-
1
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Hakkenist, C. J., and M. B. Kastan. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Hakkenist, C.J.1
Kastan, M.B.2
-
2
-
-
4944255743
-
Post-translational modifications of p53 in tumorigenesis
-
Bode, A. M., and Z. Dong. 2004. Post-translational modifications of p53 in tumorigenesis. Nat. Rev. 4:793-805.
-
(2004)
Nat. Rev
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
3
-
-
1442310493
-
Identification of specific PP2A complexes involved in human cell transformation
-
Chen, W., R. Possemato, K. T. Campbell, C. A. Plattner, D. C. Pallas, and W. C. Hahn. 2004. Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell 5:127-136.
-
(2004)
Cancer Cell
, vol.5
, pp. 127-136
-
-
Chen, W.1
Possemato, R.2
Campbell, K.T.3
Plattner, C.A.4
Pallas, D.C.5
Hahn, W.C.6
-
4
-
-
0033567340
-
Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 protein are modified in human cancers
-
Craig, A. L., L. Burch, B. Vojtesek, J. Mikuowska, A. Thompson, and T. R. Hupp. 1999. Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 protein are modified in human cancers. Biochem. J. 342:133-141.
-
(1999)
Biochem. J
, vol.342
, pp. 133-141
-
-
Craig, A.L.1
Burch, L.2
Vojtesek, B.3
Mikuowska, J.4
Thompson, A.5
Hupp, T.R.6
-
5
-
-
0030047451
-
High complexity in the expression of the B′ subunit of protein phosphatase 2A: Evidence for the existence of at least seven novel isoforms
-
Csortos, C., S. Zolnierowicz, E. Bako, S. D. Durbin, and A. A. DePaoli-Roach. 1996. High complexity in the expression of the B′ subunit of protein phosphatase 2A: evidence for the existence of at least seven novel isoforms. J. Biol. Chem. 271:2578-2588.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 2578-2588
-
-
Csortos, C.1
Zolnierowicz, S.2
Bako, E.3
Durbin, S.D.4
DePaoli-Roach, A.A.5
-
6
-
-
0038508864
-
DNA-dependent acetylation of p53 by the transcription coactivator p300
-
Dornan, D., H. Shimizu, N. D. Perkins, and T. R. Hupp. 2003. DNA-dependent acetylation of p53 by the transcription coactivator p300. J. Biol. Chem. 278:13431-13441.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 13431-13441
-
-
Dornan, D.1
Shimizu, H.2
Perkins, N.D.3
Hupp, T.R.4
-
7
-
-
0034664044
-
Phosphorylation of human p53 on Thr55
-
Gatti, A., H.-H. Li, J. A. Traugh, and X. Liu. 2000. Phosphorylation of human p53 on Thr55. Biochemistry 39:9837-9842.
-
(2000)
Biochemistry
, vol.39
, pp. 9837-9842
-
-
Gatti, A.1
Li, H.-H.2
Traugh, J.A.3
Liu, X.4
-
8
-
-
9744271049
-
Identification and characterization of a novel specific inhibitor of the Ataxia-Telangiectasia Mutated kinase ATM
-
Hickson, I., Y. Zhao, C. J. Richardson, S. J. Green, N. M. B. Martin, A. I. Orr, P. M. Reaper, S. P. Jackson, N. J. Curtin, and G. M. C. Smith. 2004. Identification and characterization of a novel specific inhibitor of the Ataxia-Telangiectasia Mutated kinase ATM. Cancer Res. 64:9152-9159.
-
(2004)
Cancer Res
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.B.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.M.C.10
-
10
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert, P. F., F. Kashanchi, M. F. Radonovich, R. Shiekhattar, and J. N. Brady. 1998. Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273:33048-33053.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
11
-
-
10444237214
-
ATM signaling and genomic stability in response to DNA damage
-
Lavin, M. F., G. Birrell, P. Chen, S. Kozlov, S. Scott, and N. Gueven. 2005. ATM signaling and genomic stability in response to DNA damage. Mutat. Res. 569:123-132.
