Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190

BMB Reports

Volumn 42, Issue 3, 2009, Pages 142-147

  Shanware, Naval P ^a   Williams, Leah M ^a   Bowler, Michael J ^a   Tibbetts, Randal S ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Casein kinase; CK1; CK2; CREB; Cycloheximide; Non specific; p38; SB202190; SB203580; Stress activated protein kinase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; CASEIN KINASE I; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOSERINE; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE;

ARTICLE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; GENE REPRESSION; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PROTEIN SYNTHESIS;

CASEIN KINASE I; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HUMANS; IMIDAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN BIOSYNTHESIS; PROTEIN KINASE INHIBITORS; PYRIDINES; STRESS, PHYSIOLOGICAL; SUBSTRATE SPECIFICITY; SUPPRESSION, GENETIC;

EID: 67449086843     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2009.42.3.142     Document Type: Article

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