9152-9159
    • Hickson, I.1    Zhao, Y.2    Richardson, C.J.3    Green, S.J.4    Martin, N.M.5
  • 27
    • 34447275978 scopus 로고    scopus 로고
    • Small-molecule inhibitors of ser/thr protein phosphatases: Specificity, use and common forms of abuse
    • Swingle M, Ni L, Honkanen RE (2007) Small-molecule inhibitors of ser/thr protein phosphatases: specificity, use and common forms of abuse. Methods Mol Biol 365: 23-38.
    • (2007) Methods Mol Biol , vol.365 , pp. 23-38
    • Swingle, M.1    Ni, L.2    Honkanen, R.E.3
  • 28
    • 0023691731 scopus 로고
    • Inhibitory effect of a marine-sponge toxin, okadaicacid, on protein phosphatases. Specificity and kinetics
    • Bialojan C, Takai A (1988) Inhibitory effect of a marine-sponge toxin, okadaicacid, on protein phosphatases. Specificity and kinetics. Biochem J 256: 283-290.
    • (1988) Biochem J , vol.256 , pp. 283-290
    • Bialojan, C.1    Takai, A.2
  • 30
    • 33846542682 scopus 로고    scopus 로고
    • A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55
    • Li HH, Cai X, Shouse GP, Piluso LG, Liu X (2007) A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55. Embo J 26: 402-411.
    • (2007) Embo J , vol.26 , pp. 402-411
    • Li, H.H.1    Cai, X.2    Shouse, G.P.3    Piluso, L.G.4    Liu, X.5
  • 31
    • 37549003306 scopus 로고    scopus 로고
    • Serine 15 phosphorylation of p53 directs its interaction with B56gamma and the tumor suppressor activity of B56gammaspecific protein phosphatase 2A
    • Shouse GP, Cai X, Liu X (2008) Serine 15 phosphorylation of p53 directs its interaction with B56gamma and the tumor suppressor activity of B56gammaspecific protein phosphatase 2A. Mol Cell Biol 28: 448-456.
    • (2008) Mol Cell Biol , vol.28 , pp. 448-456
    • Shouse, G.P.1    Cai, X.2    Liu, X.3
  • 32
    • 67449086843 scopus 로고    scopus 로고
    • Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190
    • Shanware NP, Williams LM, Bowler MJ, Tibbetts RS (2009) Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190. BMB Rep 42: 142-147.
    • (2009) BMB Rep , vol.42 , pp. 142-147
    • Shanware, N.P.1    Williams, L.M.2    Bowler, M.J.3    Tibbetts, R.S.4
  • 33
    • 0041332880 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the ATM promoter: Consequences for response to proliferation and ionizing radiation
    • Gueven N, Keating K, Fukao T, Loeffler H, Kondo N, et al. (2003) Site-directed mutagenesis of the ATM promoter: consequences for response to proliferation and ionizing radiation. Genes Chromosomes Cancer 38: 157-167.
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 157-167
    • Gueven, N.1    Keating, K.2    Fukao, T.3    Loeffler, H.4    Kondo, N.5
  • 34
    • 0027257247 scopus 로고
    • In vitro phosphorylation studies of a conserved region of the transcription factor ATF1
    • Masson N, John J, Lee KA (1993) In vitro phosphorylation studies of a conserved region of the transcription factor ATF1. Nucleic Acids Res 21: 4166-4173.
    • (1993) Nucleic Acids Res , vol.21 , pp. 4166-4173
    • Masson, N.1    John, J.2    Lee, K.A.3
  • 35
    • 0025944454 scopus 로고
    • Differential regulation of three members of the ATF/CREB family of DNA-binding proteins
    • Flint KJ, Jones NC (1991) Differential regulation of three members of the ATF/CREB family of DNA-binding proteins. Oncogene 6: 2019-2026.
    • (1991) Oncogene , vol.6 , pp. 2019-2026
    • Flint, K.J.1    Jones, N.C.2
  • 36
    • 34547927079 scopus 로고    scopus 로고
    • PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive elemen
    • Iwasaki K, Hailemariam K, Tsuji Y (2007) PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive elemen. J Biol Chem 282: 22335-22343.
    • (2007) J Biol Chem , vol.282 , pp. 22335-22343
    • Iwasaki, K.1    Hailemariam, K.2    Tsuji, Y.3
  • 37
    • 34447502427 scopus 로고    scopus 로고
    • Activating transcription factor-1-mediated hepatocyte growth factorinduced down-regulation of thrombospondin-1 expression leads to thyroid cancer cell invasion
    • Ghoneim C, Soula-Rothhut M, Blanchevoye C, Martiny L, Antonicelli F, et al. (2007) Activating transcription factor-1-mediated hepatocyte growth factorinduced down-regulation of thrombospondin-1 expression leads to thyroid cancer cell invasion. J Biol Chem 282: 15490-15497.
    • (2007) J Biol Chem , vol.282 , pp. 15490-15497
    • Ghoneim, C.1    Soula-Rothhut, M.2    Blanchevoye, C.3    Martiny, L.4    Antonicelli, F.5
  • 38
    • 0034460485 scopus 로고    scopus 로고
    • Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein
    • Shaywitz AJ, Dove SL, Kornhauser JM, Hochschild A, Greenberg ME (2000) Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein. Mol Cell Biol 20: 9409-9422.
    • (2000) Mol Cell Biol , vol.20 , pp. 9409-9422
    • Shaywitz, A.J.1    Dove, S.L.2    Kornhauser, J.M.3    Hochschild, A.4    Greenberg, M.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.