-
(2005)
Mutat. Res
, vol.569
, pp. 123-132
-
-
Lavin, M.F.1
Birrell, G.2
Chen, P.3
Kozlov, S.4
Scott, S.5
Gueven, N.6
-
13
-
-
33846542682
-
A specific PP2A regulatory subunit, B56γ, mediates DNA damage-induced dephosphorylation of p53 at Thr55
-
Li, H.-H., X. Cai, G. P. Shouse, L. G. Piluso, and X. Liu. 2007. A specific PP2A regulatory subunit, B56γ, mediates DNA damage-induced dephosphorylation of p53 at Thr55. EMBO J. 26:402-411.
-
(2007)
EMBO J
, vol.26
, pp. 402-411
-
-
Li, H.-H.1
Cai, X.2
Shouse, G.P.3
Piluso, L.G.4
Liu, X.5
-
14
-
-
0034611728
-
ATM phosphorylates p95/nbs1 in a S-phase checkpoint pathway
-
Lim, D.-S., S.-T. Kim, B. Xu, R. S. Maser, J. Lin, J. H. J. Petrini, and M. B. Kastan. 2000. ATM phosphorylates p95/nbs1 in a S-phase checkpoint pathway. Nature 404:613-617.
-
(2000)
Nature
, vol.404
, pp. 613-617
-
-
Lim, D.-S.1
Kim, S.-T.2
Xu, B.3
Maser, R.S.4
Lin, J.5
Petrini, J.H.J.6
Kastan, M.B.7
-
15
-
-
33751212191
-
Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
-
Margolis, S. S., J. A. Perry, C. M. Forester, L. K. Nutt, Y. Guo, M. J. Jardim, M. J. Thomenius, C. D. Freel, R. Darbandi, J.-H. Ahn, J. D. Arroyo, X.-F. Wang, S. Shenolikar, A. C. Nairn, W. G. Dunphy, W. C. Hahn, D. M. Virshup, and S. Kornbluth. 2006. Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell 127:759-773.
-
(2006)
Cell
, vol.127
, pp. 759-773
-
-
Margolis, S.S.1
Perry, J.A.2
Forester, C.M.3
Nutt, L.K.4
Guo, Y.5
Jardim, M.J.6
Thomenius, M.J.7
Freel, C.D.8
Darbandi, R.9
Ahn, J.-H.10
Arroyo, J.D.11
Wang, X.-F.12
Shenolikar, S.13
Nairn, A.C.14
Dunphy, W.G.15
Hahn, W.C.16
Virshup, D.M.17
Kornbluth, S.18
-
16
-
-
0030586955
-
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm
-
McCright, B., A. R. Brothman, and D. M. Virshup. 1996. The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. Genomics 36:168-170.
-
(1996)
Genomics
, vol.36
, pp. 168-170
-
-
McCright, B.1
Brothman, A.R.2
Virshup, D.M.3
-
17
-
-
0036199651
-
Genomic organization and mapping of the gene encoding the PP2A B56gamma regulatory subunit
-
Muneer, S., V. Ramalingam, R. Wyatt, R. A. Schultz, J. D. Minna, and C. Kamibayashi. 2002. Genomic organization and mapping of the gene encoding the PP2A B56gamma regulatory subunit. Genomics 79:344-348.
-
(2002)
Genomics
, vol.79
, pp. 344-348
-
-
Muneer, S.1
Ramalingam, V.2
Wyatt, R.3
Schultz, R.A.4
Minna, J.D.5
Kamibayashi, C.6
-
18
-
-
33344476097
-
DNA damage checkpoints in mammals
-
Niida, H., and M. Nakanishi. 2006. DNA damage checkpoints in mammals. Mutagenesis 21:3-9.
-
(2006)
Mutagenesis
, vol.21
, pp. 3-9
-
-
Niida, H.1
Nakanishi, M.2
-
19
-
-
1842527952
-
Expression of the B56delta subunit of protein phosphatase 2A and Mea1 in mouse spermatogenesis. Identification of a new B56gamma subunit (B56gamma4) specifically expressed in testis
-
Ortega-Lazaro, J. C., and J. del Mazo. 2003. Expression of the B56delta subunit of protein phosphatase 2A and Mea1 in mouse spermatogenesis. Identification of a new B56gamma subunit (B56gamma4) specifically expressed in testis. Cytogenet. Genome Res. 103:345-351.
-
(2003)
Cytogenet. Genome Res
, vol.103
, pp. 345-351
-
-
Ortega-Lazaro, J.C.1
del Mazo, J.2
-
20
-
-
0034737438
-
Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by casein 1-like kinase. Effect on Mdm2 binding
-
Sakaguchi, K., S.-I. Saito, Y. Higashimoto, S. Roy, C. W. Anderson, and E. Appella. 2000. Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by casein 1-like kinase. Effect on Mdm2 binding. J. Biol. Chem. 275:9278-9283.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9278-9283
-
-
Sakaguchi, K.1
Saito, S.-I.2
Higashimoto, Y.3
Roy, S.4
Anderson, C.W.5
Appella, E.6
-
21
-
-
0035840446
-
Role of serine/threonine protein phosphatase 2A in cancer
-
Schonthal, A. H. 2001. Role of serine/threonine protein phosphatase 2A in cancer. Cancer Lett. 170:1-13.
-
(2001)
Cancer Lett
, vol.170
, pp. 1-13
-
-
Schonthal, A.H.1
-
22
-
-
0037154221
-
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer
-
Scott, S. P., R. Bendix, P. Chen, R. Clark, T. Dork, and M. F. Lavin. 2002. Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer. Proc. Natl. Acad. Sci. USA 99:925-930.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 925-930
-
-
Scott, S.P.1
Bendix, R.2
Chen, P.3
Clark, R.4
Dork, T.5
Lavin, M.F.6
-
23
-
-
0037067656
-
-
Sharpless, N. E., and R. A. DePinho. 2002. p53: good cop/bad cop. Cell 110:9-12.
-
Sharpless, N. E., and R. A. DePinho. 2002. p53: good cop/bad cop. Cell 110:9-12.
-
-
-
-
24
-
-
33745823159
-
ATM-mediated DNA-damage response: Taking shape
-
Shiloh, Y. 2006. ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31:402-410.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
25
-
-
0035100658
-
Protein phosphatase 2A: The Trojan horse of cellular signaling
-
Sontag, E. 2001. Protein phosphatase 2A: the Trojan horse of cellular signaling. Cell. Signal. 13:7-16.
-
(2001)
Cell. Signal
, vol.13
, pp. 7-16
-
-
Sontag, E.1
-
26
-
-
0038702246
-
Phosphatases in apoptosis: To be or not to be, PP2A is in the heart of the question
-
Van Hoof, C., and J. Goris. 2003. Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question. Biochim. Biophys. Acta 1640:97-104.
-
(2003)
Biochim. Biophys. Acta
, vol.1640
, pp. 97-104
-
-
Van Hoof, C.1
Goris, J.2
-
27
-
-
0034009389
-
Protein phosphatase 2A: A panoply of enzymes
-
Virshup, D. M. 2000. Protein phosphatase 2A: a panoply of enzymes. Curr. Opin. Cell Biol. 12:180-185.
-
(2000)
Curr. Opin. Cell Biol
, vol.12
, pp. 180-185
-
-
Virshup, D.M.1
-
29
-
-
33750006297
-
Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins
-
Xing, Y., Y. Xu, Y. Chen, P. D. Jeffrey, Y. Chao, Z. Lin, Z. Li, S. Strack, J. B. Stock, and Y. Shi. 2006. Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell 127:341-353.
-
(2006)
Cell
, vol.127
, pp. 341-353
-
-
Xing, Y.1
Xu, Y.2
Chen, Y.3
Jeffrey, P.D.4
Chao, Y.5
Lin, Z.6
Li, Z.7
Strack, S.8
Stock, J.B.9
Shi, Y.10
-
30
-
-
33845404441
-
Structure of the protein phosphatase 2A holoenzyme
-
Xu, Y., Y. Xing, Y. Chen, Y. Chao, Z. Lin, E. Fan, J. W. Yu, S. Strack, P. D. Jeffrey, and Y. Shi. 2006. Structure of the protein phosphatase 2A holoenzyme. Cell 127:1239-1251.
-
(2006)
Cell
, vol.127
, pp. 1239-1251
-
-
Xu, Y.1
Xing, Y.2
Chen, Y.3
Chao, Y.4
Lin, Z.5
Fan, E.6
Yu, J.W.7
Strack, S.8
Jeffrey, P.D.9
Shi, Y.10
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